Top Tweets for #Prmt1
Article✍️The protein #arginine #methyltransferase #PRMT1 ameliorates #cerebral #ischemia–#reperfusion #injury by suppressing #RIPK1-mediated #necroptosis and #apoptosis. From Dr. Liu @ShandongUniversity;
https://t.co/vLr8F1cDeD.
✅If #PRMT1 has a direct action on NF-κB b by #suppressing it under #physiological #conditions, how could we define the switch or #therapeutic #target in pathological conditions? Is it PRMT1 #overexpression or #suppression of NF-κB downstream signaling?🫰🫰🐁🐁
✅Proinflammatory mediators such as #TNF-α, #IL-1, and #ROS promote the activation of NF-κB to trigger inflammatory response signaling. Could inhibiting the synthesis of these mediators generate an anti-inflammatory response? 🙏🫰🐁🔬
@AdvPhysiolEduc @ATHjournal @atvbahajournals @CircRes @CircHF @FrontPhysiol @HaoYin20 @WashUDeptMed @WashUCardiology @gkolost @GizemEfePhD @Ahmed43101178 @drshafikuchay @IEEEembs @J_Cell_Sci @LuisSobrevia2 @CMPLPUCCHILE @FacMedicinaUC @TheIUPS @SocFisiolChile @ALACFdifusion @CHESTPulmCardio @LungCancerEu @RCMjournal @TrackYourHeart @NatRevCardiol @JCVPOnline @CNIC_CARDIO @CTRC_UofSCSOM @RockUPress @NatureCVR 👇👇🧵🧵
How does PRMT1 affect #endothelial cells in the context of #COPD? 🤔
Researchers show that by suppressing NF-κB activation and preventing inflammatory shifts, PRMT1 protects against endothelial dysfunction, inflammation, and senescence in COPD.
https://t.co/HWX8AValgs
Could reduced levels of #PRMT1 and #PECAM1 be #biomarkers for #early #detection and prevent the development and progression of COPD? 🫰🧬🐁
Could treatment with BAY-11-7082 be the #drug of choice for COPD in the future by inhibiting the NF-κB #pathway, thereby preventing the development of #senescence and #endothelial #dysfunction?🫰🔬🧬
Could BAY-11-7082 be effective in preventing endothelial dysfunction in non-pulmonary #vessels?🐁🔬🐁🐁🧬
@atvbahajournals @gkolost @LungCancerEu @HyperAHA @IEEEembs
@PVRI @The_MCSociety @CirVascularAND @CircRes @ajpheartcirc @HaoYin20 @CMPLPUCCHILE @LuisSobrevia2 @JCVPOnline @CTRC_UofSCSOM @CNIC_CARDIO @WashUDeptMed @WashUCardiology @SocFisiolChile @IFPA_Official @ResearchGermany @IJMS_MDPI @ESC_Journals @NatRevCardiol @hopkinsheart @escardio @HypertensionAus @SAC_54 @isth 👇🧵👇
How does PRMT1 affect #endothelial cells in the context of #COPD? 🤔
Researchers show that by suppressing NF-κB activation and preventing inflammatory shifts, PRMT1 protects against endothelial dysfunction, inflammation, and senescence in COPD.
https://t.co/HWX8AValgs
Online now: PRMT1 promotes pancreatic cancer development and resistance to chemotherapy https://t.co/9qPzlc8uqC
Check out our recent publication on PRMT1 where we discuss the structure, biochemical features, specificity, regulation, and cellular roles of PRMT1. @Davie7Jim
Access the paper through the link https://t.co/FrQbfprQwR
#Newpublication #Epigenetics #Research #PRMT1
Join the 2/15, FREE, online @FASEBorg discussion on #Protein #Arginine #Methylation in Physiology and Disease. https://t.co/kjQZdZbQEl
Keynote: Mark T. Bedford, PhD @MDAndersonNews
#CARM1 #PRMT5 #PRMT1 #proteins #lysine #PRMT
Attention #GradStudents and #PostDocs studying protein arginine methylation! Join organizers Wei Xu @McArdleLab and @PeterLewisLab for a FREE virtual conference on Wed. February 15 to explore new mechanisms in this exciting discipline. Register: https://t.co/0dUG5lS4y8
Excited to get my last PhD work published @IJMS_MDPI, great team work! Huge thanks to the whole @LeRomancerLab!
#breastcancer #PRMT1 #genesilencing
https://t.co/1cIfBpr3Sx
Article✍️#Prmt1 upregulated by #Hdc deficiency aggravates acute #myocardial infarction via #NETosis. Unveil the role of HDC in NETosis by histamine–H1R–#ATP–SWI/SNF–PRMT1–#ROS signaling & provide new biomarkers and targets for in #cardiovascular disease.
https://t.co/MiQ2M7cbad.
Could #PRMT1 be a potential target for #PancreaticCancer?
@codex_dna #BioXp gene synthesis technology used in this study to ID epigenetic vulnerabilities in the hard-to-treat #cancer.
📘https://t.co/R66eqxGefZ
#Epigenetics #NaturePaper #GeneSynthesis
Uta-Maria Bauer and coworkers @Uni_MR find #PRMT1-mediated #arginine #methylation of p14-ARF promoting its tumor suppressor function
https://t.co/s0LZwzXLyY
#JimDavie @umanitoba is detecting histone H3R2me2s (symmetric) and H4R3me2a (asymmetric) in the transcription active chicken polychromatic erythrocytes fraction and mapping them to the genome! @asilomarchroma #arginine_methylation #PRMT1
Reduced arginine methylation of key proteins may contribute to neurotoxicity in #C9orf72 #ALS. But how does this happen? A new study from the #HattersLab @unimelb suggests one possibility https://t.co/ohzhr3Eusa via @RossollLab #PRMT1 #PRMT5 #StressGranules
Interesting take on DPR toxicity: GR and PR polymers jam ribosomes during translation and inhibit arginine methylation, causing widespread downstream effects across various biological processes
Congrats to Nick Hartel on getting his work on methyl-proteomics accepted at Molecular and Cellular Proteomics! Great work, Nick! #arginine #PRMT1 #neutral_loss #methyl_switching @molcellprot https://t.co/JysOehNIh3
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