COMBINE Lab@UCL

@[email protected]

The COMputational Biology in Imaging geNEtics lab at @UCL, led by Dr Andre Altmann. Passionate about brains, genetics, and good coffee.

[COMBINE Lab@UCL @CombineLab]

Just in time for AAIC: Our work on investigating the regional spread of amyloid and tau is now available in @Brain1878 With: @NeilOxtoby @WijDr @ilopesalves @LECollij @_JakeVogel_ @FBarkhof @fishpiechicken https://t.co/E765nUkTu5

[COMBINE Lab@UCL @CombineLab]

Join us tomorrow for "The Basics of GWAS in Alzheimer's Disease". Sign up here https://t.co/PknVBRYZqF

[Keir Yong @KeirYong]

4 yr fully-funded PhD* to understand how dementia causes 'brainsight' loss in the largest imaging-genetics study (UK Biobank) & posterior cortical atrophy (visual variant Alzheimer's):
https://t.co/RpG2u9R8FR
* @EPSRC * @BrainAppeal
@drcionucl
@RareDementia
@UCLIoN
@CombineLab

[Neil Oxtoby (Toybox Science) @NeilOxtoby]

Latest paper out of the @EDADS_jpnd project led by us at @CMICUCL is about Alzheimer's disease-sensitive harmonisation, improving on Combat and Neuroharmony (which can erase disease signal). https://t.co/36Ksk7ffWO
FAO: Quantitative Neuroradiology enthusiasts

[COMBINE Lab@UCL @CombineLab]

@wandedob This is wild!

[Paul Thompson @PTenigma]

HOW DOES YOUR GENETIC CODE affect your brain? 💡A new genetic roadmap of the brain (in today's Nature Genetics) reports:
💡100s of genomic loci affect deep brain structures
💡Genetic variants driving brain volume overlap with risk loci for Parkinson's, ADHD, many brain diseases
⚡️Studied N=74,898 people scanned with MRI + GWAS !
⚡️⚡️Polygenic scores now account for up to 10% of the regional brain volume variation in held-out, independent samples not used for discovery; modeling this variance should help future studies
👉👉PDF: https://t.co/wkuILD8gqa
🎈Kudos to Luis García-Marín*, Adrian Campos* + @sudha_md @Frutiloopz @WiroNiessen @jsteinlab @njahanshad @lishenlc @amarquand @mallarchkrvrty1 @StefanEhrlich3 @Roshchupkin @ASaykin @_MariekeKlein_ @AvramHolmes @BFranke_lab @lianne_schmaal @jorsmo @lemaitreh_alien @vdcalhoun + 189 researchers worldwide collaborating for 7 years to do this ! @enigmabrains @chargetiger @uk_biobank ABCD + many more ... 🎈
*co-1st authors

[Wu Tsai Neurosciences Institute @StanfordBrain]

In this week’s podcast episode, Stanford neurologist Michael Greicius discusses the promising future for Alzheimer’s therapies despite skepticism toward the effectiveness of new treatments that target amyloid plaques. #alzheimers #neuroscience

🔗https://t.co/S7f1ctzFqO

[Armin Raznahan @bogglerapture]

Come on in and join us ! @KonradWagstyl and I have a fully-funded 4 yr PhD-ship open thru the super NIMH-UCL (D.C/London) graduate program partnership (https://t.co/nl5kAmCHrP). Bridge Macro<-> views of 🧠 wt neuroimaging & omics (e.g. https://t.co/hjvHCgvmCM). Pls DM/apply ! 😃

[COMBINE Lab@UCL @CombineLab]

🔥Two Lecturer posts available in our Department 🔥 Interested in leading research that combines engineering/physics/robotics/AI with medicine? This is the place! Closing Date: 4th Oct 2024. DM me if you have any questions.

