Top Tweets for #sPARKLab
🚨Super-exciting work from our most creative 🪄physician-scientist 👨⚕️👨🔬 @MarcHilmi 🇫🇷 from #sPARKlab 🧪 & @schoenfeld_j 🧑🔬 @MckerrowWilson @bengrbm spearheading ⏩the multi-omic analyses in Precision Immunotherapy #POLAR @MS@MSK_DeptOfMed @PICIatMSK @CpcrMsk @MSKCancerCenter 🇺🇸
Getting to the core immune biology of the longitudinal tumor and blood TCR at single cell and spatial level.
🔗https://t.co/UtCD1C7i4R @NatureMedicine
Invigorating 🔥pre-existing Tumor-Infiltrating Expandable (TIE) T cell clonotypes in exceptional responders with dual PARP-PD-1 blockade in HRD PC
Fascinating story of #spatialTCR offering deep and orthogonal insight from genomically the most ☝️immunogenic 🧪subset of #pancreaticcancer
@CentralParkWMD @TheVinodLab @xrtGenomics @dana_peer @ciacobu @EileenMOReilly
@OncoAlert @oncodaily @OncoDailyGI @OncBrothers
@NatPancFdn @PanCAN @lustgartenfdn
Just back from @AACR and honored to present our POLAR translational work led by the best mentors ever @CentralParkWMD @EileenMOReilly @ciacobu
Using single-cell, spatial transcriptomics & TCRseq, we dissect durable response vs rapid progression in PDAC @MSKCancerCenter
Thank you @myESMO for your kind highlight of this #POLAR study @NatureMedicine
@CentralParkWMD @EileenMOReilly @CatherineaOC @MarcHilmi @ciacobu @bengrbm @TheVinodLab @xrtGenomics
Let's go #sPARKlab @MSK_DeptOfMed
"These results provide a rationale for ongoing randomised studies (e.g., SWOG S2001) and future precision immunotherapy trials that integrate DDR status, neoantigen quality and TME remodelling to improve outcomes in patients with pancreatic cancer."
Huge multidimensional temporospatial datasets for deeper knowledge and science for our patients!
#HumansBeyondPatients #HBP
@CpcrMsk @MSKCancerCenter
https://t.co/XW12Gb4xad
8/n
Grateful to our dedicated patients and families who made this work possible. #HumansBeyondPatients #HBP
Thank you to our clinical research teams, collaborators @MSKCancerCenter and my #sPARKlab mentees.
Thank you @Merck @theNCI @NIH @PICIatMSK @parkericiici @CpcrMsk @MSK_Dep@CpcrMsk @MSK_DeptOfMedOfMed
Philanthropic Funder (The Katz Family)
This work reflects a true team effort, across science, care and community.
Proud to be part of the Fearless #HBP community pushing this field forward.
The journey continues. Stay tuned!
@NatureMedicine @MSKCancerCenter
Proud of this team #sPARKlab riding at @Cycle4Survival clinician-scientists pushing the next wave in pancreatic cancer.
10/n
Fearless #HBP white shades 😎
Proud of this team #sPARKlab riding at @Cycle4Survival clinician-scientists pushing the next wave in pancreatic cancer.
We are finally seeing real momentum:
#KRAS #RAS targeted therapies
⭐️ Smarter immune modulation
⭐️ Biology-informed combo clinical trials
Momentum is here to move the field forward for PDAC
100% of funds go directly to research. https://t.co/9sJbQADdVp
#PancreaticCancer #TranslationalScience
#GI #RAS #Translation #Therapeutics
10/n
Fearless #HBP white shades 😎
Proud of this team #sPARKlab riding at @Cycle4Survival clinician-scientists pushing the next wave in pancreatic cancer.
We are finally seeing real momentum:
#KRAS #RAS targeted therapies
⭐️ Smarter immune modulation
⭐️ Biology-informed combo clinical trials
Momentum is here to move the field forward for PDAC
100% of funds go directly to research. https://t.co/9sJbQADdVp
#PancreaticCancer #TranslationalScience
#GI #RAS #Translation #Therapeutics
Créativité, technologie et enthousiasme au rendez-vous ! 👏
Les élèves de 3e ont conçu et imprimé des objets 3D lors de leur visite à #SparkLab grâce à #Tinkercad
#3DPrinting #EducationInnovante @Hhhsinfo @DidiSaleh10
When your PI presents your work
Calling on you as captain of Fearless #HBP #HumansBeyondPatients #sPARKLab
Breakthroughs with #KRAS inhibitors and immune modulation are near in #PancreaticCancer but we need to learn more & go faster
Ride with us & tell your story to fuel the mission
👉 https://t.co/j0VVs1esQw
Practice-changing contributions and a beautiful narrative of a career dedicated to advancing oncology #GastricCancer #EsophagealCancer
Congrats 🎉 to @YJanjigianMD 🪑#Endowment
Full circle. Her journey began with @DrSDNimer 🌟#GIOnc #Leadership #sPARKLab 💜 @MSK_DeptOfMed
Quietest before the sunrise 🌅
Morning runs 🏃🏻♂️powering the science 🧬 Fantastic collab with Wil & Yuval from @bengrbm on #PDAC #immunology
Big welcome to @nasca_vincenzo joining the #sPARKLab. Momentum is real.
@MarcHilmi @MSK_DeptOfMed
#PancreasWars @FredsTeam
SSSIHL-IIC | Sparklab 2.0 - Start-up Incubation Training Program | Session 14
Speaker: Dr. Shivakiran Makam
Date & Time: 3 Oct 2025, 08.00 PM (IST)
Topic: Grants & Early-Stage Funding
Visit us at: https://t.co/VrI2HmJJ2u
#Sparklab #Entrepreneurship #StartupIncubation #Funding
Post-performance is real after the showtime 🎭 Always good to reconnect with friends in the teamwork for science and clinical impact. Proud to represent the #sPARKLab @CpcrMsk @MSK_DeptOfMed at #AACRPan25 — science, posters, and future collaborations in the making.
Tumor plasticity, stromal rewiring & clonal T cell expansion define response & resistance to PARPi + PD-1i #HRD #PancreaticCancer #POLAR
@MarcHilmi rocked 🎸🤘🏼 - presenting the TCR Infiltrator–Expander #TIE platform - real translational potential.
#sPARKlab #AACRPan25 #PancSM
The beauty is in the eyes of the beholder but we seek, hence we find. POLAR sails boldly across the Charles, charting new waters in PDAC and beyond. Clear skies Smooth currents Eyes on the horizon. ⛵🧬
#POLAR #sPARKlab #AACRPan25 #PancSM #PancreaticCancer @MSK_DeptOfMed @CpcrMsk
La fisión nuclear y la fusión nuclear provee y proveerá nuestra alta demanda energética sostenible. Su divulgación es necesaria. Hablamos con Carlos Hidalgo @cfp_Ciemat y autor de libro reciente con @CatarataLibros y con @pablo_prf del @MIT #SPARKLab
https://t.co/vqAfuh7IlY
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