Top Tweets for #Stemness
This @CommsBio study identifies PDLIM4 as a potential #biomarker and therapeutic target for overcoming chemoresistance in advanced #ColorectalCancer. https://t.co/IEI5RRLceB
PDLIM4 promotes acquired resistance to 5-FU by enhancing the #stemness, anti-apoptotic capacity, and drug efflux of colorectal cancer stem cells.
Scientists with Drs. Doron Betel and Andrea Schietinger show in @CellCellPress that LEF1 is essential for T cell #stemness. https://t.co/IrelAZ46XD
Using preclinical models of autoimmune type 1 #diabetes and chronic infection, they discover that a small subset of TCF1hi T cells express the transcription factor LEF1. π§¬
π₯ #AgingShort:
Abstract #video about this #review recently #published in Volume 18, titled "The love and hate relationship between cellular senescence and stemness.β @uoaofficial
π https://t.co/dVoegg84Qb
#aging #PaperSpotlight #senescence #stemness #cancer #oa #publishing
Researchers including Dr. Yu-Fei He propose a framework in which #hepatocytes dedifferentiate into bipotent progenitors as a pre-malignant state, undergo malignant transformation, and a subset acquires #stemness through DNMT-mediated reprogramming.
π‘ https://t.co/mw8ntri7Xu
Diverse stromal and tissue-specific parenchymal cell populations actively shape metabolic niches through context-dependent interactions, thereby reinforcing CSC #stemness and adaptive potential.
https://t.co/SBHmGyHDpI
This study reveals that targeting Wnt/Ξ²-catenin activation in combination with temozolomide synergistically inhibits #Glioblastoma (GBM) growth, invasion, and #Stemness, offering a promising therapeutic strategy for treating GBM. @VCU
#OpenAccess: https://t.co/hQOsVbFfpC
Scientists investigated the mechanism by which STAT3 signaling mediates drug resistance.
They reported in @BrJCancer that STAT3 regulates the expression of #stemness markers, which contribute to drug resistance. π§«
π https://t.co/G9FRCDeoFG
π΅οΈ Investigators revealed for the first time that 25-Hydroxyvitamin D exerts antitumor effects by promoting exon 13 skipping of KDM6A, which suppresses the proliferation and #stemness of #BreastCancer cells and lacks H3K27 demethylase activity.
@oncogenejournal | https://t.co/8obIStEvNj
Scientists demonstrate that GDF15 acts as a tumor promoter in colorectal cancer by driving EMT, facilitating proliferation and metastasis, and enhancing cancer #stemness.
π Read the full study: https://t.co/iVm26J943w
Comparison of stem cell characteristics between perichondral-derived stem cells and periosteal stem cells in postnatal rats
https://t.co/rtdR1BI7yC
#Perichondral-derived stem cells (PCSCs) #Periosteal stem cells (PSCs) #Stemness characteristics
Dr. Shih-Chieh Hung and colleagues reveal 5hmC levels positively regulate MSC self-renewal and osteoblast differentiation. π¦΄
Check out the paper in @NatureComms to learn more about the role of DNA hydroxymethylation in #stemness.
π https://t.co/qg4drT9MwN
Scientists discovered that #mesenchymal stem cells in 3D #spheroids exhibit reduced proliferation, enhanced #stemness, and distinct metabolic adaptations, including increased glycolysis and altered nutrient metabolism. π§«
βοΈ Dig into the results: https://t.co/so3ARJruHw
Glad to share our latest @sigtrans_sttt review on #cancer #stemness and #epigenetic. Kudos to @ClaudiaGalassi9 for taking the lead, not possible w/o critical input from Ilio Vitale #offttwitter and @ManelEsteller @CarrerasIJC @FoxChaseCancer Free at https://t.co/F461qTWV44
Reporting our Signal Transduction and Targeted Therapy @SpringerNature article explaining how #epigenetic shifts are involved in #cancer cell plasticity and #stemness, led by Lorenzo Galluzzi @FoxChaseCancer @deadoc80 and @IlioVitale
https://t.co/v0DOA5XR9z
Glad to contribute to discovery of #chromatin regulation and #stemness #pluripotency mediated by NF-ΞΊB signaling in @biorxivpreprint led by brilliant Luis de Palma, Lluis Espinosa and Anna Bigas @BigSpinLab @HMar_research
https://t.co/mA1xi9e4Gc
Comparison of stem cell characteristics between perichondral-derived stem cells and periosteal stem cells in postnatal rats
https://t.co/rtdR1BI7yC
#Perichondral-derived stem cells (PCSCs) #Periosteal stem cells (PSCs) #Stemness characteristics
Supplementation with A. muciniphila, butyrate or a butyrate producing high-fiber diet significantly reverses both psychological stress-induced #tumor growth and #stemness.
By Bai Cui, Fei Peng, et al. from @DMU_China
https://t.co/Wk765A9ggT
Online Now! @SickKidsNews celebrates 20 years of #stemness, exploring how early gene signatures led to the discovery of stem cell #hypertranscription. Read more at Stem Cell Reports: https://t.co/ZMVklrrpdY
@ISSCR @CellPressNews @GairdnerAwards
π Investigators explored cancer stem cells, a critical contributor to cancer #metastasis and therapy resistance, and detected an upregulation of #stemness in palbociclib-resistant ER-positive #BreastCancer cells.
π https://t.co/90NuP3uwbF
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