Jakob Michaelsson

Research group leader at @CIM_Sweden focusing on human immunology with a particular interest in NK cells, ILCs and T cells during development and in tissues.

[Quirin Hammer @QuirinHammer]

Happy to share the final work from my post-doc with @MalmbergLab published in @CellStemCell today https://t.co/ZcC8Q32kts
extensive 15-post-🧵 below

[MalmbergLab @MalmbergLab]

Happy to share our new NK cell resource in @NatImmunol: "Pan-cancer profiling of tumor-infiltrating natural killer cells through transcriptional reference mapping." https://t.co/UzENCpFWMv. @herknet, @AlinePfefferle, @AmirHorowitz @humancellatlas, @CoE_PRIMA, @UniOslo_MED

[Caleb Lareau @CalebLareau]

What a PERFFect day to share our new preprint!

With @tsion_abay #BobStickels @MerilTakizawa @ChaligneRonan and @Satpathology, we introduce PERFF-seq, a new experimental approach to studying rare cells with scRNA-seq via transcript-specific enrichment. https://t.co/woKvdEdOf0 1/n

[Erdinc Sezgin @Sciezgin]

Several amazing PhD positions in Data Driven Life Sciences within national @scilifelab DDLS program. See the details here:
https://t.co/YScHYefB0z

[Jakob Michaelsson @jakmic2003]

Congratulations Vivien - really interesting findings!

[Vivien Béziat @BeziatV]

Out in @CellCellPress today! We describe the first humans with inherited, complete FLT3L deficiency. Despite a lack of most dendritic cells, they reached adulthood. See the thread below for the main highlights of our paper. https://t.co/0jPFLfDRQh

[Alejo Rodriguez-Fraticelli @AlejoFraticelli]

Grades of DNA methylation as the basis of epigenetic cell memory... must-read.
https://t.co/MDBRTzp70c

[Shalin Naik @shalinhnaik]

Very excited (& nervous) to share what we've been working on the past many years. Only took 3 first authors (Schreuder the experimentalist, @DawnSLin the analyst, and @syzmath the modeller) & co-senior Weber (computational, modeller, SynBio extraordinaire) https://t.co/Wnhi6095Rb

[Jakob Michaelsson @jakmic2003]

@BeziatV @ScienceMagazine Congratulations Vivien,was great listening to your talk at CIM about it!

[Ravi K. Patel @sciRPatel]

How do neonates with primitive immune system survive in the world? We found: (1/5) @SciImmunology
(in Rudd & Grimson labs; with Neva & Connor, fellow Tweeters @Oyeb2003 @CybelleTabilas @kristel_yee @eliataitwojno)
#SingleCell #multiomics #neonatalImmunity https://t.co/LwLkNyisj8

[Marty Weissman @marty__weissman]

Excited that paper is published today! Go read "Clonally heritable gene expression imparts a layer of diversity within cell types" at Cell Systems, https://t.co/qiFT8i5xoQ. Thank you to @Jeff_Mold for including me on this project with so many fantastic scientists.

[Jakob Michaelsson @jakmic2003]

Finally!

[kathleenabadie @kathleenabadie]

Do you ever question prior decisions as you gain new information? Do you wonder if immune cells do too? Check out our @Kueh_Lab preprint about a flexible T cell decision-making strategy that enables robust and scalable control of immunological memory https://t.co/e60avVHvBB (1/n)

[Camilla Engblom @camillaengblom]

The Engblom lab is hiring a postdoc and a research assistant !
Come join us to understand B cell clonal dynamics in cancer and beyond.

See specific details below and how to apply:
Postdoc: https://t.co/yjZoIlx9bg
Research assistant: https://t.co/KpaC8Zcma9

[jonatcoquet @jonatcoquet]

Wow. Very cool findings.

[Tak Sekine @SekineTak]

Sekine group is recruiting for curious minds! 🧬🧫🧪🔬Please apply or spread the word 🗣️
https://t.co/D3KVjjDpxv

[Jakob Michaelsson @jakmic2003]

@Qirongliiin @camillaengblom @thrane_kim @Jeff_Mold @FrisenJonas @joalunatkthse Great to see it out - congratulations!

[Camilla Engblom @camillaengblom]

And Spatial VDJ is out! More to follow, but for now, joy and gratitude for the privilege to work with the wonderful @thrane_kim @Qirongliiin @Jeff_Mold @FrisenJonas @joalunatkthse and many more collaborators. @karolinskainst @scilifelab @KTHuniversity https://t.co/3LujYGsCUA

[David Steensma, MD @DavidSteensma]

Did you ever wonder why our marrow is located inside of our *bones*, #MedTwitter? There’s no a priori anatomical reason it should be sited there. Blood cells could form in our spleens & livers, as they do during our fetal lives; or elsewhere, as in some animals. Let’s discuss! /1

[Jeremy Owen @jeremyaowen]

1/ My work on epigenetic memory with @leonidmirny, @osmanovicdino1 is out @ScienceMagazine!

https://t.co/KCr7GR4Hmd

How can *stable* memory be encoded in patterns of *dynamic* epigenetic marks? We find 3D folding of genome can stabilize memory, if 3 ingredients are present...

[NK cell Biology @NKcellBiology]

MetaGate: Interactive Analysis of High-Dimensional Cytometry Data with Meta Data Integration https://t.co/4vcIXz593s