Top Tweets for #DnaRepair
New!👣
Targeting the #DNArepair chromatin-modifier protein SMYD3 as a novel epigenetics-based therapy for #gastriccancer
Look here👇
https://t.co/o71dhS8oU4
#DNAdamageresponse
#HomologousRecombination
#PARPinhibitors
Check out the latest @NatureComms paper co-authored by the Sung & Olsen lab: Mapping 6,888 RAD51D variants sheds light on DNA repair and helps interpret cancer-linked genetic changes. https://t.co/47AwcTXbIj #Kids #Cancer #Hope #CancerResearch #Genetics #DNARepair #RAD51D
Can hyperactive #DNArepair be targeted in #Neuroendocrine #CervicalCarcinoma?
#Multiomics reveals HRR activation and a CAF–IL6–E2F1–BLM axis that limits #PARP inhibitor sensitivity, supporting dual PARP–BLM inhibition. @TJU_China
#STTT #OpenAccess: https://t.co/bUzBkO74Ti
Why smFRET?
Bulk methods average billions of molecules and blur small changes.
smFRET measures each one, so a single-oxygen shift shows up.
We put this on the benchtop with EI-FLEX Pro. Talk to us: https://t.co/z16sxeljpi
5/5 #smFRET #DNArepair
“DDX3X regulates DNA repair pathway choice at double-strand breaks via RNA-DNA hybrid formation”
This work highlights a new mechanism controlling #DNARepair and tumor cell sensitivity to #chemotherapy ⤵️
https://t.co/jjRBP8A6nl
🧬 A study in Nature sheds new light on #DNArepair in early human embryos, with implications for future gene correction.
See more ► https://t.co/XPAx5GD0IF 📲
#IOCB #IOCBPrague @Columbia
RESEARCH PAPER: MRE11 suppresses germline mutagenesis at meiotic double-strand breaks in mice
By Lukaszewicz et al., Scott Keeney, and Maria Jasin
➡️ https://t.co/mdKKPJW76V
@umichmedicine @MSKCancerCenter
#DNArepair #meiosis #mutagenesis #genome #evolution
💡Calling for Submission💡
📖Molecular Mechanisms of DNA Replication and Repair
🧑🔬Guest Editor: Dr. Sneha Saxena
⏰Submission Deadline: 31 January 2027
🔗Find out more: https://t.co/XwfrY5u0kp
#callforpapers #mdpiijms #openaccess #DNA #DNArepair
Excited to share our paper, now out in @JCellBiol!🎉
Co-led with George Galea at @embl , we uncover a new layer of spatiotemporal regulation of the #DNADamageResponse between the Golgi and the #Nucleus, revealing an active role of the #Golgi in #DNArepair.
https://t.co/asgxfU0y54
RecN emerges as a tunable switch coordinating DNA repair choice and stress-resilience programs #DNARepair #StressResponse #GenomeEngineering
Details: https://t.co/NTBmbTcbLp
George Galea, Karolina Kuodyte, Rainer Pepperkok et al @embl reveal that RAD51C is anchored at the Golgi by Giantin until DNA damage triggers ATM-dependent release & nuclear import, establishing the Golgi as a spatiotemporal regulator of nuclear #DNArepair https://t.co/m8O2RNNyGu
RecN emerges as a tunable switch coordinating DNA repair choice and stress-resilience programs #DNARepair #StressResponse #GenomeEngineering
Details: https://t.co/NTBmbTcbLp
RESEARCH PAPER: Coupling of translesion synthesis with the replisome stabilized at stalled replication forks by ATR
By Yoon et al. and Satya Prakash
➡️ https://t.co/ALFxCGGzE0
@utmbhealth
#DNAreplication #DNArepair #genomestability #translesionsynthesis
Molecular Oncology in Clinics
DNA repair biology is no longer just basic science!
#MolecularOncology #PrecisionOncology #DNARepair #CancerGenomics
Drug Candidate Shows Early Promise for Treating Alzheimer’s Damage
Results from an animal study show KCL-286, a retinoic acid receptor-beta agonist, could be an effective new treatment for #Alzheimersdisease
@KingsCollegeLon
#DNArepair #mouse
https://t.co/LL9EfPyDGQ
If you study #glioblastoma, this paper is essential.
CUDC‑907, a dual PI3K/HDAC inhibitor, curbs growth & invasion, promotes #apoptosis, and synergizes with temozolomide by blocking #DNArepair & #CellCycle pathways, with minimal toxicity. @CQU1929
Read: https://t.co/4jHmzhTqM7
Honored to present both a short talk and a poster at GRC 2026: Mutagenesis in Waterville Valley, NH. I discussed our latest work on BRCA1-associated tandem duplications. Thanks to the organizers, postdoc mentor Prof Ralph Scully & lab. #GRC #Mutagenesis #DNARepair #CancerResearch
Alba Muniesa-Vargas, Hannes Lans et al. (Erasmus MC) use live-cell imaging to uncover how XPG activity is dynamically controlled during nucleotide excision repair. https://t.co/2YYWZStFu2
#DNAbiology #Genetics #DNArepair
Excited to share our paper, now online in @NatureComms ! We show that break-induced replication and hyper-resection form long, mutable ssDNA during meiosis, creating mutation clusters with implications for evolution and disease.
https://t.co/LQwERxMG3X
#meiosis #DNARepair
PERSPECTIVE: Structure, function, regulation, evolution, and therapeutic implications of PARP14
By Kar et al., and Ivan Ahel
➡️ https://t.co/XAIZ608yaU
@IvanAhelLab @UniofOxford
#PARP #ADPribosylation #immunity #DNArepair
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