Lab Leanza

diet, metabolism, cell signalling and organelle contact sites in #cancer @Uni_PD @DiBio_UniPD Interested in #cancer, #mitochondria, #signalling, #contactsite

[FEBS 2024 – Transglutaminases in human diseases @2024TGDisease]

A string of awards ended the #2024TGdisease: Best overall short presentation (60th FEBS anniversary prize), Best presentation for Clarity and Budding Star...but ALL ECRs WERE AMAZING 🤩@FEBSnews

[Lab Leanza @lableanza]

Elisabetta and Filippo presenting their poster at @ISCaM_Society 2024 meeting! 💪👏 #cancer #cancermetabolism #mitochondria

[The EMBO Journal @embojournal]

Apoptotic mitochondrial outer membrane permeabilization MOMP is proinflammatory because of mitochondrial membrane protein ubiquitylation leading to NEMO recruitment and NF-kB activation
Stephen Tait and colleagues @MitosRUs @CRUK_SI
https://t.co/kjbqtEO7Fr

[Molecular Cell @MolecularCell]

Online Now: The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs https://t.co/IKhfXbx8Fh

[Madam Mitochondria @Madam_Mito]

https://t.co/Jb1zL6Z1Ua

Blocking of adipogenic differentiation by #mitochondrial antioxidant may represent a novel strategy to enhance immunosuppressive activity of MSCs in inflammatory microenvironment.

[Journal of Cell Biology @JCellBiol]

.@ShoSuzuki20 et al @CornellMBG reveal a critical role for Vps13-mediated #lipid transfer at ER–endosome contact sites in ESCRT-mediated sorting, elucidating the contribution of the ER to membrane protein sorting at #endosomes https://t.co/RKeslJ12in

#Trafficking #ER_literature

[contactctc @ContactCTC]

Congratulations to @cohenlaboratory (@UNC) for their new paper on dimerization-dependent fluorescent protein probes (ddFPs) to report membrane contact.

This method can be adapted to simultaneously monitor 2 contacts if they share a single organelle.

[Cell @CellCellPress]

Now online! Cell surface RNAs control neutrophil recruitment https://t.co/3ui6UnzXzN

[FrezzaLab @FrezzaLab]

"Motion of VAPB molecules reveals ER–mitochondria contact site subdomains"
https://t.co/2y4bTh1Tg7

[Nature Metabolism @NatMetabolism]

Online now! Metabolic heterogeneity in cancer https://t.co/nml64zKsPi

[Lab Leanza @lableanza]

@FilipovskaLab @TheRackhamLab @telethonkids @ARC_CoESB @CurtinUni @PerkinsComms @gurugav69 @Es_Marcellin @MrEdwardMoh @simpson_kaylene Great work!!!! 👏👏👏

[Aleksandra Filipovska @FilipovskaLab]

Quantitative volumetric analyses and morphological interactions supported by multi-omic profiling identify global organelle defects and mitochondrial dysfunction that can be rescued with ether lipids. https://t.co/nq0vjhVSvS
#FIBSEM #3D #mitochondria #organelles #lipids

[Lab Leanza @lableanza]

@_Alvisilab_ Congratulations

[bioRxiv Cell Biology @biorxiv_cellbio]

Nanobodies as novel tools to monitor the mitochondrial fission factor Drp1 https://t.co/EGonK8Uex7 #biorxiv_cellbio

[Cell Reports @CellReports]

Lipid accumulation-mediated histone hypoacetylation drives persistent NK cell dysfunction in anti-tumor immunity https://t.co/xJU6Xore0U

[Madam Mitochondria @Madam_Mito]

Mitochondria from the Outside in: The Relationship Between Inter-Organelle Crosstalk and Mitochondrial Internal Organization - Jonathan R. Friedman, 2022 https://t.co/c9njls9hhd

[Cell Metabolism @Cell_Metabolism]

New! Online now: Nutrient inputs and social metabolic control of T cell fate https://t.co/Y6senqyr2e

[Nature Reviews Drug Discovery @NatRevDrugDisc]

The first tumour-infiltrating lymphocyte (TIL) therapy for cancer could be approved by the FDA early next year, and a diverse pipeline of other TIL candidates is in development - find out more in our latest news article https://t.co/blKal3nZzY

[silvia @silvia34309683]

WE ARE HIRING!

Looking for enthusiastic PostDocs, and post-master degree, to join our group in Tor Vergata, Rome. Studying mitochondrial dynamics new regulators, and T cells’ cross-talk in the tumor microenvironment. Write me soon, Short deadline!! ([email protected])