bitsprint

Proud Dad and software engineer for 30+ years, almost ready to (semi) retire to focus on my investment portfolio and live my best life. #hodler

[Professor Avi Loeb @ProfAviLoeb]

I am proud to announce I will be leading a UAP Science Advisory Council to the U.S. Government: Keeping Our Eyes on the Orbs, Not the Audience!

Learn more here: https://t.co/7ibjCz7iK0

[Alex Rives @alexrives]

Together with UC Berkeley we are announcing the laser phase plate - a breakthrough in atomic resolution imaging. This is the brightest continuous wave laser in the world, 100 million times the intensity of the surface of the sun.

Phase contrast plays an important role in microscopy, but it was thought close to impossible for electron microscopy, where it would require interfering with an electron beam. Holger Mueller and Robert Glaeser proposed exactly this using a standing wave laser. It has taken over 15 years to make this a reality. Biohub partnered with UC Berkeley and Mueller to support this work and to engineer and build the technology.

Contrast has been the critical barrier to achieving atomic resolution imaging of the cell. In cryo-electron tomography, a cellular imaging technology that uses electron microscopy, the low contrast makes it impossible to resolve anything but the largest proteins within their cellular context. The laser phase plate removes that barrier.

With advances in AI this breakthrough in contrast will start to open up a new frontier in structural biology, that will allow us to see the molecular machines of the cell, and how they assemble into far more complex and dynamic systems, and understand how they work.

[Tesla Europe, Middle East & Africa @teslaeurope]

Full drive through London, UK 🇬🇧

FSD Supervised is pending regulatory approval

[Tesla Europe, Middle East & Africa @teslaeurope]

FSD Supervised now approved in Belgium 🇧🇪

Rollout will begin soon

[Anthropic @AnthropicAI]

The US government, citing national security authorities, has issued an export control directive to suspend all access to Fable 5 and Mythos 5 by any foreign national, whether inside or outside the United States, including foreign national Anthropic employees.

The net effect of this order is that we must abruptly disable Fable 5 and Mythos 5 for all our customers to ensure compliance.

Access to all other Claude models is not affected.

We apologize for this disruption to our customers. We believe this is a misunderstanding and are working to restore access as soon as possible.

Read our full statement: https://t.co/bwn0sximKZ

[Grok @grok]

Grok Voice Agents are the fastest, most intelligent voice agents available on the market.

[Cambridge University @Cambridge_Uni]

UK AI takes a leap forward.

Zenith – the UK’s largest AI supercomputer – launches at Cambridge, alongside a new Sovereign AI Innovation Lab (SAIL).

From transforming cancer care to fusion energy, collaboration and investment will unlock huge progress in meeting some of the world's greatest challenges.

📸 Nick Saffell

[UK Space Agency @spacegovuk]

We're supporting British companies developing next-generation space technologies. 🛰️

Space Minister Liz Lloyd announced £19 million funding at @LDNTechWeek today, for Cardiff-based @Space_Forge and the @UKI2S fund for early-stage UK space companies. 🚀📈

@SciTechgovuk

[NASA @NASA]

Introducing Artemis III.

Four astronauts. Three launches. Two dockings. One splashdown.

In 2027, the Artemis III mission will practice docking the Orion spacecraft with two lunar landers in low Earth orbit — the capability we need to return humanity to the Moon’s surface.

[Anduril Industries @anduriltech]

Captured by Anduril's network of 400 telescopes deployed around the globe:

The second stage of the Falcon Heavy launch of ViaSat 3-F3 performing a routine thrust event. This produced a spiraled-shaped plume effect, a nominal part of operations for a successful launch of Viasat's latest satellite.

[Tesla Europe, Middle East & Africa @teslaeurope]

FSD Supervised now approved in Denmark 🇩🇰

Rollout will begin soon

[Sawyer Merritt @SawyerMerritt]

Tesla FSD (Supervised) has just officially been approved in Belgium! 🇧🇪

This is now the 5th European country to get FSD approval.

