Otto Chipashvili

🦠🔬 PhD Candidate in the Mougous Lab at Yale
interested in intermicrobial interactions

[Billy Ngo @billymngo]

Been building a genomics viewer with Claude Code for diverse genomic data (TnSeq, RNASeq etc) It’s intuitive, light, and highly customizable for figures or .svg files. If you’ve been looking for an IGV alternative check it out!
Run “pip install bingoviewer” then “bingo”

[Cell @CellCellPress]

Now online! The unique architecture of umbrella toxins permits a two-tiered molecular bet-hedging strategy for interbacterial antagonism https://t.co/KduytumAY5

[Cell Host & Microbe @cellhostmicrobe]

Pseudomonads on GAURD

Mougous @YaleMicroPath describe immune strategy in Pseudomonas, termed GUARD, that protects against bacteria & viruses. Controlled by Gac/Rsm regulatory pathway, program activates suite of defense mechanisms to general danger signal
https://t.co/MzM3vjf0RP

[bioRxiv Microbiology @biorxiv_micrbio]

BetaH proteolysis unleashes an electrostatic-homing antibacterial polymorphic toxin https://t.co/G9PtO9Z8Gg #biorxiv_micrbio

[Otto Chipashvili @ot_chip]

who needs Adobe Illustrator when MS Paint still exists?

[Cell @CellCellPress]

In the latest issue! Neuropeptides specify and reprogram division of labor in the leafcutter ant Atta cephalotes https://t.co/8CYaL7mr1a

[bioRxiv Microbiology @biorxiv_micrbio]

Recognition of unique cell surface glycopolymers by diversified lectin domains specifies umbrella toxin targeting https://t.co/Itt8fJNTgj #biorxiv_micrbio

[Trends in Microbiology @TrendsMicrobiol]

Twists, turns and jumps: T6SS evolution within species https://t.co/KnYlJOmfjE

[Yale West Campus @YaleWestCampus]

We are delighted to welcome Joseph Mougous to the Microbial Sciences Institute. An international leader in microbiology and HHMI Investigator, Mougous joins the faculty @YaleMicroPath later this year. https://t.co/xjkQpBdpOs

[bioRxiv Microbiology @biorxiv_micrbio]

Pseudomonads coordinate innate defense against viruses and bacteria with a single regulatory system https://t.co/EJmWwpNldF #biorxiv_micrbio

[Patrick Collison @patrickc]

Biology papers be like "The nucleus is part of the cell and contains a lot of DNA. Polycomb Repressive Complex 2 (PRC2)-mediated deposition of H3K27me3 establishes domains of facultative heterochromatin, silencing gene expression in a developmentally regulated manner."

[Ming "Tommy" Tang @tangming2005]

🎯 Do you really understand p-values?
The p-value histogram can reveal a LOT about your data. Let's break it down using real examples.👇

[Nature Microbiology @NatureMicrobiol]

The enigmatic, ultrasmall and largely uncultivated Candidate Phyla Radiation bacteria represent a treasure trove of potential discoveries, argues this recent Perspective in PNAS🕵️👇 from the Mougous Lab @UW
https://t.co/7I69NhYeGj

[Otto Chipashvili @ot_chip]

New review on the 'microbial dark matter' that is Patescibacteria
https://t.co/OpOmhAE9rs

[Science Magazine @ScienceMagazine]

Bulky pastas—like farfalle and fusilli—require more packaging than thinner varieties, making them trickier to transport and leading to more waste.

🍝 On #NationalPastaDay, learn more about a different twist on pasta dough that could help reshape food manufacturing, according to a @ScienceAdvances study. https://t.co/3zVEME9yQS

[The Nobel Prize @NobelPrize]

BREAKING NEWS
The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”

[Itai Yanai @ItaiYanai]

Doing good science is 90% finding a science buddy to constantly talk to about the project.

[alex meeske @alexjmeeske]

The final version of our paper on anti-CRISPRs "in disguise" as Cas proteins is out today in Nature! Congrats to Mark, Edith and the whole team! https://t.co/e1SmItuSIQ

[Otto Chipashvili @ot_chip]

one of my favorites is the paper that just put in a capital T for error bars

[Otto Chipashvili @ot_chip]

This is so good!

[Tim Davison ᯅ @timd_ca]

We’re thrilled to announce CellWalk for iPhone and iPad! 📱✨ Journey to the atomic level and explore the molecular machines of a bacterial cell.

We’re building the future of biology education—it’s interactive and immersive.

https://t.co/4UM8X8PYr9

#Apple #iPhone #iPad #scicomm #BiologyApp #STEM #EdTech #gamedev

[Otto Chipashvili @ot_chip]

@BioRad your DNA is backwards