Julie Laffy

Eric and Wendy Schmidt Fellow @BroadInstitute || Systems Bio PhD '23 @WeizmannInstitute

[Jiaqi Zhang @JiaqiZhangVic]

📢 Excited to announce the #ICML2025 workshop on *Scaling Up Intervention Models (SIM)*! Let’s bring together state-of-the-art ideas on modeling novel interventions and distribution shifts. :)

🙌🏻 Submissions are welcome! Link: https://t.co/yLFz3yFOpK

[Sebastiano Cultrera di Montesano @sebacultrera]

Excited to share our latest preprint, introducing the hierarchical cross-entropy (HCE) loss — a simple change that consistently improves performance in atlas-scale cell type annotation models. https://t.co/uX6paEG8k6

[Paul Brennan @Lyonpaul]

Brilliant piece in @NewYorker by @DrSidMukherjee on the causes of cancer and role of cancer promotion, including interviews with @CharlesSwanton and Allan Balmain, and much much more. There's something for everyone, including fans of Sherlock Holmes. https://t.co/FvZRa8V76c

[Yann LeCun @ylecun]

A reasonable policy by Nature about the use of LLMs for paper writing.
- LLMs are tools with accountability and cannot be listed as coauthor.
- LLMs usage should be acknowledged because the transparency of methods is necessary in science.
https://t.co/51f6w6JXyH

[Simon Kuestenmacher @simongerman600]

No country has a more easily recognizable population density as Egypt. The Nile is everything to the nation. Source: https://t.co/07gsbemOVv HT: @researchremora

[Eric Topol @EricTopol]

Cool cover @Nature
Based on discovery that stop codons don't stop but code (in some protozoan organisms)
https://t.co/Own75VMg4Q

[Kevin Cannon @multikev]

The future of email with ChatGPT.

[Anna Obenauf @obenaufa]

Very nice resource by the @TiroshLab that provides access to >70 cancer scRNAseq datasets - collected in one place, annotated and analyzed. https://t.co/Jdlgl4nK4k #EESMetastasis @embl @EMBO

[Elizabeth McKenna @ElizSMcKenna]

Now online in @CD_AACR: Developmental Deconvolution for Classification of #Cancer Origin @garg_lab @kochinstitute @broadinstitute @MGHPathology #cancerofunknownprimary https://t.co/j9YVRyjwyX

[Sam Altman @sama]

Have an idea for DALL·E? Reply with a caption. I'll generate 20 or so!

[Tirosh Lab @TiroshLab]

Excited to share our preprint by @AvishaySpitzer, @GritschSimon, @MarioSuva, Dan Cahill and @KeithLigon5, demonstrating that mutant-IDH inhibitors (mIDHi) act as differentiation therapy in Oligodendroglioma (OG).
https://t.co/lttdXzifDC

[Shai Bel @Mucus_Man]

Being a #newPI

[Mario Suva @MarioSuva]

The 5th edition of the WHO classification of CNS tumors is online today! Great timing with @NeuroOnc 2021 meeting! https://t.co/0VnqkC55FV

[Tirosh Lab @TiroshLab]

We're excited to share our newly published pan-cancer analysis of EMT by Mike Tyler. By integrating single-cell and bulk RNA-seq data, we could characterise EMT and its clinical significance across cancer types, controlling for the presence of stroma. 1/6

https://t.co/eLyjinEcLb

[Roel Verhaak @roelverhaak]

Gradient of Developmental and Injury Response transcriptional states defines functional vulnerabilities underpinning glioblastoma heterogeneity - by my @meyersonlab lab mate Trevor https://t.co/Gi1nr3Q2lI

[Julie Laffy @jlaffy]

Congratulations @alissacg and Gabi Kinker!! Awesome paper :)

[Alissa Greenwald @alissacg]

A thread below on our new pan-cancer scRNA-Seq paper on recurrent programs of heterogeneity across cell lines @NatureGenet co-led with the wonderful Gabi Kinker! With lots of gratitude to Itay and to our co-authors and collaborators including @RotemTal6 and @ZhannieOR.

[Nowakowski_Lab @LabNowakowski]

Excited to share our review of brain development, focusing on what is known about the emergence of cortical areas. Great work by @crcadwell @mohammedmostajo , Aparna Bhaduri and Matt Keefe https://t.co/hNK9L747fN

[DrORourke @DrORourke2]

Big paper with particular importance to #Glioblastoma Congrats to @roelverhaak @mischellab and @HowardYChang

[Sten Linnarsson @slinnarsson]

An excellent and highly recommended improvement on algorithms for estimating RNA velocity of single cells! As usual from @fabian_theis lab with user-friendly software package, clear docs and tutorials.

[Michelle Monje 🟦 @michelle_monje]

What drives the initiation and growth of a lethal early childhood brain cancer with no genomic mutations at all? Paradigm shifting work:

Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma https://t.co/ytCHLLmDrk