Carlos L. Araya

🌳| Explore, Anywhere; 🧬| Modeling, Invitae; 👨‍🚀| CEO, Jungla; 🔬| Genetics, Stanford; 🎓| Genome Sciences, UW; 🌋,🏔,🌊,🏕️| Costa Rica, Norge, Brasil, USA

[Carlos L. Araya @claraya]

Dhanlander and Vericourt hit it hard on the nose pointing out the importance of aligning MVPs, tech de-risking, and strong partnerships for deep-tech startups.
https://t.co/PXoW3cSy3C

[Carlos L. Araya @claraya]

@yacineMTB @karpathy This is hilarious!

[Itai Yanai @ItaiYanai]

Doing good science is 90% finding a science buddy to constantly talk to about the project.

[Carlos L. Araya @claraya]

@stergachislab Really neat work Andrew — congrats!

[Demis Hassabis @demishassabis]

Thrilled to announce AlphaFold 3 which can predict the structures and interactions of nearly all of life’s molecules with state-of-the-art accuracy including proteins, DNA and RNA. Biology is a complex dynamical system so modeling interactions is crucial https://t.co/Gs4GoOB3fD

[Carlos L. Araya @claraya]

@sama Happy Thanksgiving

[Carlos L. Araya @claraya]

@sama You’ve got this. Opportunity.

[Eric Schmidt @ericschmidt]

Sam Altman is a hero of mine. He built a company from nothing to $90 Billion in value, and changed our collective world forever. I can't wait to see what he does next. I, and billions of people, will benefit from his future work- it's going to be simply incredible. Thank you @sama for all you have done for all of us.

[Bill Ackman @BillAckman]

The gov’t has about 48 hours to fix a-soon-to-be-irreversible mistake. By allowing @SVB_Financial to fail without protecting all depositors, the world has woken up to what an uninsured deposit is — an unsecured illiquid claim on a failed bank. Absent @jpmorgan @citi or @BankofAmerica acquiring SVB before the open on Monday, a prospect I believe to be unlikely, or the gov’t guaranteeing all of SVB’s deposits, the giant sucking sound you will hear will be the withdrawal of substantially all uninsured deposits from all but the ‘systemically important banks’ (SIBs). These funds will be transferred to the SIBs, US Treasury (UST) money market funds and short-term UST. There is already pressure to transfer cash to short-term UST and UST money market accounts due to the substantially higher yields available on risk-free UST vs. bank deposits. These withdrawals will drain liquidity from community, regional and other banks and begin the destruction of these important institutions. The increased demand for short-term UST will drive short rates lower complicating the @federalreserve’s efforts to raise rates to slow the economy. Already thousands of the fastest growing, most innovative venture-backed companies in the U.S. will begin to fail to make payroll next week. Had the gov’t stepped in on Friday to guarantee SVB’s deposits (in exchange for penny warrants which would have wiped out the substantial majority of its equity value) this could have been avoided and SVB’s 40-year franchise value could have been preserved and transferred to a new owner in exchange for an equity injection. We would have been open to participating. This approach would have minimized the risk of any gov’t losses, and created the potential for substantial profits from the rescue. Instead, I think it is now unlikely any buyer will emerge to acquire the failed bank. The gov’t’s approach has guaranteed that more risk will be concentrated in the SIBs at the expense of other banks, which itself creates more systemic risk. For those who make the case that depositors be damned as it would create moral hazard to save them, consider the feasibility of a world where each depositor must do their own credit assessment of the bank they choose to bank with. I am a pretty sophisticated financial analyst and I find most banks to be a black box despite the 1,000s of pages of @SECGov filings available on each bank. SVB’s senior management made a basic mistake. They invested short-term deposits in longer-term, fixed-rate assets. Thereafter short-term rates went up and a bank run ensued. Senior management screwed up and they should lose their jobs. The @FDICgov and OCC also screwed up. It is their job to monitor our banking system for risk and SVB should have been high on their watch list with more than $200B of assets and $170B of deposits from business borrowers in effectively the same industry. The FDIC’s and OCC’s failure to do their jobs should not be allowed to cause the destruction of 1,000s of our nation’s highest potential and highest growth businesses (and the resulting losses of 10s of 1,000s of jobs for some of our most talented younger generation) while also permanently impairing our community and regional banks’ access to low-cost deposits. This administration is particularly opposed to concentrations of power. Ironically, its approach to SVB’s failure guarantees duopolistic banking risk concentration in a handful of SIBs. My back-of-the envelope review of SVB’s balance sheet suggests that even in a liquidation, depositors should eventually get back about 98% of their deposits, but eventually is too long when you have payroll to meet next week. So even without assigning any franchise value to SVB, the cost of a gov’t guarantee of SVB deposits would be minimal. On the other hand, the unintended consequences of the gov’t’s failure to guarantee SVB deposits are vast and profound and need to be considered and addressed before Monday. Otherwise, watch out below.

[Rosario3.com @Rosariotres]

Creelo Fideo, somos campeones 🙏🏆

#rosario3 #qatar2022 #mundial2022 #argentina #somoscampeones

[Guardian sport @guardian_sport]

'It will go down as an all-time classic, perhaps the finest World Cup final of them all. It was destined to be Lionel Messi's game in the end, and yet how France and Kylian Mbappé fought.' World Cup final match report by @DaveHytner

https://t.co/3enGSPWwLs

[Carlos L. Araya @claraya]

Tomen que gol!

[Eric Topol @EricTopol]

Just published @ScienceMagazine
A universal influenza mRNA vaccine effective against all 20 lineages of influenza A and B, effective in experimental models
https://t.co/CfABwuE2O0
https://t.co/hyA6lktAgX

[tyler hogge @thogge]

Sorry, who did this? 😂

[Kareem Carr, Ph.D. @kareem_carr]

learning to code in R

[Kresten Lindorff-Larsen @LindorffLarsen]

Adding figures in Word https://t.co/mvXxrXUtjW

[Carlos L. Araya @claraya]

@naval @pdfmakerapp grab this

[ARCHIVED - NASA's Perseverance Mars Rover @NASAPersevere]

I’m back to work, parked between these two beautiful outcrops. Been doing some imaging, weather studies, chemistry experiments and getting a software update too.

Latest pics: https://t.co/Ex1QDo3eC2

[Carlos L. Araya @claraya]

We’ve lost a wonderful scientist with the passing of Dan Tawfik. His creative pursuits brought us to better understand protein stability, robustness, dynamics, and evolvability. His work was an inspiration for many assays that serve modern medicine. https://t.co/mlbomSTJ69

[Trevor Bedford @trvrb]

We generally see more rapid logistic growth of P.1 across individual states as well. These 9 were chosen as those with the most data. All these plots only go to Apr 14, as there is a necessary lag to the genomic data as samples are processed. 4/13