Nick Light

Medicine, genomics, science, NBA (Raptors), running, PGY4 in Medical Oncology at @UofT_DOM, MD/PhD @UofTMDPhD (He/him)

[Nick Light @nick_light]

@EricTopol @NatureMedicine Interesting, is there any retrospective data that patients treated with digoxin for cardiac indications have a lower incidence of metastatic cancer?

[Nick Light @nick_light]

@mathepan @CIHR_IRSC Congrats @mathepan !!!

[Valli Subasri @vallisubasri]

✨Check out our study✨We use germline genetic and epigenetic data to identify diagnostic biomarkers, prognostic signatures, actionable therapeutic targets and correlates of clinical heterogeneity that will allow for improved clinical management of LFS patients!

[Nick Light @nick_light]

In the future this holistic approach could be used to develop tailored strategies for cancer surveillance in patients with this rare and devastating cancer predisposition syndrome.

[Nick Light @nick_light]

Amazing work by @vallisubasri comprehensively investigating the ways in which germline genetic variants and epimutations effect cancer risk in patients with Li-Fraumeni syndrome, using whole genome sequencing and methylation data from 396 LFS patients.

[Valli Subasri @vallisubasri]

Multiple germline events contribute to cancer development in patients with Li-Fraumeni syndrome https://t.co/HrNzWHc5ZU

[Nick Light @nick_light]

@vallisubasri used this to develop a machine learning model which can predict cancer risk in patients with Li Fraumeni Syndrome.

[Nick Light @nick_light]

@vallisubasri Congrats Valli!!

[Nathaniel D Anderson @natedandy_PhD]

Happy to share our preview on the spatial organization of microbiota in cancer published in @ImmunityCP.

Original paper by:
@CJohnstonLab1 @BullmanLab @fredhutch
https://t.co/HDSB0UKm9C

[Nick Light @nick_light]

@LMelvinMD @NatureComms Thank you @LMelvinMD !

[Nick Light @nick_light]

Our study is out today in @NatureComms ! We analyzed cancer genomes from patients with Li-Fraumeni syndrome and found early copy number gain of the mutant allele of TP53 to be a characteristic feature of these tumours. https://t.co/QA3zXHTKGG

[Nick Light @nick_light]

@f_buskandar @NatureComms Thanks Fahad!

[Nick Light @nick_light]

@JPablo_Neuro @NatureComms Thanks Pablo!

[Nick Light @nick_light]

@ethanylin @NatureComms Thanks Ethan!

[Nick Light @nick_light]

@NicolaJGI @uoftmdphd Thanks @NicolaJGI !

[Nick Light @nick_light]

@NikitaK_Singh @NatureComms Thanks Nikita!

[Nick Light @nick_light]

@vallisubasri @NatureComms Thank you Valli! So glad we got to work together on some awesome projects!

[Nick Light @nick_light]

Amazing to watch this study grow over the past 7+ years. Congrats to the entire KiCS program!

[Nature Cancer @NatureCancer]

💫ONLINE NOW @NatureCancer – „The clinical utility of integrative genomics in childhood cancer extends beyond targetable mutations” by #DavidMalkin #AdamShlien & Co.
👇
https://t.co/9kVIWAUCCr
https://t.co/9kVIWAUCCr

[Nick Light @nick_light]

@NikitaK_Singh @ccmtoronto Congrats Nikita!!

[Nick Light @nick_light]

@NatashaErinLane @UofT_DoM Congrats Natasha!!

[Naheed Dosani @NaheedD]

Who else thinks that instead of wasting millions of tax dollars on private, for-profit agencies to provide hospitals with temporary nurses...the Ontario government should just provide ALL nurses with proper wages, permanent jobs & benefits? ✋🏾