Amir Khosrowshahi

Topos Bio

[Mo Islam @moislamvc]

Wonderful time this week at the @ToposBio and @modal JPM event on "small molecules and big computers!"

With their new foundational model Topos-1, the team has been able to characterize disordered proteins in a way that hasn't been achievable before.

Instead of just returning one static protein structure, Topos-1 is able to generate tens of thousands of protein conformations in minutes, at full atomic resolution. Thanks Modal for the computational muscle.

Terrific to see the pharma partner response to the team's data around intrinsically disordered targets for Parkinson's disease and prostate center. Excited for what's to come!

[Amir Khosrowshahi @khosra]

A small but meaningful step forward on the path towards treating diseases like Alzheimer's and cancer.

[ToposBio @ToposBio]

Announcing Topos-1, an all-atom generative model that sets a new benchmark for predicting structural ensembles of intrinsically disordered proteins. Topos-1 outperforms existing models by a large margin, with implications for designing drugs for challenging targets ranging from cancer to neurodegenerative disease.

Read the full technical report on our website: https://t.co/3UtTSdmddf

[Naveen Rao @NaveenGRao]

This was 10 years ago today...the first office of Nervana (founded Feb 25, 2014). Nervana was the first AI chip startup and signaled a sea-change in compute to AI. It represents when compute "went neural".

10 yrs seems long, but the amount of change has been astounding!

[Naveen Rao @NaveenGRao]

Any AI researchers or engineers feeling uneasy about the future, we are hiring at @databricks / @MosaicML !

https://t.co/W9y2SSUZl2

[The Nobel Prize @NobelPrize]

BREAKING NEWS
The Norwegian Nobel Committee has decided to award the 2023 #NobelPeacePrize to Narges Mohammadi for her fight against the oppression of women in Iran and her fight to promote human rights and freedom for all.

#NobelPrize

[Melanie Mitchell @MelMitchell1]

Article in @QuantaMagazine on two of the most brilliant thinkers I know: Bruno Olshausen and Pentti Kanerva:

https://t.co/hQ1fpWhyEm

[Hadi Partovi @hadip]

10 years ago today, @apartovi and I launched @codeorg with the vision that every student in every school should learn computer science. (Thread)

[Amir Khosrowshahi @khosra]

Funny clip of my instructor for Phys 253 and undergrad advisor.

[Leo C. Stein is @duetosymmetry on bsky/threads/🐘 @duetosymmetry]

One of Sidney Coleman's most iconic quotes. Casually lighting up in lecture. Chugging coffee. The cheeky grin and laughing at his own jokes. This lecture had it all! (Will transcribe what he says below)
1/4

[Daniel Green @nu_phases]

I am trying an experiment.

Every day in December, I will post 1 result from the past 40 years (ie 1983-present) that fundamentally changed my corner of (fundamental) physics

Here are my rules
- Nothing already earning a Nobel prize
- Not a ranking, just my preferences

[dara khosrowshahi @dkhos]

After 9 months of full-scale war, the heroic people of 🇺🇦 need our support more than ever. Listen to stories of selfless bravery by Ukrainian drivers & donate now to join them in saving lives. @Uber will match every donation up to $1 million: https://t.co/CO9PyHBkux

[Amir Khosrowshahi @khosra]

A wonderful thought provoking conversation with pioneering neuroscientist Jeff Lichtman on connectomics and many other topics.

[Intel AI @IntelAI]

Listen in on a new episode of Intel on AI with @khosra and Prof. Jeff Lichtman from @harvardbrainsci. Together they’ll discuss researching the physical structure of the brain and its significant contributions to science. https://t.co/Jf01jmkCex

[Intel AI @IntelAI]

Don’t miss this fascinating episode of Intel on #AI. Listen here to host @khosra and @j_a_tucker as they talk about AI in social media and political influence research. https://t.co/94q2Fg3Fsp

[Amir Khosrowshahi @khosra]

A podcast conversation with the wonderful Stanford Prof. @Chelseabfinn and my colleague @mphielipp about meta-learning and other exciting #ai topics. https://t.co/AFo8bBXnls

[Amir Khosrowshahi @khosra]

Douglas Hofstadter in insightful conversation with GPT3 in Economist: https://t.co/8gvJwDdqKZ

[Amir Khosrowshahi @khosra]

Great chat with Prof. Josh Tucker on AI, social media, disinformation for our latest podcast episode. Accompanying blog post: https://t.co/j4nzyPmzHp

[NYU's Center for Social Media, AI, and Politics @CSMAP_NYU]

In the latest episode of #IntelonAI, @khosra talks with @j_a_tucker about using artificial intelligence to study the influence social media has on politics. Listen here:
https://t.co/sYKjFjyHCX

[Amir Khosrowshahi @khosra]

@sama Mathematica

[Amir Khosrowshahi @khosra]

@NaveenGRao You must be worthy to buy it. Maybe no one is worthy. According to the journal of Wall Street https://t.co/eJPXaGvN0K

[Amir Khosrowshahi @khosra]

Great to hear about the amazing research in Prof. Incorvia’s lab @NanoComputeLab. Links to cool things to read from our podcast conversation here: https://t.co/FwXQaeaG4E

[Intel AI @IntelAI]

Hear from Intel’s @khosra and Prof. Jean Anne Incorvia (@NanoComputeLab) about leveraging new physics for computing in a new episode of Intel on AI. Start listening to the podcast here: https://t.co/Uz8K4Lfmac #AI

[Intel AI @IntelAI]

A new episode of the Intel on #AI podcast is here! Join host @khosra and @A_Aspuru_Guzik as they explore the concept of “self-driving labs” and what the future of materials discovery might hold. Listen here. https://t.co/IILTpuGFXT #Chemistry

[Amir Khosrowshahi @khosra]

@NaveenGRao Chili is too conscious.