We are very happy to share our latest #singlecell study on identifying the features of primary tyrosine kinase inhibitor (TKI) resistance at the time of chronic myeloid leukemia (#CML) diagnosis/1
#Fluoxetine (#Prozac) changes so many genes in so many brain regions. Mechanism(s) of action are dizzyingly complex, but some promising themes emerge👇. Long-term collab with @meaneylab et al. Large integrative omics study heroically led by @braincrank_nr. @astar_gis#depression
Small but mighty! This is a video of a killer T cell of the immune system destroying a monstrous ovarian cancer cell. I recently captured this data on a spinning disc confocal microscope.
Finally --- the 2nd edition of ISLR is out!!!!🥳🎉🪅🍾
Well, sort of. 🙄It's "published", but due to shortages in the global paper supply, hard copies won't be available for a bit longer 😢😭🤦♀️
You can pre-order a hard copy from Springer/Amazon, & **download the pdf today**! 1/
Are you interested in single cell biology and algorithmics? Join us for the "Single Cell and Spatial Data Analysis" Special Session on July 30 as part of 2021 ISMB/ECCB. We're accepting abstracts for talks/posters till May 31. Check for details here: https://t.co/6MnPPsqHN1
The talk on 4th May 2020 at 9 am Central time will be by Florian Schmidt from @astar_gis. Watch it here -
https://t.co/ZSmVQQ7tu1
Please add to your calendar - https://t.co/Is2d06o46y
The talk will be about Robust clustering of scRNA-seq data using reference component analysis!
Thanks to @bbbranjan and everyone else involved from @shyam_lab at @astar_gis for working with me on this great contribution to improve clustering of single cells, which is now available at BMC Bioinformatics.
Mine and @fschmidt92's collaborative work - scConsensus - is finally out in BMC Bioinformatics! Huge thanks to Wenjie, Jinyu, @AminHonardoost, @braincrank_nr, Joanna and @shyam_lab! Also grateful to the reviewers for helping us improve the manuscript.
https://t.co/XCUNIoxgSG
GIS is starting a new series of monthly scientific talks “Genome: The GIS Speaker Series”. For our 1st session on 7 April, 9am SGT, we invited Dr Sarah A Tishkoff to start this series with her talk on “Genomic Evolution & Adaptation in Africa: Implications for Health & Disease”.
A manuscript by @scherermich, @fschmidt92, @the___olga, @janbaumbach, @itisalist and colleagues reviews state-of-the-art computational methods to better understand the mechanisms of epigenetic regulation, and discusses the ongoing challenges in the field. https://t.co/dgklI3Wd9b
@NatComputSci @scherermich @the___olga @janbaumbach @itisalist Thanks to all collaborators for this very nice review article on computational epigenomics. Go check it out!
The preprint on RCA2, a supervised clustering algorithm for single cell RNA-seq data is available on bioRxiv. Thanks to everyone who contributed form @shyam_lab at @astar_gis especially at @bbbranjan.
https://t.co/lI0aRoUMrx
Are you interested in #SingleCell#epigenomics🤓? Register for our upcoming workshop on Nov 17 and learn about the latest findings and developments in the field from our experts during interesting talks 🤩👉more info & registration: https://t.co/wyBYxZzokn
@fschmidt92 (@astar_gis): RCA2 is a scalable robust unsupervised clustering technique that uses cell-cell correlations to avoid batch effects
https://t.co/aGKqzUexCQ
#HCAasia2020