As Mitochondrial Disease Awareness Month continues, we're highlighting another aspect of mitochondria that people typically don't get to see.
Mitochondria are dynamic. They move, change shape, fuse, divide, process information, and send signals that are important for our health.
This short video gives you an up-close look at mitochondria in motion.
Curious about your multi-faceted mitochondria? Here are a few TSEE Substack pieces celebrating their amazing biology:
Discovering How Mitochondria Communicate
https://t.co/Gf5yQsn482
Mitochondrial Terminology Reimagined
https://t.co/qySKg4LlKI
Mitochondrial RNA cytosolic leakage drives the SASP
"these findings uncover a mitochondria-to-cytosol RNA signaling axis that promotes senescence-associated inflammation and may offer new therapeutic opportunities."
https://t.co/9gKOJHgYLv
I'm working on this little ribosome game. You have to build a peptide as fast as you can. Prokaryotes can incorporate 20 amino acids per second. Currently, only the tRNAs work; the amino acids are next.
Interesting new @Cell_Metabolism paper: Excessive vigorous exercise impairs cognitive function through a muscle-derived mitochondrial pretender. https://t.co/JCq8ttoExt
🚨 New from our lab (est. 2020) — now published in Nature Communications!
🧬We uncover a surprising link between the v-ATPaseand mitochondrial function:
Mild v-ATPase inhibition restores cell fitness under mitochondrial mistranslation stress
https://t.co/9rWlgmGblB
(Thread ⬇️)
A beautiful demonstration of individual genes producing multiple proteoforms with different subcellular localizations.
Alternative translation initiation sites generate N-terminally truncated proteoforms that localize to different cellular compartments.
If you want more mitochondrial biology in your life, here is a great series of talks on mitochondrial science over the coming weeks and months
Thank you @MitOtalks !
Doing good science requires the utmost exertion of body, mind and spirit, yet is consistently filled with failure and rejection.
#PhD#phdlife#Scientist#AcademicTwitter
Rodriguez Salazar, @c_eroglu et al. @DukeHealth show that Drp1-mediated mitochondrial fission is necessary for peripheral #astrocyte process formation. Loss of Drp1 induces astrocyte reactivity & disrupts cortical astrocyte organization https://t.co/8gMUXvShFD
Thanks @daphnezohar for hosting me at @PureTechH this afternoon. After working with her and @cngarabedian on @BiotechCH every Sunday for the last ~2 years, it's terrific to see each other in person.