Uncalled4—new, open-source software developed by @mike_schatz, @vikshiv1, @samkovaka, @pwhook, @timp0, @RohamRaz, & more—improves scientists’ ability to detect genetic modifications that control gene activity. Learn more: https://t.co/yMt2XqwUbW
Jack received two results indicating a Cancer Signal Detected, with a predicted head and neck origin. Imaging and testing couldn’t find cancer initially. Second test led to a confirmatory PET scan, concluding a stage I squamous cell carcinoma diagnosis.
https://t.co/rQw0ytPNsc
Today begins a new chapter for GRAIL as an independent, publicly traded company. We will be listed under $GRAL on @Nasdaq as of the market open June 25. Learn more: https://t.co/jEeH4qJ3pl
Very excited to announce "Uncalled4 improves nanopore DNA and RNA modification detection via fast and accurate signal alignment" by @samkovaka et al. https://t.co/nnn3CMLWkr
Yet another patient testimonial! Rich received a positive head and neck cancer signal which was later confirmed.
The overall sensitivity for participants of a study with head and neck cancer was 85.7% #MCED
https://t.co/m4IBzIwcEX
The conventional way of classifying metastatic cancers according to their organ of origin is denying people access to drugs that could help them.
We need radical changes in how medical oncology is structured, conducted, and taught https://t.co/NOm19n4ZL1
Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent immune response against a distant tumor. @yerinchen led the charge w/ help from @DjenetBousbaine, @VeinbachsA, @BelkaidLab. @ScienceMagazine 1/26
https://t.co/bgW3C7CJgh
How does multi-cancer early detection work?
Amoolya Singh explains the genomics of cancer in the latest episode of our podcast, #TheCancerSignal. Listen on your podcast platform or here: https://t.co/vXrzuxNKOT
What an amazing resource published this week. The most comprehensive deeply sequenced methylation atlas of normal human cell types. Kudos to scientists at university of Jerusalem and my colleagues at @GrailBio
We are not limited to diagnostics here. Nanoparticles could be used to deplete cfDNA-induced inflammation (more evidence needed here) (2/2)
https://t.co/mX5J941wbN
I've been really fascinated by the growing evidence of cfDNA's relevance to autoimmune disorders. Here Che et al. show the potential of shallow cfDNA sequencing as a diagnostic and prognostic biomarker (1/2)
https://t.co/SzGQfsY4An