Daniel Freitag

Digital medicine and human genetics: work on translating into patient benefit. Hobby filmmaker. All views my own.

[Declan O'Regan @DrDeclanORegan]

How can we harness AI-image analysis and genetics to accelerate drug discovery? Register now for a talk with me and @FriTagDan from @Bayer on achieving this in @uk_biobank. 🗓️3PM 8th June @imperialcollege. https://t.co/Lgnswpu6vu

[Nature Cardiovascular Research @NatureCVR]

News and Views by @jgustavsmith Olof Gidlöf on the implications of the recent study by @DrDeclanORegan and @FriTagDan teams on the #genetic and #environmental factors influencing #cardiac relaxation and filling https://t.co/eDwPOKQ2cv | @goteborgsuni

👉https://t.co/X4qr0bfx33

[Daniel Freitag @FriTagDan]

Excellent collaboration - glad to see this published!

[Declan O'Regan @DrDeclanORegan]

Diastolic function is involved in many cardiovascular diseases and is a key feature of the ageing heart. In @NatureCVR we use machine learning motion analysis of the heart in @uk_biobank to discover the key drivers of myocardial stiffness. 1/5 🧵
👇https://t.co/ZP30WyiePO

[Declan O'Regan @DrDeclanORegan]

Join our research group @MRC_LMS and @Imperial_Stats on a @TheBHF funded program to predict outcomes from cardiac motion. Great opportunity to develop creative ideas for time-to-event modelling using complex 3D data. https://t.co/VLZDu6lTqu

[Declan O'Regan @DrDeclanORegan]

Great collaboration between our group at @MRC_LMS with @FriTagDan and the team at Bayer. @uk_biobank #datasaveslives.

[Declan O'Regan @DrDeclanORegan]

Last chance to apply for a fully funded PhD with our group studying complex cardiac traits in heart disease. https://t.co/CSNreAnEhC

[Bayer | Pharmaceuticals @BayerPharma]

Many proteins involved in harmful #disease processes cannot be targeted by small #molecule drugs – they are “#undruggable”. Targeting them at the level of #RNA could change this and ultimately offer new treatment options for #patients. Find out more here: https://t.co/txM9GIJ3OJ

[Alexander Hillisch @alexanderhilli7]

...great initiative here at Bayer Pharma R&D. We are building a new team to tap into the field of RNA binding small molecules. Are you an RNA experts, e.g. in biochemistry, biophysics and computational molecular design? We are waiting for your application! https://t.co/3YH6yyzuF3

[Daniel Freitag @FriTagDan]

Exciting new position in my team on the intersection of human genetics, digital technologies and drug development. Work with enthusiastic & brilliant scientists like @floriansohler @creatules @alexanderhilli7 https://t.co/uV8M00lZwp

[Adam Butterworth @aidanbutty]

Great to see our paper on proteome-wide MR studies out today in Nature Genetics, led by @oldz84 @tomrgaunt & @robert_a_scott Some important cautionary tales about testing for colocalisation in an MR setting! https://t.co/AYyBRZ2aO5

[Peter Willeit @PeterWilleit]

Carotid Intima-Media Thickness Progression as Surrogate Marker for Cardiovascular Risk: Meta-Analysis of 119 Clinical Trials Involving 100,667 Patients | Circulation https://t.co/e7vxdwosNJ

[Hans @hans444]

We’re looking for a new colleague in #Boston or #Berlin, a genius data scientist, domain expert in Oncology R&D, leadership star with high learning agility. https://t.co/nYu9hjuadV #teambayer #hiring #scienceforabetterlife

[Patrick Ellinor @patrick_ellinor]

Great work by @broadinstitute CVDI and @QMULWHRI teams on genetics of an ECG trait related to arrhythmias.

Study of PR interval in 300K people identified 200 loci.

[American College of Cardiology @ACCinTouch]

JUST RELEASED: The #ACC20/WCCardio VICTORIA LBCT finding that patients w/ high-risk #HF who take the novel drug vericiguat may have a lower incidence of #CV-related death and HF-related hospitalizations, according to results of the phase 3 trial. https://t.co/m2bn2TZfWW

[Dirk Paul @dirk_paul]

Super-excited to share our latest work on elucidating molecular mechanisms of genetic cross-disease associations: https://t.co/cbw8y11JT8! Comments welcome! @Cambridgecardio @CambridgeBRC

[Declan O'Regan @DrDeclanORegan]

We're recruiting two 3-year post-docs in machine learning - image analysis and outcome prediction. Come and join our growing team in the Computational Cardiac Imaging group @MRC_LMS @BioMedIAICL https://t.co/rDHReE5kcf https://t.co/hJL0ZlP6Di

[Daniel Freitag @FriTagDan]

Looking forward to another exciting day at the @DCRINews think tank on “Leveraging #AI / #ML to transform clinical trial design, planning and execution” with @MarzyehGhassemi @MTRHeart @erichhuang @kshameer

[Svati Shah @SvatiShah]

Our 2020 update for Heart Diseas and Stroke Statistics is out! So great that they began including genetics a few years ago. Honored to work with this group. @American_Heart @JaneFFerguson @virani_md @EmeliaBenjamin @alvaroalone_so

https://t.co/yuEaUsFEBP

[Christian Stegmann @CMStegmann]

Big step towards unraveling the transcriptional complexity of the human heart - it is a privilege to be a member of this collaboration! @broadinstitute @Bayer @BayerUS
👇

[Alexander Hillisch @alexanderhilli7]

...looking forward to developing and making this technology work with a team of highly skilled computational scientists and software engineers at Schödinger and Bayer!