Sam Rose

[Joseph Minhow Chan, MD, PhD @jmchan88]

🎉Exciting News!🧬🔬 I’m starting a computational biology lab at Memorial Sloan Kettering Cancer Center in NYC! We're hiring at all levels to study how histological transformation and other forms of lineage plasticity drive progression across cancer types! https://t.co/oopDqJVNrZ

[The Maze Lab @themazelab]

https://t.co/hCJxxKiMw8
Pleased to announce our lab's new preprint, led by the fearless Amni Al-Kachak, investigating roles for histone H3 serotonylation dynamics in dorsal raphe nucleus in the regulation of stress-induced gene expression and behavior 🧵

[dana_peer @dana_peer]

Thrilled to share our new paper, jointly with Sasha Rudensky, spearheaded by Ari Glasner, Sam Rose and Roshan Sharma. While deleting genes is the current rave, this paper shows the awesome power of deleting entire cell types, T-regs in this example:
https://t.co/Yxkjzm4FNe

[Cell @CellCellPress]

New Resource online now! Perturb-map combines CRISPR pools, multiplex imaging, and spatial transcriptomics to enable the identification of genetic determinants of tumor composition, organization, and immunity
#sciencetwitter #genomics #CRISPR
https://t.co/GQf0pNtVJ5

[Maxime Dhainaut @MaximeDhainaut]

Our work establishing Perturb-map for spatial functional genomics is officially out @CellCellPress :
Spatial CRISPR genomics identifies regulators of the tumor microenvironment
https://t.co/d6eC7OF5Qd

#CRISPR #cancerimmunology
Summary of the work in the thread below 👇(1/8)

[Mount Sinai Tisch Cancer Center @TischCancer]

New pub from lab of Brian Brown, PhD: Perturb-map enables CRISPR genomics with spatial resolution and identifies regulators of tumor immune composition https://t.co/hV49LLkn7M
@MaximeDhainaut @AkturkGuray @OlaWroblewska @MiriamMerad @BhardwajLab @SinaiImmunol @IcahnMountSinai

[Maxime Dhainaut @MaximeDhainaut]

Delighted to share our latest work @Brown_lab1, developing Perturb-map: a platform enabling CRISPR genomics with spatial resolution in tissue sections @SinaiImmunol @IcahnInstitute @SinaiGenetics
https://t.co/gXm20dTlS8
A thread!👇(1/12)

[Immune Regulation News @Immune_News]

📰 Dr. Brian Brown (@Brown_lab1) at @IcahnMountSinai and colleagues have published a resource in @NatImmunol, which delineates the cis-regulatory elements controlling miRNA signatures of the #ImmuneSystem.
https://t.co/AceTrP4xnN

[Lipschultz Precision Immunology Institute @SinaiImmunol]

#Priismpapers
Check out te latest from ⁦@Brown_lab1⁩ in ⁦⁦@NatImmunol⁩ !
Sam Rose and colleagues established an atlas of microRNA expression and regulatory elements in murine immune system https://t.co/tCyy2s6xsO

[Trevor Bedford @trvrb]

Important new study by Wibmer et al (https://t.co/q6150ahSCz) of neutralization by convalescent sera on wildtype vs 501Y.V2 variant viruses circulating in South Africa. It shows that mutations present in 501Y.V2 result in reduced neutralization capacity. 1/10

[Florian Krammer @florian_krammer]

1) The biggest worry for vaccines about the new UK variant is the N501Y mutation in the receptor binding domain. This is also a mutation that appears when SARS-CoV-2 is mouse adapted. A paper looking at that found....

[Sam Rose @Srose89]

@her27169186 ♥️♥️

[Sam Rose @Srose89]

@her27169186 🧐

[Sam Rose @Srose89]

@her27169186 @chunkbardey I love those

[Sam Rose @Srose89]

@her27169186 @ThyArtIsMemes 😢

[Prof. Akiko Iwasaki @VirusesImmunity]

How does the immune system work? Will there be #COVID19 vaccines? @BioRender & I put together ‘immunology 101 tweetorial for non-immunologists’. @jerryguartist, @shizaoki, @JungHeeSciViz also made this accompanying video. Please share widely! (1/n)

https://t.co/eoNOqz2CXr

[Sam Rose @Srose89]

@her27169186 @Keefler_Elf One day...

[Sam Rose @Srose89]

@her27169186 @ryanharrry 😮

[PFT Commenter @PFTCommenter]

Tomorow's @PardonMyTake is maybe one of the most important sodes weve ever done: Dr Anthony Fauci- the Director of NIAID in charge of leading our countrys response to COVID-19 virus discusses what steps we need to take. AWLs will save the World https://t.co/da9VpJlXc0

[Florian Krammer @florian_krammer]

THREAD. 1) I am going to put up my slides here from an overview presentation I gave at Sinai. I hope you find it helpful.