[Lifespan @JoinLifespan]

Today, @lifebiosciences confirmed the first patient has been dosed with an epigenetic restoration drug candidate. An exciting milestone 🚀

Life Biosciences is the OG cellular rejuvenation using epigenetic restoration to reverse diseases of aging. It was cofounded by @davidasinclair, who serves as Chairman

The company’s proprietary Epigenetic Restoration platform utilizes three transcription factors, OCT4, SOX2, and KLF4 (OSK), to restore older and damaged cells to a younger and healthier state. This innovative approach targets a root cause of aging at the epigenetic level, and has the potential to address a wide range of serious age-related diseases

The Phase 1 trial will evaluate the safety and tolerability of ER-100, with additional endpoints assessing visual function. ER‑100 is the first clinical candidate from Life Bio’s Epigenetic Restoration platform, which uses controlled expression of three transcription factors, OCT4, SOX2 and KLF4 (OSK) to restore cellular function by resetting the epigenetic code to more youthful patterns of gene expression

“This is an important moment for Life Bio and for the field of aging biology,” said David Sinclair, Ph.D., Co‑founder of Life Biosciences and Professor of Genetics at Harvard Medical School. “Our research has suggested that aging is driven in large part by the loss of epigenetic information, not irreversible damage. This clinical study represents the first opportunity to test whether restoring that information can ameliorate human disease.”

Beyond ER-100, the company is strategically broadening its therapeutic pipeline to address additional age-related diseases, underscoring the platform’s versatility and transformative potential.

“This milestone reflects years of rigorous scientific development and translational research,” said Sharon Rosenzweig‑Lipson, Ph.D., Chief Scientific Officer of Life Biosciences. “Our preclinical studies have demonstrated that controlled OSK expression can reset epigenetic patterns associated with healthy cellular function, improve tissue performance, and restore visual function in animal models. Advancing ER‑100 into the clinic is an important step toward translating epigenetic restoration into a new class of medicines for age-related diseases.”

Optic neuropathies represent a large unmet medical need. Current treatments primarily address risk factors, such as intraocular pressure in glaucoma, but do not directly target the damage to retinal ganglion cells. As a consequence, the disease often leads to irreversible vision loss despite treatment

Vision loss not only directly impacts patients’ lives, but also increases the risk of loss of independence, damaging falls, and depression and dementia due to social isolation, underscoring the need for disease-modifying therapies.

Beyond ER‑100, Life Bio is developing applications of its proprietary Epigenetic Restoration platform for multiple indications in a variety of organs, reflecting the broad therapeutic potential of this platform.

About Optic Neuropathies Optic neuropathies are a group of disorders characterized by damage to retinal ganglion cells (RGCs), the primary neurons connecting the eye to the brain. Because RGCs do not naturally regenerate, damage results in permanent vision impairment. One such optic neuropathy, open-angle glaucoma (OAG) is a chronic neurodegenerative disease and a leading cause of blindness in older adults

While often associated with elevated intraocular pressure, disease progression frequently continues despite treatment, and some patients suffer from OAG despite normal intraocular pressure. Non-arteritic anterior ischemic optic neuropathy (NAION) is the most common acute optic neuropathy in adults over fifty. It involves sudden, painless vision loss due to insufficient blood flow, for which there are currently no approved treatments

About ER-100 ER‑100 is an investigational therapy in clinical development for the treatment of optic neuropathies including OAG and NAION. ER‑100 is designed to restore function in retinal ganglion cells using Life Biosciences’ Epigenetic Restoration platform, which utilizes controlled expression of three transcription factors, OCT4, SOX2 and KLF4 (OSK), to reset cellular gene expression patterns and restore cells to a more youthful and functional state. ER‑100 is currently being evaluated in a Phase 1 clinical trial. More information can be found at https://t.co/GDRzIctoot (NCT07290244): https://t.co/Jj9cnu2M6w

For more information, visit https://t.co/msih0JTYfF or follow on social media
https://t.co/pEGPJjFjnQ

[ClaudeDevs @ClaudeDevs]

Claude Fable 5 is here. New model generation, new way of working.

Here's how to get started in Claude Code and on the Claude Platform: 🧵

[Seb Johnson @SebJohnsonUK]

London is one of the best places in the world to build an AI company.

@MattEvantic from @EvanticCapital believes the city has everything it needs to become a global AI powerhouse.

My guess it some of the most exciting AI companies of the next decade will come from this ecosystem.

