Top Tweets for #Losmapimod
How did #losmapimod fare against placebo in the phase 3 REACH clinical trial including 260 adults with #FSHD? Read on to discover the results, presented at @MDAorg: https://t.co/CHQn8KaHrJ
@KUMedCenter
This @KUMedCenter researcher investigated #losmapimod vs. placebo in #FSHD, a rare, progressive genetic muscle disorder. The results, which may be surprising, were presented at @MDAorg: https://t.co/CHQn8KaHrJ
🇺🇸 #FSHD
🤚A note to our families from CEO Mark Stone
@FulcrumTx : The results showed no difference between placebo and active ingredient groups. Therefore, Fulcrum is suspending future #Losmapimod development.
https://t.co/7u7G0M4EZX
🇪🇺🇳🇱
👉An open-label pilot study of #losmapimod to evaluate the safety, tolerability & changes in biomarker and clinical outcome assessments in participants with #FSHD
💡Losmapimod was well tolerated and may be a promising new treatment
📰https://t.co/ix9dI4dr7G
@FSHD_Leiden
🇺🇸🇨🇦 - 🇪🇺🇪🇸🇫🇷🇳🇱🇸🇪
👉Safety and efficacy of #losmapimod in #FSHD: a randomised, double-blind, placebo-controlled phase 2b trial
💡Although it did not change DUX4-driven gene expression. Potential improvements in muscle & patient-reported global impression of change
@pacmanyourass That's an interesting thought, Steve. I cannot comment on the dose but hopefully, ongoing research will lead to better understanding and more effective treatments for FSHD. #Losmapimod #FSHD
@pacmanyourass Results of ReDUX4 phase IIb trial for #FSHD treatment with Losmapimod were mixed. While disappointing, let's remain hopeful for more breakthroughs in the field. #Losmapimod #RareDiseases #ClinicalTrial #Research
#Losmapimod, a potential oral treatment for #FSHD, missed its main goal in a recent Phase 2 clinical trial, but its developer, Fulcrum Therapeutics, sees this as a constructive failure. Read more: https://t.co/oMMdkBahjS
#musculardystrophy #livingwithMD #MD #treatingMD
• This was the most read article this week on our #MuscularDystrophyNews website! Have you read it? •
In an interview, #Fulcrum's CEO and CMO talk about muscle gains seen in #losmapimod ReDUX4 trial, and plans to advance potential #FSHD therapy. Read:
https://t.co/oMMdkBahjS
#Fulcrum provided an update on ReDUX4-the Phase2b clinical trial testing the safety & efficacy of #Losmapimod to treat #FSHD. #AMRA’s advanced #MRI analysis can potentially help detect changes prior to individuals experiencing muscle-related difficulties: https://t.co/dp9V5Y798p
#Losmapimod Improves Function and Slows Progression of Facioscapulohumeral Muscular Dystropy #diseaseprogression #musculardystrophy #neurology #PracticalNeurology https://t.co/Itf3rR2mex
:: This was the most read article of this week in our MD News website!::
The FDA has granted fast track designation to losmapimod, a potential treatment for facioscapulohumeral muscular dystrophy (FSHD).
Read here: https://t.co/pf3anviA56
#musculardystrophy #FSHD #losmapimod
Diego Cadavid, MD of Fulcrum Therapeutics summarizes abstracts presented at the American Academy of Neurology Annual Meeting focused on facioscapulohumeral muscular dystrophy #FSHD #losmapimod @FulcrumTx @FSHDSociety Fulcrum Therapeutics FSHD Society
https://t.co/9qekDa1ruE
Diego Cadavid, MD of Fulcrum Therapeutics summarizes abstracts presented at the American Academy of Neurology Annual Meeting focused on facioscapulohumeral muscular dystrophy #FSHD #losmapimod @FulcrumTx @FSHDSociety Fulcrum Therapeutics FSHD Society
https://t.co/9qekDa1ruE
#Internacional | #Losmapimod de @FulcrumTx no ha funcionado mejor que el placebo #en #pacientes con distrofia muscular facioescapulohumeral https://t.co/nHMlooZfns
#Internacional | Revés para @FulcrumTx: #Losmapimod no funciona mejor que el placebo en #pacientes con distrofia muscular facioescapulohumeral https://t.co/NjwOaIo9D3
A quick look at the $FULC setback, MRI and functional data next year will really need to impress to keep #losmapimod off the scrapheap: https://t.co/9Mg961tF3y #FSHD
Diego Cadavid, MD of Fulcrum Therapeutics summarizes abstracts presented at the American Academy of Neurology Annual Meeting focused on facioscapulohumeral muscular dystrophy #FSHD #losmapimod @FulcrumTx @FSHDSociety Fulcrum Therapeutics FSHD Society
https://t.co/9qekDa1ruE
@onelifemax @VirusPathways @pedrobeltrao @dlswaney @VignuzziLab @KroganLab @DoctorBou @_b_meyer @virusninja @jeanklim @verorezelj @BenjaminNilsson @kevansf @danishm20 @grosse_lab @CellCellPress @barabasi @Baric_Lab @davidasinclair @dandavis101 @GladstoneInst @foundmyfitness @JuliaB_fitness @mdpatrick @RMedzhitov @VirusesImmunity @Dmozaffarian Intriguingly, @gilroylab_ucl et al recently showed that blocking elevated #p38MAPK (in humans, using #Losmapimod) restores efferocytosis and inflammatory resolution in the elderly. #AntiAging #COVID19 https://t.co/M2Y7s5EC1Q
#Losmapimod, an investigational small molecule drug to lower expression of a transcription factor thought to cause facioscapulohumeral #MuscularDystrophy, had favorable tolerability & safety. Read on for more info. @AANMember #AANscience https://t.co/BsC0YzUfeY
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