MR CLEAN NO-IV published in @nejm. Strategy of skipping thrombolytic was neither superior or non-inferior. Pending other trials, clinicians should still give thrombolytic to pts who qualify for rx. Subgroup analysis from these trials will also be useful.
https://t.co/PWAegL8ou4
One of my patient asked about risk of stroke after mRNA covid vaccine before his third dose. This new study gives a reassuring answer https://t.co/5ZiUJ7jJLp
Although the use of IV heparin for stroke has declined in the last 20 years, still useful article on "Heparin resistance" in @NEJM. Still used for venous sinus thrombosis and other thrombotic conditions
August 26, 2021
N Engl J Med 2021; 385:826-832
@WorldStrokeOrg@ESOstroke
Post-stroke pseudobulbar affect is not uncommon. Localize to various regions, not only brainstem. Mechanism is reduced serotonin and dopamine transmission and enhanced glutamate transmission. https://t.co/1OxytL8bin
Here’s the deal: The Delta variant is more contagious, it’s deadlier, and it’s spreading quickly around the world – leaving young, unvaccinated people more vulnerable than ever. Please, get vaccinated if you haven’t already. Let’s head off this strain before it’s too late.