Top Tweets for #TcellEngagers
Jazz Pharmaceuticals (JAZZ) builds $4bn oncology option through AbCellera partnership https://t.co/fqKBIHOwCA $ABCL $JAZZ #AbCellera #JazzPharmaceuticals #OncologyLicensing #TCellEngagers #GastrointestinalCancer #Nasdaq #BiotechDeals #BiotechStocks
Interested in designing #TCellEngagers? 🤔
This #review examines strategies for their design that maximize cancer-killing activity while minimizing toxicity.
Read it in @Protein_Cell: https://t.co/seIfYSunmT
🚨 Bristol Myers Squibb & Janux partner to develop tumor-activated T cell engagers for solid tumors - aiming to reduce toxicity and unlock TCEs beyond blood cancers.
@bmsnews @januxrx
🔗 https://t.co/lND99a5qpZ
#Biotech #ImmunoOncology #TCellEngagers #OncoDaily
#TcellEngagers (#TCEs) are engineered to redirect the body’s #Tcells toward disease. Their versatility, expanding target range, and growing clinical impact are redefining immune-based therapy. @CullinanTx researchers describe why they’re rising so quickly. https://t.co/7nldAT1gHX
Hearing from @thenasheffect at the @OUHealth-hosted #BestOfASCO In Oklahoma City! Some great topics! My favorite is on the #TcellEngagers! @ASCO #ASCO25
my favorites #TCellEngagers companies
$JANX $1.4Bn MCAP Phase 1b JANX007 Prostate Cancer:$+1bn partnership with @Merck
$ABP $20M MCAP: BP-102/CT-P72 solid tumors $1.75Bn partnership with @Celltrioninc
stock performance
$JANX -56% YTD
$ABP -98% YTD
$XBI $IXHL
$ABP is cheapest the company developing #TCellEngagers drugs. The space is getting exciting again.
$ABBV is heavily invested in #TCellEngagers space through doing many deals in 2024/2025
$IXHL $BTA $MRM $NCNA $LPSN $SGBX $IBG $TPIC $NLSP $OSCR $GNS
Top of the Edge Data and Top Experts at the ETOP Workshop on T Cell Engagers - Martin Reck
@etop_ibcsg
https://t.co/0BelBqXUs5
#OncoDaily #Oncology #Cancer #Health #Medicine #MedTwitter #MedEd #MedOnc #MedNews #ETOPWorkshop #TCellEngagers @CancerWorldmag
Nice wrap to Phase 1 clinic today.
#1 Continue durable PR on a tonsillar small cell patient. Always gratifying to see durable PR in high grade neuroendocrine patients!!! #TCellEngagers
#2 Not uncommon to see continued tumor shrinkage after PRRT treatment, in fact some RECIST PR happens a year later.
(The way radiation induced tumor kill works) However the most important thing in low grade NETs is durability of stability!! #Theranostics
Now time to work on @myESMO abstracts. Looking forward to visiting Germany!! @OncoThor you up for some beer tasting?
🚨 Context Therapeutics $CNTX Q1 2025 Highlights:
✅ CTIM-76 & CT-95 in Phase 1 trials
✅ $89.4M cash and cash equivalents as of March 31, 2025
✅ Expected cash runway into 2027
#Biotech #Immunotherapy #CancerResearch #TCellEngagers
Read more here:https://t.co/oDLfWQfTB9
🚨 We’re excited to welcome Jennifer Dashnau, PhD, MBA as SVP of Technical Operations at Context Therapeutics!
Welcome to the team, Jennifer! 👏
#Biotech #Leadership #Immunotherapy #TCellEngagers #ContextTherapeutics #Oncology #WomenInSTEM
Janux Therapeutics Initiates Phase 1b Expansion Studies with JANX007 in Patients with Prostate Cancer and Provides Program Updates
Read the release here: https://t.co/BuaMeRYh38
$JANX #TCellEngagers
Wonderful opportunity to #share & #discuss emerging role of #TCellEngagers #BiTEs in management of #SmallCellLungCancer w/ our Malaysian 🇲🇾 colleagues during #LCS2025.
Small group discussions (esp. over a meal! 😋) are always very interactive for experience sharing.
#LCSM @AP@APCLC_2023 @apoddc @CUHKMedicine
If you want to know everything about #Tcellengagers in #prostatecancer check out this excellent review by @ziremozay & @chadihc98 💫
T-cell Engagers in Prostate Cancer, Rapid Review out on European Urology
https://t.co/g5YEucEWb1
T-cell engagers (TCEs) represent a promising therapeutic option for advanced #ProstateCancer , which is characterized by its "cold" tumor immune microenvironment and resistance to conventional immune-targeting therapies.
TCEs work by directing T-cells to attack cancer cells through simultaneous binding to CD3 receptors on T-cells and specific tumor antigens on prostate cancer cells. While early studies in metastatic castration-resistant prostate cancer have shown encouraging antitumor activity, with prostate-specific antigen and radiographic responses, challenges remain. These include immunogenicity, the development of antidrug antibodies, and toxicities such as cytokine release syndrome. Ongoing trials are exploring ways to improve the efficacy of TCEs, including combination therapies and biomarker-driven approaches.
@chadihc98
@ziremozay
@Micah_Ostrowski
@CMercinelli
@ggebraelmd
@nsayeghmd
@umangtalking
@AzadOncology
@EAntonarakis
@neerajaiims
@OncoAlert 🚨 @nataliagandur @bavilima
AbCellera (@AbCelleraBio) Expands @AbbVie Collaboration to Develop T-Cell Engagers for Oncology
https://t.co/EKUtA0eSFj
#Health #Medicine #Cancer #OncoDaily #Oncology #TCellEngagers #Innovation #MedX
#Hematology Cardiovascular 🫀toxicities associated with novel cellular immune therapies #CardioOnc #CARTcell #TcellEngagers #BispecificAntibodies @sehh_es @EHA_Hematology @ASH_hematology @cardiooncoSEC @secardiologia @escardio @ICOSociety @JACCJournals
Cardiovascular toxicities associated with novel cellular immune therapies
https://t.co/liJ8SBHKXn #lymphoidneoplasia
Traditional strategies to use the immune system against cancer are often highly toxic. Masked #TCellEngagers could be a key to finding the intersection between high efficacy and improved tolerability. This is the next wave of innovation in #oncology – we’re ready to lead it.
Janux Therapeutics Reports Second Quarter 2024 Financial Results and Business Highlights
Read the release here: https://t.co/1t8pNyGxuA
$JANX #TCellEngagers
#DYK? Sapient's mass spectrometry-based /𝐃𝐞𝐞𝐩/ 𝐂𝐞𝐥𝐥 𝐒𝐮𝐫𝐟𝐚𝐜𝐞 𝐏𝐫𝐨𝐭𝐞𝐨𝐦𝐢𝐜𝐬 can be used to identify & prioritize tumor-associated antigens (#TAAs) as key targets for #Tcellengagers, measuring up to 1,000 cell surface proteins: https://t.co/vhqWFhUKF4 #Tcells
Thrilled to be heading to my 3rd consecutive AACR! Drop me a message if you want to connect, especially those working with T cell-based therapies!
#AACR24 #Tcellengagers #CARTcells #TcellRx
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