Tao Liming

single cell genomics, cell lineage tracing in development and cancer evolution

[Tao Liming @Taoliming]

@QingZhangLab AI powered Editor

[Tao Liming @Taoliming]

Too little MECOM causes bone marrow failure, too much -> AML, Well put! @RichardVoit

[Richard Voit @RichardVoit]

Too little MECOM causes bone marrow failure, too much -> AML. We wondered why. Turns out that MECOM (and friends) finely tunes the expression of an essential HSC transcriptional network that gets hijacked in leukemia. Proud of our whole team: https://t.co/pAPYYUhIzx

[Tao Liming @Taoliming]

@bloodgenes @NatImmunol @RichardVoit @fulong_yu @broadinstitute @mateusz_ant @tjflemin @liamcato @xiaotianliao @LWahlster @neuron81 @DFBC_PedCare @DanaFarber @BostonChildrens Thanks @bloodgenes Great teamwork!

[Vijay Sankaran @bloodgenes]

Wonderful to have our paper on a MECOM-regulated gene network in human hematopoietic stem cell maintenance and leukemia published in @NatImmunol! Terrific work from our group led by @RichardVoit, @Taoliming, and @fulong_yu:

https://t.co/JLAzHypHYq

[Christopher Smillie @cssmillie]

The Smillie Lab opens March at @MGHMedicine! We develop methods (wet/dry) to understand microbial life on the human body #microbiome #singlecell #evolution #deeplearning. Hiring grad students, postdocs, and RAs @harvardmed @broadinstitute. Please share! https://t.co/uKyEHqvaLe

[HHMI | Janelia @HHMIJanelia]

A new imaging method follows young neurons in a developing zebrafish as they travel across the embryo and organize themselves into circuits. Read the latest work from Philipp Keller’s lab, published today in @CellCellPress. https://t.co/BlpElvHKrP

[Tao Liming @Taoliming]

Cool

[MIT Biology @MITBiology]

In this Technology Feature from Nature, Chris Burge @daSpliceIsRight discusses what it takes to turn a sequencer into a high-throughput instrument measuring protein–DNA interactions: https://t.co/IStkjE13r5

[Nature Biotechnology @NatureBiotech]

Immune-centric network of cytokines and cells in disease context identified by computational mining of PubMed https://t.co/uLLCkeb2K5

[Cell @CellCellPress]

New tool alert! Development of intron seqFISH allows in situ profiling and visualization of nascent #transcription at the #single_cell level, revealing spatial and temporal features of the nascent transcriptome https://t.co/QaX3GHu2i2 @LongCai_Lab @Caltech #techdev

[Lior Pachter @lpachter]

Supp Fig 3. shows an 8 sample (some human, some mouse, some mixed) multiplexed experiment. The color gradients hint at an exciting finding, namely that tag # is a proxy for cell size, thus opening up the possibility of a new mode of single-cell measurement along w/ scRNA-Seq.

[allen institute @AllenInstitute]

See how the #openscience cell lines and plasmids that are available through our #AllenCellCollection can help researchers to see inside of healthy human cells with unprecedented clarity. #Crispr

[Dominic Grün @dominic_grun]

Our new FateID method predicts lineage probabilities in stem cells from subtle transcriptome modulations - going beyond clustering! It enabled the discovery of a common progenitor population of B cells and pDCs! https://t.co/HfyPYHk1RA

[Nicolas Robine @notSoJunkDNA]

Intra-tumour diversification in colorectal cancer at the single-cell level
https://t.co/kGzo0IOG3D

[Sorek Lab @SorekLab]

Protein-Injection Machines in Bacteria
https://t.co/jXmMEMKQNF
Review by Jorge Galan & Gabriel Waksman

[Karen Miga @khmiga]

I am proud to announce the first linear map of a human Y chromosome centromere is now published. https://t.co/fDazzMa8O8. Congratulations @mitenjain @HOlsenUCSC @AkesonUCSC @hwillardX @BenedictPaten @nanopore @ucscgenomics @ucsc_nanopore

[Broad Institute @broadinstitute]

Skin color “is not a binary trait,” @genetisaur notes in @NatGeoMag article. “It’s a quantitative trait, and everyone has some gradient on this spectrum.” https://t.co/UrBj6UR87l

[Tao Liming @Taoliming]

@USA_China_Talk Dear Ambassador, we applied our J VISA from different Embassy. I have already received my J1 VISA from Tel Aviv a week ago. My wife is still waiting for hers J2 from GuangZhou. Could you expedite her case AA007MZ9S? We have already missed our initiate date.

[Tao Liming @Taoliming]

@pdhsu @salkinstitute @CellCellPress Congrats!

[Georg Seelig @seeliglab]

Our approach to making single-cell RNAseq more affordable and high-throughput is out: https://t.co/7RkieTEjae Fantastic work by @dna_rosenberg @RocoCharlie @annabiosys @SMukherjee89 @paul_sample_ and collaborators @AllenInstitute and Pun lab.

[Wellcome Sanger Institute @sangerinstitute]

We are deeply saddened to announce the death of Professor Sir John Sulston, founding director of the Wellcome Sanger Institute. He was a great scientific visionary and leader who made historic contributions to science.