oconnorlab

We study genomics and viral diseases, especially HIV and now feat. COVID-19, and spend a lot of time wondering what makes viruses cause disease.

[oconnorlab @dho_lab]

Got milk? Interested in citizen science? We are starting to look for grocery store milk and cream from certain dairy processors (can be identified from labeling on the carton) from around Wisconsin as part of our ongoing H5N1 influenza monitoring. DM @dho_lab if interested.

[oconnorlab @dho_lab]

@renegadenarwhal @dylanhmorris @halvorz @ENirenberg What I showed wasn’t UW testing program data, but rather collaborative data from community testing w/ PHMDC.

[oconnorlab @dho_lab]

@renegadenarwhal @halvorz @ENirenberg Yep, soon re: preprint. Meanwhile, see PHMDC’s narrative published today with the same graph. https://t.co/qcdObvr7a7

[oconnorlab @dho_lab]

@km_tsui @dho @tcfriedrich Excellent question, and I don’t know the answer (probably a UW question). We are looking to hire someone quickly to help fill the gap of @GageKMoreno and @KATarinambraun, so it would need to be a really outstanding applicant to make a lengthy hiring process make sense.

[oconnorlab @dho_lab]

Interested in SARS-CoV-2 sequencing? Want to work with a great team including @tcflab? We are hiring a PhD-level scientist to help orchestrate sequencing of viruses as part of an @CDCgov contract.

[oconnorlab @dho_lab]

The job requires lab work and personnel oversight, but could have partial work-from-home options for the right candidate, especially for those who are strong in computational biology. Apply at https://t.co/dVViMS4d71 by June 21 for assured consideration. CC: @dho @tcfriedrich

[oconnorlab @dho_lab]

The job will involve working with @publichealthmdc and our clinical colleagues at @UWHealth to examine sequences from people at high risk: persistent infections, reinfections, and those who become infected despite full vaccination.

[oconnorlab @dho_lab]

New work in collaboration with colleagues at UC-Davis modeling sexual transmission of #Zika virus during early pregnancy. Repeated intravaginal ZIKV challenge was followed by embryonic loss in 2 out of 3 pregnancies. https://t.co/A48TvJ3kuK

[Dave O'Connor @dho]

Excited to see that this review with my friends from @TheDohertyInst and @KirbyInstitute on SARS-CoV-2 assays and animal models is out! https://t.co/oTpgRhz7qk

[oconnorlab @dho_lab]

Been a while since we posted new animal model data. In collaboration with @BCM_HGSC we are making a new high quality long-read Syrian golden hamster genome. First results are full-length blood transcripts with data here: https://t.co/w4R1yo0mMW

[oconnorlab @dho_lab]

@trentkainalu ’s preprint on automated slow pipetting is now out. A great, simple robot makes it easy to get ultra long @nanopore sequences without much training: https://t.co/4SOweRT7Mn

[oconnorlab @dho_lab]

@GageKMoreno and @KATarinambraun representing!

[Council of Graduate Schools @CGSGradEd]

CGS #GradImpact Shifting Research Priorities to Combat a Pandemic @UWMadison @UWMadGSEd @dho_lab https://t.co/KAdFEE5HEk

[Dave O'Connor @dho]

Our preprint on initial results of rapid turnaround, mobile RT-LAMP testing now available. Much work to do, but pretty encouraging. https://t.co/Ol0y7flwxZ

[oconnorlab @dho_lab]

@Mohr_Lab Behind the bike shed @wnprc. Our approva is for mobile testing outdoors.

[oconnorlab @dho_lab]

My group with @slo_wis , @tcflab , regulatory support from @UWMadison, saliva guidance from @NathanGrubaugh , support from @WARF_News , @wnprc, and @NIH RADx.

[Dave O'Connor @dho]

First day testing van-based, fast-turnaround COVID testing by RT-LAMP. Spit in a tube (h/t @NathanGrubaugh), inactivate for 30 minutes, then RT-LAMP to look for color change. Hoping a version of this could enable twice-weekly testing of teachers to keep schools open.

[Gage Moreno @GageKMoreno]

@KATarinambraun and I have been so fortunate to be in labs that allowed us to shift gears and quickly begin to understand the current pandemic! Excited to see where this all goes! @dho_lab @tcflab

[oconnorlab @dho_lab]

Introducing the Southwest bike trail virus that we identified in common marmosets. Congrats to Anna for getting it into Biorxiv!https://t.co/IyBMkYk1nM

[Gage Moreno @GageKMoreno]

We have updated our WI #SARSCoV2 @nextstrain build to show the 369 genomes that @KATarinambraun and I have sequenced. You can now view it by all of WI, Dane County, or the greater Milwaukee area with higher resolution in the map view ➡️ https://t.co/CYchEnveTc
@dho_lab @tcflab

[Gage Moreno @GageKMoreno]

Our preliminary analysis of the #Milwaukee #SARSCoV2 / #hCoV19 outbreak is on @LabKey at https://t.co/0XlonQnCQP. The Milwaukee epidemic appears to have few introductions and is largely driven by established chains of local transmission.
@KATarinambraun @dho_lab @tcfriedrich

[Gage Moreno @GageKMoreno]

Certain neighborhoods in #Milwaukee have been disproportionately affected by #COVID19 but lacked viral sequencing to understand their outbreak. @KATarinambraun and I were lucky enough to add 93 sequences to the global tree to begin to understand the #MKE outbreak @dho_lab @tcflab