[Kanishka Narayan MP @KanishkaNarayan]

This week, @Keir_Starmer, @RachelReevesMP, @leicesterliz and I have announced a major next step for the UK’s AI trajectory 🇬🇧🚀

*𝐑𝐞𝐢𝐧𝐝𝐮𝐬𝐭𝐫𝐢𝐚𝐥𝐢𝐬𝐢𝐧𝐠 𝐰𝐢𝐭𝐡 𝐀𝐈 𝐜𝐡𝐢𝐩𝐬*

A bumper £1bn+ UK AI Hardware Plan
✅ £750m for a national AI supercomputer, buying British AI chips
✅ A major AMD commitment to UK AI compute startup research (thank you, @LisaSu)
✅ £45m in AI chip skills funding, inc a ramp up of over 500+ brand new AI chip PhDs 
✅ @BritishBBank backing a brand new early-stage UK hardware fund with £150m, @Playground_VC, led by ex-Intel CEO @PGelsinger
✅ Expanded Scaling Inference Lab, so UK compute startups can get rapid validation

*𝐌𝐚𝐜𝐡𝐢𝐧𝐞𝐬 𝐭𝐡𝐚𝐭 𝐬𝐞𝐫𝐯𝐞 𝐮𝐬*

👉🏽 𝑃𝑟𝑜-𝑊𝑜𝑟𝑘𝑒𝑟 𝐴𝐼 𝐴𝑑𝑜𝑝𝑡𝑖𝑜𝑛 𝑃𝑟𝑖𝑧𝑒: Nobel winner @baselinescene will chair a prize that rewards examples of pro-worker adoption
👉🏽 𝐵𝑒𝑠𝑡 𝐷𝑒𝑠𝑖𝑔𝑛𝑒𝑑 𝐷𝑎𝑡𝑎 𝐶𝑒𝑛𝑡𝑟𝑒 𝑃𝑟𝑖𝑧𝑒: @RIBA and @SciTechgovuk will collaborate to reward beautiful and well-designed datacentres
👉🏽 𝐴𝐼 𝐸𝑐𝑜𝑛𝑜𝑚𝑖𝑐𝑠 𝐼𝑛𝑠𝑡𝑖𝑡𝑢𝑡𝑒 𝑙𝑎𝑢𝑛𝑐ℎ: Nobel winner @baselinescene to chair brand new institute, so British workers are first to be supported robustly through AI’s economic impact, with data from 20 large companies
👉🏽 𝐴𝐼 𝐴𝑠𝑠𝑢𝑟𝑎𝑛𝑐𝑒 𝐶𝑜𝑛𝑠𝑜𝑟𝑡𝑖𝑢𝑚: @SciTechgovuk and @bcs will develop robust guidance to grow the UK AI assurance sector
👉🏽 𝑂𝑝𝑒𝑛 𝑆𝑜𝑢𝑟𝑐𝑒 𝑇𝑎𝑙𝑒𝑛𝑡 𝑀𝑎𝑔𝑛𝑒𝑡: OS builder fund, to give 160k+ GPU hours to winners of OS hackathon; OS mentoring scheme to plug OS talent into govt builders; OS Dev Board, bringing 10 young OS developers into Govt AI strategy process

*𝐑𝐨𝐜𝐤𝐞𝐭 𝐛𝐨𝐨𝐬𝐭𝐞𝐫 𝐟𝐨𝐫 𝐀𝐈 𝐣𝐨𝐛𝐬*

🤝 Skills Boost update: 1.7m courses delivered
🤝 Tech First Update: 100k+ young people backed already, 900 scholarss, 2k people on track for sustained AI roles
🤝 AI Early Careers Jobs Alliance: employers + trade unions + young people + govt fundamentally redesigning paths into jobs
🤝 North East Jobs Pilot: AI Growth Zone will support young people not in education, employment, training to get agentic AI jobs, backed by @Accenture, @Microsoft, @sageuk
🤝 Tech First North West Pilot: 5 areas to pilot support for young people at risk of leaving school after GCSEs, getting them onto free AI bootcamps

*𝐀𝐝𝐨𝐩𝐭𝐢𝐨𝐧 𝐭𝐡𝐚𝐭 𝐦𝐨𝐯𝐞𝐬 𝐭𝐡𝐞 𝐧𝐞𝐞𝐝𝐥𝐞 𝐨𝐧 𝐁𝐫𝐢𝐭𝐢𝐬𝐡 𝐏𝐋𝐂 𝐩𝐫𝐨𝐝𝐮𝐜𝐭𝐢𝐯𝐢𝐭𝐲*

⛰️ AI Sector Champion Plans: Major plans to drive adoption, with £200m to back first set of ideas
⛰️ AI Growth Lab: an advisory lab launched to give adopters clear, practical info on regulation
⛰️ Major robotics adoption regulatory innovation initiative
⛰️ Spärck update: expanded £1m scholarship, 50 more PhDs put into AI placements to drive adoption

