Excited to share that my primary PhD research project is published in @CellReports !
https://t.co/2fuQpHsyw0
In this study, we show that alternative splicing of IRF7, a critical transcription factor in innate immunity 🦠 , has isoforms with distinct functions. a 🧵..
Discoveries can hide in plain sight. #HHMIInvestigator Steven Henikoff's lab found a surprise in old data: a region of ribosomal DNA producing microRNAs that can be associated with cancer, revealing a new role for part of the genome overlooked for decades: https://t.co/HCf46FYgBi.
You live in luxury. Without scientists, 6 billion of us would not be alive & the rest would live in hell. Remember that
Great choices @brkthroughprize 🏆 Congrats to my colleague @Harvard, Stu Orkin, who won the prize for helping cure sickle cell disease with CRISPR 👏
Stunning new landmark study from #HHMIInvestigator David Reich & team @harvardmed lets us watch human evolution in real time across 10K yrs, & what ~16K ancient genomes reveal is striking: Natural selection didn't stop when civilization began — it sped up: https://t.co/ebth0rD8N7
From @TheAthletic: Anne Flower, a 36-year-old ER doctor, loves being the “Batman of medicine.” In true superhero fashion, she leads another life outside hospital walls, breaking world records in ultramarathons.
https://t.co/asyuotltl1
We are proud to share a paradigm-shifting publication from Westlake University in the journal @ScienceMagazine . The study, led by Prof. Xiang-Dong Fu, reveals a fundamental mechanism of gene expression: how cells accurately identify correct splice sites during transcription.
The research challenges the long-held model by discovering an unexpected U2AF cycle.
Please see the details 👉 https://t.co/CVWAhXsRpz
#WestlakeUniversity #Genetics #RNA #MolecularBiology #Science
It’s been deeply rewarding to build this project from the ground up, & watch it grow from an idea💡into a full story with broader implications at the intersection of RNA biology & immunology. Stay tuned for more discoveries in gene regulation, RNA biology & more in the future!��
Excited to share that my primary PhD research project is published in @CellReports !
https://t.co/2fuQpHsyw0
In this study, we show that alternative splicing of IRF7, a critical transcription factor in innate immunity 🦠 , has isoforms with distinct functions. a 🧵..
These findings broaden our understanding of immune regulation, moving beyond transcriptional regulation 🧬 to the fine tuning of cellular immune responses through post-transcriptional gene regulation at the level of alternative splicing..
Tomorrow, in #PreprintClubHub1 Mount Sinai’s Rachel Geltman @RachelGeltman will present a #preprint from @asmita_panthi about the way alternate isoforms of IRF7 differentially regulate #interferon expression to tune response to viral infection. 7⃣ 🎶🤒
https://t.co/2XQjKujYd8