Was fun writing this for September's @IJROBP Gray Zone case; an interesting HPV+ OPC question by @baileynelson92 & Dr. Takiar. A recurring scenario in the TORS era - even as our understanding evolves, Qs remain.
Thanks to @ZHusainMD for the guidance!
https://t.co/m5qNWHfFg3
Big congrats to the head and neck @Sunnybrook team treating our first head and neck cancer patient on the @Elekta Unity MR Linac. Major step to adaptive radiation in this challenge disease.
Delighted to share results from our neoadjuvant immunoradiotherapy trial in #HeadAndNeckCancer, out in @jitcancer
8Gyx3 to GTV + Nivo prior to surgery=
pCR=67%
MPR (<10% viable rumor cells)=86%
Clin to path downstaging=90%
No adjuvant tx
@ChilesResearch
https://t.co/xfeQhWbWT0
🚨 In this seminal RCT done by @imrtlee@MSK_RadOnc @sloan_kettering, the addition of Avelumab to SOC chemoRT in PDL-1 unselected LA-HNSCC did not prolong PFS, the study's primary endpoint.
https://t.co/XYT5ffVaog
@SprakerMDPhD@SchaubMD@CancerConnector@ShaunaRadOnc yeah so limitations of all databases, but for rare diseases not much choice. we chose to train on seer so we could also see that the CSS curves separated and then validate in NCDB since there's only OS data there. RPA seems to validate nicely.
Out now in @JNCI_now (https://t.co/rCHsSXxnef)! @sloan_kettering H&N team’s work on Precision Radiotherapy for HPV+ HNSCC: **30Gy** for definitive treatment! Spear-headed by @imrtlee & Eric Sherman, & and an all-star translational cast (JRF, SNP, TC, & more). #radonc#hncsm (1/N)
Congrats to Ian Poon and the CORE international group pooling 1033 OM patients treated with SBRT so we can further understand outcomes in this potentially curable population
Very pleased to share the results of our RCT on consolidation RT in metastatic NPC changing the paradigm of how we think of treating metastatic disease and altering disease trajectory! #nasopharyngealcarcinoma#radiotherapy#metastasis@JAMAOnc