[UCL Medical Physics & Biomedical Engineering @UCLmedphys]

📢 Job Opportunity! We're seeking x2 Lecturers (Assistant Professors) to join us!
This is an exciting opportunity to lead your own group, teach new modules & propose a programme of research of your choice that aligns with Med Phys.
⏲️Deadline: 04/10/24
🔗https://t.co/Gnmttt56Sl

[Brain @Brain1878]

Disentangling genetic risks for development and progression of Alzheimer’s disease

New scientific commentary by Niklas Mattsson-Carlgren https://t.co/BOjJp2zMhf

[UCL Brain Sciences @UCLBrainScience]

Earlier this month @TheLancet Commission led by Prof @Gill_Livingston (@UCLPsychiatry) found that nearly half of #dementia cases could be prevented or delayed by tackling 14 modifiable health & lifestyle factors through our lives: https://t.co/GM2voqbGkY

[UCL Brain Sciences @UCLBrainScience]

AI’s promise in ophthalmology is immense, from handling patient backlogs to improving care. But success hinges on creating the right ecosystem. Professor @pearsekeane, @UCLeye shares his perspective in @OphthoMag.
https://t.co/iw7EXEeS1z

[RikOssenkoppele @RikOssenkoppele]

The figure we all have to learn by heart: The updated Lancet Commission on potentially modifiable risk factors for dementia. #AAIC24

[The Transmitter @_TheTransmitter]

More than 100 neuroimaging researchers, including @furranko, @demwassermann, @memartone, have signed a statement for the leadership of @uk_biobank —in protest of a switch from a data-download to cloud-only access model.

By @callimcflurry

https://t.co/f5mgQSLLUR

[@BrainComms @braincomms]

Estarellas et al. report that an adapted Subtype and Stage Inference algorithm accommodates missing data in multimodal #Alzheimersdisease studies. @mar_estarellas @UCLMIGPOND @NeilOxtoby @jmschott @fishpiechicken @YoungAlexL
https://t.co/2GMz4avfj4

[Luigi Lorenzini @LuigiLorenzini1]

So thrilled to see our Imaging-genetics paper finally out in A&D!! And even more that this is happening during an amazing AAIC, were we first presented these results last year.

... 🎈

https://t.co/HGQXnb0GO3

[COMBINE Lab@UCL @CombineLab]

A few more days left to apply for this PhD opporunity (deadline has been extended to the 21st July)

[Keir Yong @KeirYong]

4 year PhD (apply by 19th July) on visual system vulnerability to neurodegenerative disease.
https://t.co/bcw4TicMJU
Understand susceptibility to 'brainsight' loss in the largest imaging study (UK Biobank) & in visual-led dementia
@drcionucl
@RareDementia
@UCLIoN
@CombineLab

[ConceiçãoBettencourt @saobettencourt]

🚨I'm delighted to share a new publication from the #BettencourtLab team by @megha7murthy et al. on a cross-comparative investigation of #brain #DNAmethylation patterns in #MSA, #PD, #PSP.
https://t.co/4MQMWxmc3R.
Thank you to all involved🙏!
@UCLIoN @MSAtrust #epigenetics

[🟧 Hilary Evans-Newton 🟧 @HilaryAlzUK]

Delighted to introduce Professor Sir John Hardy as Vice President of ⁦@AlzResearchUK⁩ John is a shining light in our field & long time supporter.
Do join me in welcoming him by reading my blog #ForACure https://t.co/rAgSialJzT

[UCL CMIC @CmicUcl]

UCL Medical Image Computing Summer School 2024

[COMBINE Lab@UCL @CombineLab]

or actually... visual-led dementia not 'demention'. 'Covfefe' anyone?

[COMBINE Lab@UCL @CombineLab]

Fantastic opportunity to work on imaging and genetic data in visual-led demention 👇👇👇

[Keir Yong @KeirYong]

4 year PhD (apply by 19th July) on visual system vulnerability to neurodegenerative disease.
https://t.co/bcw4TicMJU
Understand susceptibility to 'brainsight' loss in the largest imaging study (UK Biobank) & in visual-led dementia
@drcionucl
@RareDementia
@UCLIoN
@CombineLab