NK cells, immune cell therapies. From bench to bedside. PI: Prof. Evelyn Ullrich @FCI_health @goetheuni @UK_Frankfurt Tweets: lab members. RT≠endorsements
Fantastic #NK cell & #ILC meeting in Lyon 2024 🇫🇷 A big thank you to the organizers @dgfi_org and huge congrats to Alina for the abstract & Tobias for the oral presentation awards🎉and to all awardees and great speakers 2024 @CerwenkaLab@EricVivier1@MalmbergLab@KathyHsuLab
Great time at joint 🇫🇷🇩🇪 #NK#ILC meeting in Lyon! Honored to receive an oral presentation award. Fun catching up with old friends from 🇸🇪 🇺🇸 and meeting new ones. Huge thanks for an insightful meeting! Think we all found gold of knowledge at the end of the rainbow! 🐓🌈🧫🧬🍇😉
Congratulations!
The #DGGTeV proudly awards @TobiasBexte representing the @Ullrich_Lab at @goetheuni the #PoQ2024Q2 for harnessing SB-technology for virus-free engineering of primary NK cells to improve their basal anti-cancer function via CAR introduction
https://t.co/tRehIRDi2j
🔍 Highlights from Keynote Lecture 1 🔴
No one less than the Nobel Prize Winner 2018, James P. Allison, on immune checkpoint blockade therapy at #ECI2024 🎉
🔑Key points:
💡Anti-CTLA-4 therapy creates a “hot” tumor, which does not happen with anti-PD1 therapy.
🔬Anti-CTLA-4 therapy results in a phenotypical switch inducing ICOS+ Th1-like CD4 T cells. ICOS/ICOSL pathway is necessary for optimal anti-tumor response.
A profound thanks to James P. Allison for his groundbreaking contributions 👏👏
#Immunology #Dublin
Delighted to welcome @romeerizwan and thanks for his fantastic presentation on outstanding work in the NK cell field. We had a great scientific exchange at @goetheuni@JhKmann @FCI_health @UK_Frankfurt
I had an amazing time visiting and giving a talk at Frankfurt University @goetheuni hosted by @EvelynNKlab2012 who is doing some cutting edge NK cell work. Also was fun to meet faculty and students there.
Inspirierendes Summer Networking Event 2024 des FIT-Mentoring Program @goetheuni@UK_Frankfurt ☀️Herzlichen Glückwunsch auch den neuen Fellows des @BMBF_Bund geförderten Advanced Clinican Scientist Programm und des @dfg_public geförderten Clinican Scienist Programms INDEEP!👩⚕️🔬
Exciting work in the field of #NKcells - one should definitely read it! Congratulations to @MalmbergLab and coworkers! 🎉 @herknet @AlinePfefferle @AmirHorowitz et al!
Thrilled to announce the publication of our latest research in Nature Immunology. Joining forces with 20 laboratories in Europe and USA, we identified the three prominent NK cell subsets in human: NK1, NK2, and NK3: https://t.co/VMPTPpiLOV
Congrats to @lab_rezvani and team on this seminal work towards clinical translation!🎉 So great to see how improved #CAR signaling enhances #NKcell function! 💪
Many congratulations to our Dr. Sunil Acharya @sunilacharya13 for his exciting research on CD70-targeting CAR NK cells, published in Cancer Discovery! Sunil and his co-authors showed that the incorporation of CD28 costimulation, which is normally absent in NK cells, in the CAR construct improves efficacy of CAR NK cells via the LCK/CD3ζ/ZAP70 pathway. Sincere thanks to our collaborators for their invaluable contributions. We’re excited about the promising clinical trials ahead! @MDAndersonNews #CancerResearch #Immunotherapy #CAR_NKCells @kchenken@UH_NVLab
Cutting-edge research environment #KindPhilipp2024! Many thanks to the organizer!!🙏💪Well-deserved talks: EGFR-CAR NKs in solid tumors w/Lisa Marie Reindl, B7-H3-CAR NKs w/Sophia Thul, mechanisms of CAR-NK cancer cell death w/Alina Moter, CD123/CD33-CAR NKs w/Fenja Gierschek!👏
Paper alert!🧬🎉#SleepingBeauty is awake in primary #NKcells!
So happy to see our work on safe & efficient non-viral CAR NK cells published @MolTherapy! Big shout out to all collaborators especially Zoltán Ivics & all co-authors! https://t.co/MHf67klIbm
@FCI_health @ASGCTherapy🧵
Excited to go to @C_IMT#CIMT2024 to talk about the concept of CAR-engineered NK cells today, and to see our work on non-viral #SleepingBeauty CAR NKs published! Fantastic work by @TobiasBexte and big thanks to all collaborators! Is the future virus-free?@FCI_health @UK_Frankfurt
Engineering of potent CAR NK cells using non-viral Sleeping Beauty transposition from minimalistic DNA vectors https://t.co/Ry6vnmCCuU #genetherapy#celltherapy