It's so fun to let loose and get creative with @mitchguttman@sofiquinodoz. We developed a great idea and I'm pleased to see my art on the cover of @CellCellPress today. Plus there's more fantastic work from Guttman Lab @Caltech inside.
Our new issue is now out! Featuring the role of Z-form DNA in biofilm formation, the regulation of caste identity in ants, and how cyclic pyrimidines mediate bacterial immunity against phages
#NewIssue#sciencetwitter
https://t.co/bHYEUYp90Q
Congratulations to @LongCai_Lab, @mhofflab, @davidvanvalen, Kai Zinn, and Matt Thomson! These five researchers have been awarded grants from the High-Risk, High-Reward Research (HRHR) Program of the National Institutes of Health (@NIH). 👏
https://t.co/yqw4Qt2IJI
The whole Cai Lab team had a much needed break beneath the trees at Tournament Park. Our resident amateur chef-scientists cooked up an impressive and massive BBQ feast – thank you to everyone who worked so hard to make it a success!
Why are lncRNAs lowly expressed? How can they regulate their more abundant targets? Our paper published in @NatureSMB we explore how these features are balanced to ensure target specificity and robust gene regulation via a spatial amplification mechanism. https://t.co/lvJ2VnSWqs
#ICYMI@jwjach &al @mitchguttman lab show that Xist drives non-stoichiometric recruitment of SHARP/SPEN to inactive X, including @ regions not occupied by Xist via concentration-dependent homotypic assemblies of SHARP required for chromosome-wide silencing https://t.co/5h7pD5vIWG
This series is drop-dead gorgeous sci-viz! Entirely a labor of love - Eric applies 3D wizardry to illuminate some pretty dense concepts in bug anatomy/physiology. Glad there’s room for my paintings in there too. #sciart#scientificillustration#entomology#scicomm@GNSIorg
Really enjoyed creating an illustration of Karl Von Frisch to the excellent 4th installment of this series. Astounding 3D animation of insect anatomy and you can finally find out what the world looks like to a bee!
This illustration by @Wonderstrucksci, inspired by Waddington’s second most famous drawing, shows with remarkable directness how MultiFate’s 3 transcription factors, interacting in combinations, produce a multistable epigenetic landscape.
From October cover
Hot topic #Review by Prashant Bhat, Drew Honson & Mitchell Guttman @Caltech
describing how nuclear compartmentalization controls gene expression
#BiomolecularCondensates#GeneRegulation
https://t.co/9JtYYoYV0m
FREE pdf: https://t.co/XQIs4MioSz
Thanks @CellCellPress for highlighting our work on the cover of this latest issue! Artwork by the amazing Inna-Marie @Wonderstrucksci depicting RNAs scaffolding, recruiting, and placing different building blocks (e.g., nuclear bodies) inside the nucleus 🎨👩🎨👏
Excited to see our paper featured on the cover of the current issue of Cell (@CellCellPress)! On the cover, RNAs scaffold, recruit, and place different building blocks of the nucleus. Artwork by Inna-Marie Strazhnik (@Wonderstrucksci)
Researchers from biologist @MitchGuttman's lab developed a powerful tool that can peer into the world of the cell's genetic material to answer questions about what drives organization of RNA, DNA, and proteins in the nucleus.
https://t.co/3A5nb3TKBY
@base2bit@anshulkundaje@LongCai_Lab@Caltech Thank you! My name's Inna - I created the illustrations in this paper, I'm a professional medical illustrator working with researchers at Caltech.
A visual abstract for our latest publication in Science. Work at @LongCai_Lab@Caltech uncovers nuclear architectures within mouse brains–different imaging modalities form a picture of how proteins, DNA, &RNA interact across neurons. #spatialgenomics#medicalillustration#sciart
Why are lncRNAs lowly expressed? How can they regulate their more abundant targets? In our new preprint we explore how these features are balanced to ensure target specificity and robust gene regulation via a spatial amplification mechanism (https://t.co/rmZdWvmdkX)
Check out our latest work of integrated spatial genomics with seqFISH in the mouse brain cortex, now out in @ScienceMagazine! Congratulations to all authors! https://t.co/WiGl4YL0ra