Very excited to share our preprint on the multi-state kinetics of the syringe-like injection mechanism of Tc toxins. Great collaboration between the Raunser @Intein @mpimoph, Seidel @HHU_de, @enricabordignon@sciences_UNIGE and Dong @harvardmed labs.
https://t.co/lbaE6NVtGX
1/3
Pro-IL-18 is trapped by caspase-4 active site to be cleaved - I am proud to present paper that came out in Nature today by Pascal Devant @pascal_devant from Kagan lab @jkagan1 and Ying Dong @Ying70337209 from my lab. https://t.co/SL90QogPmf
@TobiasRaisch @mpimoph Gongrats Milena and Tobi! Great to see you thrive as project group leader! Looking forward to see more membrane protein structures in the future😍
@Intein and I wrote a "Research Briefing" about our recent @NatureSMB article on the molecular mechanism of phosphate release from #actin filaments.
Check it out here: https://t.co/oD8KDDCgUP
We even got inspired by a classic movie for our title 😉
Want to know what a single-residue substitution does to your favorite protein?
Together with @TobiasRaisch we wrote a tool to easily visualize pathogenicity scores from the @GoogleDeepMind#AlphaMissense paper: https://t.co/wFKihBtLT2
We hope you find it interesting :-)
Our work on the peroxisomal AAA ATPase Pex1p/Pex6p has been published in @NatureComms. Congrats to @RuetterM and our co-authors! Discover how this ATPase processes its substrates in our manuscript. 👉 https://t.co/Gfv2Qt4OSR
@uni_muenster@UK_Muenster#CryoEM#Peroxisome
Huge congrats for a great PhD project and an excellent viva to our, now @IMPRS_LM alumnus, Patrick @Pat_Guenther from the @Intein lab! We wish you all the best for your next project!!
So happy to have successfully defended my PhD. Many thanks for the constant support by @Intein at @mpimoph. I am so grateful for all my colleagues throughout my time in Dortmund. Looking forward for future challenges🥳
Congrats to @Pat_Guenther on the very successful completion of his #doctoralthesis with the title
"Structural Investigation of #Cholesterol Homeostasis and Bacterial #Toxins" in the @Intein group #cryoEM
Check his latest publication in @PLOSPathogens
https://t.co/y1cXtL3l8Y