Zach Pimentel

[Olivier Borkowski @O_Borkowski]

Reduction-to-synthesis: the dominant approach to genome-scale synthetic biology
https://t.co/fMuOQIjLEz

[Michael Baym @baym]

How stable are bacterial genomes as they adapt to an environment? My collaboration with @anuraglimdi, @EvolSys, @RELenski, and @ten_olivier exploring this over 50,000 generations of evolution is out today!
1/
https://t.co/q7WwMo1LvY

[Tom Ellis @ProfTomEllis]

Another exciting new tool to engineer biology from the Jason Chin Lab >>> Establishing a synthetic orthogonal replication system enables accelerated evolution in E. coli | Science https://t.co/jq3sP5nm1A

[NASA @NASA]

It will take years for @EuropaClipper to reach one of Jupiter’s icy moons, Europa. But, it only takes a moment to submit your name to be engraved on a chip aboard the spacecraft before its 1.8-billion-mile journey. Don’t miss out! https://t.co/KnyYulzAee

[Luke Weston @lukeweston]

A feeding electric eel can cause transfection of plasmids from the surrounding environment into nearby organisms - natural, eel induced, electroporation.

https://t.co/8I6kAQVRrZ

[Feng Zhang @zhangf]

Since the discovery of CRISPR-Cas systems, people have wondered if a similar type of system exists in eukaryotes. Today, we report in @Nature the characterization of Fanzor, a eukaryotic RNA-guided system that can be reprogrammed for human genome editing. https://t.co/aKLMMEBRkk

[Michael Booth @DrMikeBooth]

We've developed a method to site-specifically introduce chemical modifications *anywhere* on a plasmid 💪

We used this to generate light-activated plasmids 🔦🧬🧪🧫!

Preprint led by @KhoaChung1

@OxfordChemistry @UCLChemistry @synbioCDT https://t.co/g6dQONyeJy

[Michael Fischbach @mfgrp]

Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent immune response against a distant tumor. @yerinchen led the charge w/ help from @DjenetBousbaine, @VeinbachsA, @BelkaidLab. @ScienceMagazine 1/26
https://t.co/bgW3C7CJgh

[Ming "Tommy" Tang @tangming2005]

How to master baisc Unix sed commands for computational biologists 15 mins a day for 12 days. 🧵
The text file is the king of bioinformatics. Knowing how to wrangle the text files on the command line is critical.

I created this 12-day short course for you for FREE👇

[Fungal Bio & Biotech @FBBiotech]

Unlocking the potential of filamentous fungi with synthetic biology 🧬. New research shows how engineering & computational tools boost growth, yield & tackle purification challenges. #FilamentousFungi
#SyntheticBiology

https://t.co/3cpDoCSUwJ

[Tae Seok Moon @Moon_Synth_Bio]

Great review:
Harnessing synthetic biology to enhance ocean health
by Ting Lu, Jim Collins et al.
@TrendsinBiotech

https://t.co/7EmVfia2T7

[Niko McCarty. @NikoMcCarty]

Watch bacteria swap DNA in real time 🔬

Using new genetic reporters, this paper "uncovers the choreography of conjugation reactions in live bacteria."

The videos are beautiful & show how individual plasmids move between microbes. 🍿

https://t.co/V5RNVmfL8A

[Niko McCarty. @NikoMcCarty]

Add a few nucleotides to the 5' end of a guide RNA:
- Retain on-target editing.
- Reduce off-target editing.

Method to screen 10k-100k+ "extended" guide RNAs finds the best variants. 🔻

Another useful dataset for more precise gene editing models, too.

https://t.co/nLdHGwgRl6

[Clive G. Brown @The__Taybor]

Recover library from Nanopore flow cell whether successful or a fail. Re-run, re-process, don't lose a precious sample.

https://t.co/oG48oL5UoP

[Ming "Tommy" Tang @tangming2005]

1/ My new book 'From Cell line to Command line' is finally here https://t.co/R4bsCE6Io8 Grab it to start transforming yourself to a computational biologist!

A thread on how this book came into being: 👇🧵

[Microbiology Spectrum @JournalSpectrum]

Can the different ways in which we handle bacteria in the lab influence our experimental outcomes via effects on bacterial population genetic structure? This study with Streptococcus pneumoniae suggests the answer is yes. @MicrobeAdapt https://t.co/jVYnzYCnnR

[Josh Tycko @JoshTycko]

New Perspective! The simple premise of much of synbio/genetic medicine is "If we design new DNA, cells will run the code" but unfortunately in reality synthetic transgenes are often silenced over time in cells.

@genegirl007 brought together this big group to discuss ways forward

[Jonathan Jacobs 🧬🦠🕹️🏕️ @bioinformer]

If you're interested in data falsification, data quality and data provenance in #genomics data: check out the talk I gave at AMP in Phoenix. Discussed are some of the fundamental, rarely discussed (IMHO), issues of traceability in #bioinformatics data https://t.co/IMuVzRrev8

[Andreas Peschel @AndreasPeschel1]

Only microorganisms produce #antibiotics? These mollusks have their own gene cluster to synthesize erythromycin! #MargaretMcFall-Ngai, #BaozhongLiu
https://t.co/y2s7OVhUal
https://t.co/P7nwVuXd3N