Multidimensional differences in Right vs Left sided Colorectal Ca
R & L CRC differ in tumor biology, clinical behavior & response to targeted therapy
Shifting from sidedness to molecular classification may better guide treatment decisions @OncoAlert
https://t.co/jf7fTbybPg
Expanding the potential of antibody drug conjugates in gastrointestinal malignancies: beyond HER2 targets
@ESMO_Open
https://t.co/0vFQ5kemVh
👏Excellent review on ADCs
👉comprehensive review on MOA, resistance mechanism, old & new targets and future directions
@myESMO
Kidney cancer causes over 150,000 deaths per year worldwide 🌎
Here are a few tips to help prevent it:
1. Don’t smoke 🚭
2. Maintain a healthy weight ⚖️
3. Control blood pressure 🫀
4. Limit alcohol 🍸
5. Healthy diet 🥬
6. Exercise regularly 🏃🏻♀️
7. Regular health checkups 👩🏻⚕️
ENHERTU® Demonstrated Statistically Significant and Clinically Meaningful Improvement in Overall Survival in Patients with HER2 Positive Metastatic Gastric Cancer at Interim Analysis of DESTINY- Gastric04 Phase 3 Trial
👉ENHERTU more effective than Pacli/Ram
https://t.co/TOduG8XVv3
@myESMO
Early-onset colorectal cancer is expected to become the leading cause of #cancer death in ages 20 to 49 in the U.S. by 2030.
Research is urgently needed to better detect and treat patients, argues this #SciencePerspective: https://t.co/3hkt8o9YZE #ColorectalCancerAwarenessMonth
Our latest review on KRAS mutations in early-stage colorectal cancer is out! 🧬
We discuss their prognostic impact, and highlight the importance of routine molecular profiling for better risk stratification and adjuvant therapy decisions.
https://t.co/77I81QcUYt
Total neoadjuvant treatment, Non-operative management and Radiotherapy-free strategies: New approaches for the management of pMMR/MSS locally advanced rectal cancer.
A comprehensive review and evidence-based algorithm
https://t.co/gMAwbmuXiq
A 33 min overview of GI rad onc!
I made this video for an oral boards review course, sharing here.
It’s just 5 slides (below) & me talking the whole time, so you can just listen.
Hope it’s helpful! Link next post, and short 🧵.
04 de febrero | Día Mundial contra el Cáncer
En este Día Mundial contra el Cáncer, unámonos para reescribir el futuro de la atención oncológica, un futuro en el que las necesidades de las personas y las comunidades sean lo primero.
#UnidosPorloÚnico
Trastuzumab with or without pertuzumab for peri-op CTx of HER-2+ GC #ASCOGI25
🔎EORTC-1203 GITC INNOVATION
👉mpRR: 23 vs 37 vs 26%
👉3yr OS rate: 75 vs 76 vs 65%
👉High Tox for CTx + T + P
🧐 Negative trial, but high mpRR by adding T to CTx
@myESMO
That is an excellent point and some food for thought: if pCR is not a good surrogate for survival in GE cancers, what endpoints should we assess, and how should we design future clinical trials?
The reason why PCR is a soft end point in Gastro Esophageal cancer. Especially in studies involving CTRT . Are we chasing the wrong goal post . #GI25 . @ASCO@NiuSanford@KrishanJethwa@5_utr@Larvol