Our analysis of multiple CH types provides insights into the underlying mechanisms of a range of CH types and detail characteristics of potential relevance for disease risk.
@DerekWBrown_1@liamcato@ZhaoDylan @NCIChanock @jrbperry@bloodgenes#NCI_ITEB
https://t.co/JaJVgh9bz0
Great to see our preprint out examining shared and distinct genetic causes of different types of clonal hematopoiesis! Terrific collaboration with @DerekWBrown_1, @liamcato, @ZhaoDylan, @jrbperry, @mitchiela:
https://t.co/lDELAo8Y7t
Are you interested in how we can learn more human biology by integrating #singlecell genomics and #GWAS?
Please check out our preprint:
#V2F mapping at single-cell resolution through network propagation
https://t.co/KDfJbOdLaL
Led by @fulong_yu! A short 🧵 (1/n)
@bloodgenes Thank you Vijay! Wouldn’t be remotely possible without you. So grateful for great mentorship and leadership. As well as being able to work with my great colleague Jiawei Zhao.
Also included is @bloodgenes and @jyoti_nangalia’s further elucidation of the heritability of MPNs by looking at a rare genetic variant found in the UK biobank presented by @liamcato, recipient of #ASH21 Abstract Achievement Award. #mpnsm
Delighted to have our pre-print, "A genetic disorder reveals a hematopoietic stem cell regulatory network co-opted in leukemia", led by @RichardVoit, @Taoliming, and @fulong_yu in a great collaboration with #AvivRegev posted on @biorxivpreprint: https://t.co/ZwzEQ5USjf
🧵👇
In this, we show measured nucleosomes have a significant inverse effect in-vivo upon anti-factor Xa activity (a measure of LMWH effect), suggestive of their interference with heparin's MOA on anticoagulation in severely injured burn patients.
Terrific to have our latest preprint out in @medrxivpreprint led by the amazing team of @la_liggett, Liam Cato, @J__Stock, and @AlexBickMDPhD: "Clonal hematopoiesis in sickle cell disease"
https://t.co/YQMElu2asX (Thread .. 1/n)
Wonderful to have the opportunity to present at the 20th ISBI Congress on both heparin resistance and prevention in burn injury. But more so, to hear the engagement and work that everyone is doing. Continually grateful to all those that make this possible @nmoiemen@scarfreeworld