ChenLabToledo

Cell biologist and Associate Professor @utoledo studies the role of actin cytoskeleton and calcium signaling during cytokinesis. Alumnus of @UTAustin @PKU1898

[Bruker Fluorescence Microscopy @BrukerFM]

🔬 Cell-type-specific GCaMP6 miniscope imaging of a freely-behaving mouse brain. ~1,200 excitatory CA1 hippocampal neurons were imaged during active behavior over months.

Courtesy of the Schnitzer Lab, Stanford.

#MicroscopyMonday #Neuroscience #Lifescience

[ChenLabToledo @Turfee]

@foodskop @UWMadison @uwgenetics @UW_LSC @uwmadisonarts Congratulations!

[Cell @CellCellPress]

In the latest issue! Calcium signaling in plants: Universal and unique paradigms https://t.co/cnNRXLrj7J

[Cell Press @CellPressNews]

Protocol to identify mechanosensitive nuclear proteins using tunable actomyosin contractility and proximity biotinylation in mammalian cells @StarProtocols #bps2026 https://t.co/rZpfYRZtJZ

[American Society for Cell Biology @ASCBiology]

Step-by-step protocol and reproducibility
Generate iPSC-derived 3D neurospheres for neuron–glia studies.

Date: March 25 | Time: 12:00 pm ET
Free
Register: https://t.co/RRAB9ObkuD

[American Society for Cell Biology @ASCBiology]

Cell Bio 2026 is built by scientists, for scientists—and it starts with your ideas.
Submit a scientific session proposal and help shape the program.
🗓 Deadline: February 22, 2026

Submit Now: https://t.co/kqoBZWGrej

[Journal of Cell Biology @JCellBiol]

.@richa_rikhy lab @IISERPune show Drosophila Missing-in-Metastasis (DMIM) (also called MTSS1) promotes Rac1 mediated branched actin network formation & endocytosis to drive rapid, cyclical plasma membrane remodeling during embryonic syncytial divisions https://t.co/3UhIP8YpBZ

[Žiga Avsec @Avsecz]

AlphaGenome is out in @nature today along with model weights! 🧬

📄 Paper: https://t.co/1fHzSPiY1x
💻 Weights: https://t.co/z6JWLT4Mpv

Getting here wasn’t a straight path. We sat down @googledeepmind to discuss the story behind the model, paper & API: https://t.co/cT8CiXfnxQ

[J Cell Science @J_Cell_Sci]

Cell biology for a sustainable future – a call to action from Camila Costa, Eliott Flaum, Delfina Hlashwayo @DHlashwayo, Marie Jacobovitz, Guillermina Kubaczka, Samuel Lovat, Eliya Milshtein, Hanna Szafranska @HannaSzafransk1 and Soraya Zwahlen.
https://t.co/baHaZniznh

[Journal of Cell Biology @JCellBiol]

Review: Siqi Deng, Zhiqiang Yan et al. @hkust summarize the physiological functions and structural basis of OSCA/TMEM63 proteins, positioning them within a mechanosensitive ion channel superfamily. https://t.co/qvVywapHBL

#Physiology #Neuroscience #Mechanobiology #IonChannels

[Journal of Cell Biology @JCellBiol]

New research from Lee, Higgs et al. @GeiselMed shows how #INF2, a key #actin regulator, is activated by calcium-calmodulin and free actin monomers. Actin-binding proteins like profilin and thymosin aren't just helpers - they directly tune INF2 activity. https://t.co/ZYPcpXmC4S

[eLife - the journal @eLife]

This study presents new tools for measuring the intracellular calcium concentration close to transmitter release sites, which may be relevant for synaptic vesicle fusion and replenishment.
https://t.co/8fuhu8b9hz

[Michael F. Chiang, MD @NEIDirector]

@NIH has launched the nation’s first dedicated Organoid Development Center to accelerate human-based research and to complement animal models. The center will support new 3D tissue models to study disease, drug response, and human biology.

https://t.co/UWONUA5rC3

[Journal of Cell Biology @JCellBiol]

Spotlight: Ivan Radin discusses new work from Ryken et al. (https://t.co/vBv4LCdtIl) which shows how localization and function of autoinhibitory calcium ATPases maintains the strength of the tip-focus Ca2²⁺ gradient during polarized plant growth. https://t.co/Sl88p6JjJ3

[eLife - the journal @eLife]

This study presents new tools for measuring the intracellular calcium concentration close to transmitter release sites, which may be relevant for synaptic vesicle fusion and replenishment.
https://t.co/8fuhu8b9hz

[American Society for Cell Biology @ASCBiology]

From MBoC... Tired of hand-annotating cell images? Ajit Joglekar and colleagues introduce Cell-APP, a tool that automates creating training data for cell-segmentation models—speeding up workflows and helping labs build models that fit their needs.

🔗 https://t.co/nP0EIvC81j

[J Cell Science @J_Cell_Sci]

Leanna Owen, Margot Riggi, David Drubin, Janet Iwasa and Yidi Sun use molecular animation to depict the full progression of CME in budding yeast, with an accompanying Cell Science at a Glance article and poster.
https://t.co/Lh64Kr5MC3

[nature @Nature]

KJ Muldoon, at less than a year old, was the first known person to receive a personalised CRISPR-based genome-editing therapy

He is part of Nature’s 10, a list of people who shaped science in 2025

https://t.co/pWXgo7OSBT

[Cell Biology J-Club @cell_club]

Endoplasmic reticulum disruption stimulates nuclear membrane mechanotransduction
https://t.co/519NUr6fxv

[Journal of Cell Biology @JCellBiol]

.@ElMossadeq, Dumont et al. show that an interkinetic envelope surrounds chromosomes between #meiosis I and II in #Celegans oocytes. https://t.co/FkwBwWyMiK

📕 From The Year In Cell Biology: https://t.co/lncOB1KYYN

#CellBio2025