Many congratulations Manju Ojha @Manju_Shree90 who successfully defended her PhD thesis today! The lab is proud of your achievements Dr. Ojha! Wish you all the best for your future endeavors! #PhD, #RNA, #UMBC, @UMBCChemistry
Excited to share our most recent article on Picornaviral IRES. Here, we determined the crystal structure of Type I IRES RNA (domain V) and identified structural homology among eIF4G-binding domains of different IRES types. https://t.co/Hjrsq9UiNY
@KoiralaLab@KrishnaNaba@UMBC
New paper alert! https://t.co/4V7BV7CV0Z Congratulations to all contributors. #RNA@UMBCChemistry@UMBC. Stay tuned for more results from the lab on IRES structural biology.
New paper alert! Congratulations to Manju Ojha et al. We have shown how structural plasticity of RRE modulates nuclear export of HIV -1 RNAs.
Mutation-driven RRE stem-loop II conformational change induces HIV-1 nuclear export dysfunction https://t.co/OHtdXfh32k
We are excited to report the discovery of TIGRs, a widely-occurring RNA-guided system found in bacteria and their viruses. TIGRs consist of a peculiar repeat region which is transcribed into RNA and processed into multiple guide RNAs to direct TIGR-associated proteins to their DNA targets. https://t.co/ketXqFVQqw
We created SynthID, a robust digital watermarking technology to tag & identify AI-generated content. Now we’re open-sourcing SynthID-Text so developers can use it to embed & detect watermarks in text outputs from their own LLMs. Published today in @Nature https://t.co/0gKcjoNHqS
BREAKING NEWS
The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”
Wonderful news! Parafilm M rules!
Very well-deserved recognition after helping so many other #NobelPrize winners achieve their breakthroughs! Congratulations @ParafilmM
BREAKING NEWS
The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.
We’re presenting AlphaProteo: an AI system for designing novel proteins that bind more successfully to target molecules. 🧬
It could help scientists better understand how biological systems function, save time in research, advance drug design and more. 🧵 https://t.co/lx35RvplFr
Thrilled to share a pre-print describing an elegant solution to overcome target size limitation of single particle #cryoEM, where we demonstrate high resolution (2.3 – 2.5 Å) structure determination of small (~20 kDa) ordered proteins using cryoEM! https://t.co/FwLVozpT8G
RT appreciated:
We have an open #PhDposition. Join us in Umeå, 🇸🇪 to explore the mysteries of virus-infected cells using cryo-ET, biochemistry and cell biology.
Application deadline 17 December. More info: DM or read here:
https://t.co/bUNqsdxnTy