*𝐍𝐨𝐭 𝐣𝐮𝐬𝐭 𝐭𝐡𝐞𝐨𝐫𝐲; 𝐢𝐧𝐯𝐞𝐬𝐭𝐦𝐞𝐧𝐭 𝐚𝐧𝐝 𝐣𝐨𝐛𝐬 𝐭𝐨𝐝𝐚𝐲, 𝐭𝐨𝐨*

➡️ £2bn from @AMD in UK AI infra
➡️ @nebiusai investing £1.7bn with three major @nvidia deployments
➡️ Major new MoU with @Cisco to support Barnsley use AI in aid of local public servants and to help local NHS
➡️ Major new MoU with @ElevenLabs to support access for those with visual impairments and to secure AI
➡️ Major new MoU with @synthesiaIO to ramp up AI skills and spread opportunity
➡️ @OQC_Tech raising £260m, backed by largest @BritishBBank investment to date
➡️ @reflection_a expanding into UK, hiring 100+ employees within 12 months, and 1,000 within 3 years (welcome @MishaLaskin)
➡️ @Replit announcing UK office opening
➡️ @amazon announcing £1bn investment in Midlands, creating 2,800 jobs
➡️ @Arkdatacentres investing £807m to expand existing campus
➡️ @n8n_io investing in further 200 AI jobs over next 3 years, thanks @JanOberhauser
➡️ @ErosUniverse_, leading Bollywood distributor, investing £265m and backing 3,000 jobs in AI and creative sectors
➡️ @ARLQ_AI investing £45m for UK R&D
➡️ @CocoRobotics announcing UK debut with major Deliveroo partnership
➡️ Midlands Mindforge go live to invest in Midlands firms

[bitsprint @bitsprint]

@SawyerMerritt Would be really interested in learning more about the thermal solution. Any sources? I thought that hadn’t quite been figured out yet

[Seb Johnson @SebJohnsonUK]

The UK Government has just announced a £1.1bn package for AI Hardware!

LETS GO

Here's what is in the package:

> £750m for a national AI supercomputer that will run on a heterogeneous mixed chip system (which @DanAkarca and @CallosumAI are building the future for)

> Of the £750m, £400m will go towards equipping the UK’s AI supercomputer with next-generation chips, which could include buying chips from UK companies OLIX and Fractile

> £120m will fund a new AI Hardware Innovation Programme to give british companies the funding to design, develop and test innovative novel chips

> £20m+ of the programme will expand the Scaling Inference Lab, delivered by ARIA and CommonAI

> £45 million in new support for skills including backing doctoral training and undergraduate bursaries to train more engineers, chip designers and technicians

I caught up with the Minister of AI @KanishkaNarayan to get all the details.

LETS GO amazing news 👏

[Adaptyv Bio @adaptyvbio]

AI has solved software. Biology is the next frontier.
We're hiring across every team at Adaptyv.

We’ve built the best automated lab for protein designers to experimentally test their AI-designed proteins. Today, the most advanced protein design companies run their wet-lab work on Adaptyv, from the biggest biopharmas to frontier AI labs to dozens of virtual biotech startups.

Demand has grown faster than we have, so we’re hiring across the board:

• Bio: Research associates, scientists and lab technicians to develop and run new assays at scale.

• Lab automation: Engineers and interns to onboard new lab instruments and scale our automation infrastructure.

• Software: Product and backend engineers to scale LabOS, our internal lab orchestration platform, our API for agents and the data pipelines that turn messy physical-world data into clean results.

• Partnerships, customer success and operations: Building partnerships with AI & pharma labs, making sure customers understand their data and can run more campaigns, making sure the company operations run smoothly

[Mati Staniszewski @mati]

A very exciting day for @ElevenLabs in the UK.

We just signed an MOU with the UK Government to find new ways to use voice AI to improve access to public services for people across the country!

We are also expanding our presence: doubling headcount & moving to a new office!