Samie Jaffrey

[Ronald Breaker @RonBreaker]

Here's the 2018 version of the '#Riboswitch Diversity and Distribution" poster whose 2017 original was published by @RNAJournal. Updates include SAM-VI, #ppGpp, and PRPP riboswitches, and x-ray structures for guanidine-I, -II and -III. Print it, hang it! https://t.co/4kQ3CP02UK

[Samie Jaffrey @SamieJaffrey]

@RNA3DHub Cool paper on a small molecule targeting and binding a structural RNA element. Another example documenting that therapeutic targeting of RNA with small molecules could become a common approach for disease treatment.

[Nature Cell Biology @NatureCellBio]

A new collection on organoid research is now available! Covering recent reviews & perspectives, research articles, methods & protocols from Nature research journals https://t.co/BWmieMIqWR

[Samie Jaffrey @SamieJaffrey]

@TheSilverLab Really interesting study that provides first link between RNA granule/stress granule pathway and intellectual disability. Highlights importance of RNA granule assembly mechanisms for human disease.

[Samie Jaffrey @SamieJaffrey]

@RNApreprints Nice evidence for 2’-O-methylation as a new type of epitranscriptomic modification of internal nucleotides in mRNA.

[Samie Jaffrey @SamieJaffrey]

Very nice model for how m6A is targeted to pluripotency-regulating genes. m6A writer complex is recruited to gene promoters via SMAD2/3. Maybe be relevant to m6A effects in cancer as well. https://t.co/AfBgUMiUIO

[Emere Demir @EmereDemir]

@RNApreprints Wow! A very important and neglected concept.

[Samie Jaffrey @SamieJaffrey]

@RNApreprints Beautiful FISH results and a nifty simple protocol that doesn't require Stellaris probes. This should lower the barrier for performing FISH experiments.