Mindy Kim Graham

Cancer researcher, suspected late bloomer, Siberian forest cat enthusiast, cool mom vibes, @mindykimgraham.bsky.social

[Mindy Kim Graham @MindyKimGraham]

Pleased to see the official release of our research letter in @jclinicalinvest. We leveraged a publicly available scRNA-seq dataset and asked how prostate cancer cells systemically reprogram the cells of the bone marrow.
https://t.co/leAdzw2luu

[Amer. Urol. Assn. @AmerUrological]

👏 Congratulations to our 15 Research Scholar Awardees!

The awardees are rising researchers advancing earlier detection, more personalized therapies and improved outcomes across urologic disease. This year’s awardees represent a diverse range of research areas—from cancer biology and artificial intelligence to pediatric care and infection prevention.

🔗 Click to learn more about the program and the awardees: https://t.co/LYIzitW6Yu

[Mindy Kim Graham @MindyKimGraham]

We found that BM myeloid cells were enriched for IFN-γ signaling and downstream IL-10 receptor, thereby priming myeloid cells for IL-10-mediated immunosuppression in metastatic lesions. This reveals how tumors reprogram the bone marrow to create a permissive premetastatic niche.

[Mindy Kim Graham @MindyKimGraham]

Pleased to see the official release of our research letter in @jclinicalinvest. We leveraged a publicly available scRNA-seq dataset and asked how prostate cancer cells systemically reprogram the cells of the bone marrow.
https://t.co/leAdzw2luu

[Journal of Clinical Investigation @jclinicalinvest]

Prostate tumor–mediated IFNG signaling primes myeloid cells in bone premetastatic niche for immunosuppressive IL-10 signaling

In this Research Letter, Mindy K Graham @MindyKimGraham & team @NorthwesternU report on analysis from a published sc-RNA-Seq dataset involving metastatic tumors of the bone and control tissue.

https://t.co/FiKPxJhhjL

[Mindy Kim Graham @MindyKimGraham]

@jclinicalinvest We found that bone marrow myeloid cells were enriched for IFN-γ signaling, priming them for IL-10-mediated immunosuppression in metastatic lesions. This reveals how tumors reprogram the bone marrow to create a permissive premetastatic niche.

[Mindy Kim Graham @MindyKimGraham]

I’m excited to share my first corresponding author publication in @jclinicalinvest! Leveraging an incredible scRNA-seq dataset from Kfoury et al. (Cancer Cell, 2021), we asked: what changes happen in the bone marrow before overt prostate cancer metastasis? https://t.co/TqV0s6NVzA

[Simona Cristea @simocristea]

from:

https://t.co/ar2LgLlee1

[UroToday.com @urotoday]

MYC’s role in #ProstateCancer immune suppression and progression. @MindyKimGraham @NM_Urology joins @AndreaMiyahira @PCFnews to discuss her research, which reveals how MYC activation drives consistent changes in the tumor microenvironment across both human and mouse models of prostate cancer. #WatchNow > https://t.co/5PYvL8sbnZ @NatureComms

[Rahul Satija @satijalab]

Our Single Cell Genomics Day - highlighting our favorite new sc/spatial methods - starts Friday at 10AM ET!

The most common question we get: is this open to anyone? Yes! Talks are free and live-streamed (no registration required) on Youtube and https://t.co/zG98gkckMU

[Balaji @Bajji]

Big thanks to Johann de Bono and @mishabeltran for the chance to contribute to a timely review on Cell Surface Targets in #ProstateCancer, now out in @NatRevUrol!
It was a fantastic experience learning and collaborating with @cboixareu1 and @TarekTahaMD.

https://t.co/GN3GDjkPf7

[Thor Halfdanarson @OncoThor]

Are you interested in learning more about the management of small panc NETs and how molecular analysis may predict outcomes? If so, I have just the right paper for you... 😀 Thanks to @PancPathologist, Anna Vera Verschuur, C. Heaphy, L. Brosens et al.

https://t.co/taZ7Jzf4Ks

[UroToday.com @urotoday]

MYC’s role in #ProstateCancer immune suppression and progression. @MindyKimGraham @NM_Urology joins @AndreaMiyahira @PCFnews to discuss her research, which reveals how MYC activation drives consistent changes in the tumor microenvironment across both human and mouse models of prostate cancer. #WatchNow > https://t.co/5PYvL8sbnZ @NatureComms

[Caleb Lareau @CalebLareau]

PERFF-seq is out today in @NatureGenet! Our recent thread summarizes why we are excited about the prospects of programmable nucleic acid cytometry for studying rare cell states.

https://t.co/pJZh23AZ1f

[Raimondi Ivan @raimondi_ivan]

🧬 We’re excited to introduce D&D-seq, a single-cell technology that maps DNA:Protein interactions through molecular footprinting.. Check it out here: https://t.co/mfsDO3kKa0 #Genomics #Epigenetics

[Arutha K @aruthak]

🧬 Exciting New #SpatialAnalysis Tool! 🧬
🚀 Introducing PRISM: A powerful Python package for the interactive and integrated analysis of multiplexed tissue microarrays! https://t.co/XfVwDxIYTC

[Luciano Martelotto 🛠🧬💻🇦🇺 @LGMartelotto]

ezSingleCell: an integrated one-stop single-cell and spatial omics analysis platform for bench scientists | Nature Communications https://t.co/zN1lEkRErc

[Clint Miller @clintomics]

Delineating the effective use of self-supervised learning in single-cell genomics ⁦@NatMachIntell⁩ ⁦@fabian_theis⁩ https://t.co/baaEscxdGp

[dana_peer @dana_peer]

This really works wonders on Visium data. In our hands it is by far the best method to deconvolve spots.

[Itai Yanai @ItaiYanai]

My guidelines for exploratory data analysis

[NM Urology @NM_Urology]

Investigators, including first author @MindyKimGraham, PhD, research assistant professor of Urology, have discovered that aberrant activation of a specific oncoprotein drives key tumor promoting changes in the prostate tissue microenvironment during cancer progression, according to a @NorthwesternMed study published in @NatureComms.
https://t.co/uXNzaS6CXf