Top Tweets for #NuclearPore
#Excessive activity of the protein VCP disrupts #NuclearPore integrity, leading to toxic protein mislocalization and neuronal damage in #NeurodegenerativeDiseases such as ALS and certain dementias. @BCMHouston @neurocellpress https://t.co/GCTnRLVxGT https://t.co/qwKdvDVtsn
High-resolution cryo-EM images reveal how ##Hiv-1 viral cores adapt to pass through the #NuclearPore, highlighting new cellular mechanisms that could inform future antiviral strategies. @DiamondLightSou @NatureMicrobiol https://t.co/ovK52bMMpf https://t.co/zgdKlBKKX6
💫NEW: Stankunas and Köhler define how the nucleoplasmic portion of the #NuclearPoreComplex (NPC), the basket, docks onto the #NPC core.
@MaxPerutzLabs
#nuclearpore #nuclearbasket #Nup60 #Mlp1
https://t.co/003EVwxFov
Giant cargo opening a large enough hole through the nuclear envelope by breaking the scaffold of the #nuclearpore
In a great collaboration with @HummerLab and the Kräusslich lab, @jpkreysing, @MaziarHeidari1, @VojtechZila and others tackle what happens when HIV capsid goes through an NPC. Instead of the NPC cracking the capsid, the capsid appears to crack the NPC (@MPIbp @CiidHeidelberg).
Cool! #TPR #NuclearPore #NPC #NuclearBasket
TPR is required for cytoplasmic chromatin fragment formation during senescence | bioRxiv https://t.co/5ww2isfAUV
A study in @JCellBiol of how the critical #nucleus & #mitochondrion interact, performed in the protozoan parasite #Toxoplasma, reveals a contact mediated by abundant & ubiquitous complexes in their membranes #TOM #NuclearPore https://t.co/m9HsY8WjYa
@sheinerlab @UofGSii @MGissot
A study of how the critical #nucleus and #mitochondrion interact, performed in the protozoan parasite #Toxoplasma, reveals a contact mediated by abundant & ubiquitous complexes in their membranes. #TOM #NuclearPore https://t.co/Cv16EZeMvo
@sheinerlab @UofGSii @MGissot
How can genetic perturbation of a central scaffolding component of the #nuclearpore result in a tissue specific defect? Work by @Reiya_Tan1guch1 and others in collaboration with @DoyeValerie makes this more conceivable (@MPIbp @IJMonod):
https://t.co/PpM1Tw0Rsc
Making an Entrance: #Cell nucleus–cytoplasm #nuclearpore complex of hundreds of proteins is assembled & organised via 2 different mechanisms Image & research by @ShotaroOtsuka et al @EllenbergLab @embl in @Nature. On https://t.co/tRbfbAdsfY with article links & searchable archive
Congratulations to Janka Zsok and Elisa Dultz for their paper on the #nuclearpore basket in collaboration with @LucienWeissLab. The first preprint from the Dultz group!
"doRITE" and have a look at tracks of single NPCs.
https://t.co/U14i91BZRX
✳️´Puzzling out nuclear pore complex assembly´ in the new Review by 🖊️A. Penzo @PenzoArianna & B. Palancade @PalancadeLab.
Understanding NPCs to learn about the biogenesis of multiprotein complexes
➡️ https://t.co/zN801nqYpx
#NuclearEnvelope #NuclearPore
Beautiful work by @HiralABShah and the Dey lab @Dey_Gautam. And those #nuclearpore arrays are really pretty! Looking forward to more on those! https://t.co/uirXEnUI0N
Scientists at IMB, @uni_mainz & @MPIbp showed how #IDPs in the centre of the #NuclearPore form a spaghetti-like mobile barrier that allows important cellular factors to pass but blocks viruses & molecules that can cause disease. #condensate #biophysics
📰https://t.co/CNkzezGpUZ
Please retweet- Postdoc positions are available @YildirimlabDuke (https://t.co/QatXfzb0W6…). If you are interested in research involving lncRNA-mediated epigenetic mechanisms and/or spatial organization of gene expression, come join us! #Xinactivation #epigenetics #nuclearpore
Postdoc positions are available @YildirimlabDuke (https://t.co/PJ2A0fnPaJ). If you are interested in research involving lncRNA-mediated epigenetic mechanisms and/or spatial organization of gene expression, come join us! #Xinactivation #epigenetics #nuclearpore #hematopoiesis
Peroxisomal import uses a selective phase composed of YG domains! #nuclearpore
Excited to share our recent work revealing the nature of peroxisomal protein import channel. Thanks to @HHMINEWS @DamonRunyon for generous funding support. https://t.co/rPxQEHO8e5
An excellent work from Tom Rapoport's group：
https://t.co/5IfYxMnxBi
suggesting a selective YG repeat phase/#biocondensates similar to that in #nuclearpore. Indeed complementary to our findings (@SimoneReber) with engineered YG repeats reported: https://t.co/uImlsqlm9Z
Public lecture by the first #WLA laureate of life sciences, Dirk Görlich:
https://t.co/vOTF89payT
He presented the whole story of selective phase model/ FG phase in #nuclearpore and #biocondensates
, work of @BroderSchmidt @eLife, and @NatureComms @embojournal @mpi_nat
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