Top Tweets for #Condensin
Spotlight: Geert Kops previews work from Tran et al. @DumontLab (https://t.co/w6eDCuRo6s), which uses super resolution live imaging to show that #condensin is required for local structural organization and microtubule attachment of #kinetochores. https://t.co/pMLp9hqbMb
Vanna M. Tran, @DumontLab et al. show that mammalian #metaphase #kinetochores undergo large-scale, complex, and elastic deformations under forces of different timescales, magnitudes, and directions. https://t.co/VBjgsI23t1
#CellDivision #Biophysics #Condensin #Microtubules
Takao Ono, Tatsuya Hirano et al. @riken_en show that #condensin II collaborates with #cohesin to establish and maintain #chromosome territories, revealing a cooperative mechanism supporting large-scale #genome organization in #interphase. https://t.co/F37plMYR0c
#CellCycle
‼️ In their latest paper, the @Gerlich_Lab with first author @pauldanielbatty shows that #cohesin can resolve sister chromatids even before cell division.
Cohesin acts by DNA loop extrusion in the G2 phase independently of #condensin or other mitosis-specific activities.
Now published in @embojournal
#chromosomebiology #celldivision #loopextrusion #chromatid #sisterchromatids #mitosis
@viennabiocenter @oeaw
#Cohesin can resolve sister #chromatids already in G2 independent of #condensin - DNA #loopextrusion as generic mechanism for segregating #replicated genomes shared across different #SMC protein complexes
@pauldanielbatty et al @Gerlich_Lab @IMBA_Vienna
https://t.co/vKDhwmZtXb
#Cohesin can resolve sister #chromatids already in G2 independent of #condensin - DNA #loopextrusion as generic mechanism for segregating #replicated genomes shared across different #SMC protein complexes
@pauldanielbatty et al @Gerlich_Lab @IMBA_Vienna
https://t.co/vKDhwmZtXb
Scientists clarify role of #condensin in #mitosis. #cellcycle @RIKEN_CPR https://t.co/nk78pyyayX https://t.co/PHy8Tgw38L
Our research was featured on the cover of the current issue of @CellReports. The picture is an artistic interpretation of how mitotic #chromosomes are built by #condensin molecules. Made in @Blender using the #molecularnodes package developed by @bradyajohnston.
Our paper on #3dgenome structure at #mitosis is finally out in cell reports. We develop a theory that shows; how many #condensin proteins come together to form the mitotic #chromosome by #loopextrusion. 🧵(1/8)
Structural changes in chromosomes driven by multiple condensin motors during mitosis https://t.co/PZE3hIEgfg
How does #condensin #SMC complex extrude DNA loops?
It generates DNA translocations steps by pinching a short negatively #supercoiled loop during each round of ATP hydrolysis
Belén Martínez-García @SilviaDysonn @Joanna_SeMa Joaquim Roca et al @IBMB_CSIC
https://t.co/kCT1mIiOzg
"Taken as a whole, this work has the potential to reveal a molecular basis for the cell cycle regulation of condensin I in vertebrate cells and as such to significantly improve our understanding of the integrated functioning #condensin I."
Rev#1
"Cell cycle-specific loading of condensin I is regulated by the N-terminal tail of its kleisin subunit"
#RefereedPreprint #CellBiology
Shoji Tane, Tatsuya Hirano et al
https://t.co/2ioDKvTOBN
I followed @bradyajohnston's #blender tutorial to render the #condensin CAP-H CAP-G complex. I'm very very impressed with the tutorial. I haven't done any 3d render in blender before. Maya was long time back too, so it's nice to make 3d art again.
Kinoshita et al. address the role of #condensin I in #chromosome assembly and identify two classes of mutations that cause hyper- and hypocompaction phenotypes in #Xenopus egg extracts. https://t.co/GQp7TdtVrD
Part of our #Chromatin Biology collection: https://t.co/9QRGXDaq5S
Proud to have brought together labs around the @viennabiocenter, and across the Atlantic, on this collaborative effort to understand how DNA looping and chromatin volume compaction cooperate to form mitotic chromosomes! #chromatin #mitosis #condensin #histone #phaseseparation
6/6
Read our latest review on Making Mitotic #Chromosomes in a Test Tube by Keishi Shintomi @RIKEN_BDR
https://t.co/eSdwIbIp55
#ChromosomeDynamics #Xenopus #Condensin
Hello #AcademicTwitter and #3dgenome I have a new pre-print out on how #loopextrusion by multiple #condensin motors can explain #mitotic #chromosome structure. So let’s get to it, (a 🧵1/12)
New mechanistic insights into how #DNA loops are created by molecular motor #condensin in last week's @ScienceMagazine article by @HaeringLab + al https://t.co/xI8SGVluwT. Check out Movie S9 - mesmerizing: #Topology in #Biology
Great collaboration, awesome results @science: how the protein #condensin succeeds in packaging loosely arranged strands of #DNA into compact individual #chromosomes during cell division. Congrats @embl & JMUW Biocentre group of Christian Häring! ➡️https://t.co/XLSwovr1Hp
Trying my hand at stop-motion to understand #condensin and #SMC loop extrusion! First movie: the hold and feed model from @HaeringLab A really nice model integrating structural, biochemical and single molecule data. The biggest challenge was threading the DNA correctly!
Very cool new work about the surprising role of #condensin II for #SAC (#spindleassemblycheckpoint) activation in #drosophila male #meiosis from @CHR_lab.
https://t.co/bsnj1saAxL
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