Jesse Pyle

Research scientist @NEBiolabs | @VirologyHarvard grad | Virus replication 🦠 DNA/RNA modifications 🧬 Urban gardener 🌱 He/Him

[Jesse Pyle @jesse_pyle]

Excited to share the latest from the Saleh lab @NEBiolabs

We describe new GTs within bacteriophage-encoded pathways that hypermodify DNA with diverse and complex sugars. As always, viruses continue to amaze!

https://t.co/3zBfxAvmmk

[Jesse Pyle @jesse_pyle]

@Otoole4K @LanaSaleh29 @SynBioSean including Sean here!

[Jesse Pyle @jesse_pyle]

Excited to share the latest from the Saleh lab @NEBiolabs

We describe new GTs within bacteriophage-encoded pathways that hypermodify DNA with diverse and complex sugars. As always, viruses continue to amaze!

https://t.co/3zBfxAvmmk

[Jesse Pyle @jesse_pyle]

Congrats to Sean Lund, @Otoole4K, and @LanaSaleh29 on the next chapter of this exciting project 🎉 And thank you to the wonderful research community at NEB!

[bioRxiv @biorxivpreprint]

Modification of DNA by a viral enzyme and charged tRNA https://t.co/Ee4u65TgXB #bioRxiv

[Science Magazine @ScienceMagazine]

To support early detection of novel #SARSCoV2 variants, researchers developed a model to spot emerging viral lineages together with the mutations that make them transmissible. The approach can prioritize emerging lineages for public health concern. https://t.co/NLXLUOT2fp

[Pardis Sabeti @PardisSabeti]

Friday celebration for @sabeti_lab @MarziehMir & @jesse_pyle as they start exciting next chapters ThankU both for all you contribute the lab and world ✨❤️ #dayboardgaming

[Sean P.J. Whelan @vsv512]

Big news about #NSV2022 in person and coming to you soon. Dust off your passports and come present your most recent exciting discoveries on negative-strand viruses….with a soon to be announced twist! @10queues

[Fodor Laboratory @fodorlab]

In a world where viruses, scientists and llamas co-exist…. happy to share our work in collaboration with Grimes' lab, on mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies produced in llamas. Check it out!
https://t.co/9F79q4hNu0

[Gage Moreno @GageKMoreno]

Check our our new preprint ‼️ Using genomic epi, we show that the #COVID19 outbreak in Provicetown, MA had transmission from & btwn fully vaccinated individuals. @lakrasil points out, the amazing response from local public health and the LGBTQ+ community contained this outbreak💪

[Erica OllmannSaphire @EOSaphire]

On the wall of Gates Found.: If you want to go fast, go alone. If you want to go far, go together. Today in @ScienceMagazine the first results of the global #CoVIC collaboration: from >50 Ab discovery engines across 4 continents, which antibodies retain activity alpha to epsilon.

[Fritz Obermeyer @ftzo]

We used @PyroAi to infer transmissibility of all SARS-CoV-2 lineages based on 2.1 million genomes. Joint work with @glipsnort @jesse_pyle @LubanLab @bronwynmacinnis @PardisSabeti Jacob Lemieux & others @broadinstitute
https://t.co/dCYiL3QKvy

[Eric Topol @EricTopol]

Analysis of over 2 million #SARSCoV2 genomes to determine which mutations drive contagiousness
"Highlighting the key role of non-S (spike protein) mutations, particularly in N, ORF1b, and ORF1a, in promoting increased growth rate." https://t.co/0OFGZdwhZx

[Jesse Pyle @jesse_pyle]

@gogo_science @vsv512 @thelonevirologi 👋

[NOAA Satellites @NOAASatellites]

.@NOAA's #GOESEast 🛰️ is tracking the extremely dangerous Cat. 4 #HurricaneIda, expected to bring a life-threatening storm surge and #hurricane-force winds to the coast of southeastern #Louisiana today.

Updates: https://t.co/arzjJiHnjF
#LAwx #MSwx #Ida #IdaHurricane

[Jesse Pyle @jesse_pyle]

The latest from our arenavirus replication projects in the Whelan lab with @vsv512. A new approach for studying subcellular ribonucleoprotein complexes of Machupo virus. Online now in #JournalofVirology @ASMicrobiology @WUSM_MolMicro @VirologyHarvard

https://t.co/L2g74seDUT

[Jesse Pyle @jesse_pyle]

Excited to be part of this study, out now in #JVI. Highlighting the excellent work of @ajbKreutzberger Anwesha Sanyal @Ravijnk2
@Olli_Vapalahti Giuseppe Balisteri. Many thanks to Tom, @vsv512 and members of the @KirchhausenLab! @JVirology @ASMicrobiology

https://t.co/OXzdjwaXk3

[Kirchhausen lab @KirchhausenLab]

We are hiring! We are looking for a postdoc with expertise in virology and cell biology to study viral entry of SARS-CoV-2 and AAV using advance imaging. Available Now. Please share!
https://t.co/xaEcMEcPJN

[Kirchhausen lab @KirchhausenLab]

Our newest research on drug synergism that inhibit SARS-CoV-2 is online @biorxivpreprint @biorxiv_micrbio. Work in collaboration with Giuseppe Balisteri,@Ravijnk2 , @Olli_Vapalahti at the University of Helsinki. @ajbKreutzberger @jesse_pyle
https://t.co/9i9IW8uo7b

[Sean P.J. Whelan @vsv512]

Ready for #NSV2022? ⁦@10queues⁩