Top Tweets for #PitfallAlert
🚨#IHCPath pitfall -> Diffuse nuclear INSM1 expression in sinonasal lymphoepithelial carcinoma!
Luckily, lack of neuroendocrine morphology, synapto/chromo -ve & EBV-ISH+ sorted this case out.
Read more @IJSPjournal: https://t.co/rSTW8F7081
#HeadAndNeckPath #ENTPath #PathTwitter

Atrophic skeletal muscle in a case of fibromatosis can look like multinucleate giant cells


🚨Pitfalls in #IHCPath
Cathepsin K (clone EPR19992) is diffusely +ve in oncocytoma (strong) and chromophobe RCC (weaker), as well as in the distal renal tubules.
Read more about it here @ ISJP 👉🏼 https://t.co/UGK6C74Hly
Lesson learned: know your clone!
#PathTwitter #GUPath

Different faces of esophageal submucosal glands and ducts in post neoadjuvant setting👇. They can look highly atypical, mimicking malignancy especially on high power. Stay low power.
@CooperPathology
#GIpath #Pathtwitter #Pathresidents #Medtwitter

https://t.co/DuTHG3b6Wo

Urethral papillary tumors are often presumed to be urothelial neoplasms. However, performing HPV-ISH can help recognition of a condyloma and prevent a misdiagnosis as malignant (see images). Similarly, basaloid squamous carcinoma with papillary architecture may be confused with high-grade papillary urothelial carcinoma. In such cases, HPV high-risk ISH can be useful in confirming the correct diagnosis. #GUpath

Pitfall alert. This is a calcifying synovial sarcoma (associated with better prognosis than non-calcified). Calcifications and a mast cell are indicated in various images. PRAME is widely expressed in sarcomas, including synovial sarcoma. #UMiamiPath
Reference; 27993576.

Incidental finding in a duodenal biopsy!
Spindle cell lesion??
Nah! Crushed Brunner glands 👍
I have seen these worked up due to concerns of neuromatous lesions.
See description of this phenomenon by @RaulSGonzalezMD
“Brunner glad paste”
https://t.co/ZUdFbiTF4J
#GIpath

Great discussion with incoming PGY1 @piperuso2 and PGY2 @fcamachocord about a PET-avid lung (arrow) & pleural nodules in a px with h/o melanoma. #pitfallalert #notcancer

#pitfallalert
An excellent case by @alegru18 with important lessons
1.Don’t let the CK’s lead you astray
2.PCALCL’s can also show aberrant CK expression (all of them) similar to their nodal counterparts.
#dermpath #hemepath
An 81-year-old male presented to his dermatologist with an ulcerated pink nodule on the right lower cheek that arose 3 months prior and had rapidly grown to 3 cm.

Antibody clone-dependent TTF-1 positivity described in a case of Merkel cell carcinoma 😱
I thought of @smlungpathguy when I read this 🤣😁🤣
#dermpath #IHCpath #pathology

Residual Brown fat is common in cervical lymph nodes and should not be mistaken for neoplasms #pitfallalert.. Nice one sir @tumashankar
16yF PCT. Neck nodes. Anush👍
@archibhat3 @VijayPath1p @lovelygeorge10 @Swathiprabhu5 @DrVasudevPrabhu @vi_monappa @padmapathology1 @glinglerimek @Divya_Madhala @DrGeeONE @kriyer68 @Vik_deshpandeMD @Histopatolomon @TristanRutland7 @pepeheffernan #thyroid #PathTwitter

A pitfall alert and useful tips from the one and only @sza_jhcyto
#pitfallalert #tips #residents #pathologists #cytopath #ENTPath
A fairly common issue in Salivary Gland FNAs of "Pleomorphic Adenoma" - the focal "Pseudo Adenoid Cystic" appearance. Unlike Adenoid Cystic CA, these globules are significantly smaller, often numerous/multiple, with the globules showing a vague "fibrillary" composition.

Dispersed PARAGANGLIA in lymph node dissection for #kidneycancer
Small nests of cells with bland nuclei & variegated amphophilic/basophilic (purple-ish) to clear cytoplasm
Often seen in proximity to nerves
#PitfallAlert #gupath
CAUTION: do not confuse w/metastatic carcinoma

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