Pengcheng Zhou

#Immunology immunologist @NussenzweigL @RockefellerUniv | Views are my own

[Pengcheng Zhou @pchengzhou]

Pleased to share that our work on late-invading germinal center B cells is now online in @ImmunityCP. By developing a new dual-recombinase fate-mapping reporter system, we show that late-entry B cells in established germinal centers preferentially contribute to the memory B cell.

[Immunity @ImmunityCP]

Online now: B lymphocytes that enter the germinal center late preferentially differentiate into memory cells that recognize subdominant epitopes https://t.co/oveMvvnwA5

[Euan Arnott @Nucleocapsoid]

This is both clever work - and potential REALLY useful knowledge to optimize vaccine timing for highly mutable viruses like SARS-2 & influenza, where sub-dominant epitopes are (IMHO) desirable targets to produce more "future-proof" antibodies.
@snpoehlm

[Brianna Naizir @BriannaNaizir]

Excited to share our new paper! Huge thank you to my amazing mentor Andrea @SchietingerLab and our co-authors for the guidance and support along the way! https://t.co/VDmoZnqwgO

[Immunity @ImmunityCP]

Online now: B lymphocytes that enter the germinal center late preferentially differentiate into memory cells that recognize subdominant epitopes https://t.co/oveMvvnwA5

[Waggoner Lab @LabWaggoner]

B lymphocytes that enter the germinal center late preferentially differentiate into memory cells that recognize subdominant epitopes @ImmunityCP
https://t.co/YC4VDI6Oa4 @NussenzweigL @RockefellerUniv @pchengzhou

[Scott Mueller @SMuellerLab]

Our eyes are amazing - especially because they are protected by many immune cells. Learn more in our new review in @NatRevImmunol with @DrLauraDownie @holly_chinnery @Mengliang_Wu @UniMelb @TheDohertyInst
https://t.co/sHF3H9iVqu

[Pengcheng Zhou @pchengzhou]

@rohamparsa @ssmfgrants @karolinskainst Congrats!🎉 Well deserved!!

[Pengcheng Zhou @pchengzhou]

@XinGao_JCSMR @SciImmunology @JCSMR @ian_cockburn Congrats Andy! Great paper on ABC🎉

[Pengcheng Zhou @pchengzhou]

@c_gaebler @ChariteBerlin Congratulations & well-deserved!!

[Alex Chudnovskiy 🇺🇦 @ChudnovskiyLab]

I'm delighted to share that I'll be joining @TheCrick as a group leader in spring 2024. Our lab will focus on tumor immunology, antigen presentation, and immune cell-cell interactions using LIPSTIC.

If you're interested, I'll be hiring postdocs and PhD students. Get in touch!

[Spencer Chen @spencertchen]

Pleased to share our work in @ImmunityCP, where we studied the role of B cell receptor (BCR) signaling in germinal center B cell selection. We developed two tools to investigate this question: a tracker of BCR-antigen engagement in vivo and a BCR inhibitor-resistant mouse model.

[Pengcheng Zhou @pchengzhou]

@LabPhan @AbigailGroot129 @wunniess @GarvanInstitute @UNSWMedicine @CellCellPress @UniofOxford @UQMedicine @tanmay_mitra_ @Helmholtz_HZI Congratulations!🎊🎉

[Phan Lab @LabPhan]

1/ So proud of PhDs @AbigailGroot129 & @wunniess @GarvanInstitute @UNSWMedicine their first paper now out @CellCellPress. Amazing collab with Veera Panova & Oliver Bannard @UniofOxford, David Hume @UQMedicine, @tanmay_mitra_ @Helmholtz_HZI & many more.

https://t.co/TNLIJ4xeFl

[Journal of Clinical Investigation @jclinicalinvest]

Protein vaccine NVX-CoV2373 elicits functional T cell immunity: https://t.co/J5HKvR0kSg
In this #Commentary, @PC_immuno highlights the immune response following NVX-56 CoV2373 vaccination and the possibility of expanding the T cell response.
Related: https://t.co/2RHZ4jVnDL

[Pengcheng Zhou @pchengzhou]

My pleasure 😄 Excellent work by @profshanecrotty and team @ljiresearch Check this out! @jclinicalinvest

[Prof. Shane Crotty @profshanecrotty]

Our new paper is out showing T cell responses to the Novavax vaccine, studying Novavax vaccine clinical trial participants, led by the outstanding Dr. @CModerbacher! With a nice commentary article by @PC_immuno . 🧵

https://t.co/3OCJ9Ix5GB

https://t.co/F50tw6a1kZ

[Prof. Shane Crotty @profshanecrotty]

As usual, @EricTopol beat us to tweeting about our paper. 😂

[Eric Topol @EricTopol]

The @Novavax vaccine induces robust T-cell immunity
Commentary https://t.co/QsvLraIIuN @jclinicalinvest by @PC_immuno @RockefellerUniv
Original research by @ljiresearch https://t.co/izdImxBi6G
@profshanecrotty and colleagues

[Pengcheng Zhou @pchengzhou]

Thanks @jclinicalinvest for the invitation to contribute a commentary article on the T cell immune response elicited by @Novavax vaccine. Excellent work done by @profshanecrotty and team @ljiresearch . Thank you for sharing the work @EricTopol ! @RockefellerUniv

[Eric Topol @EricTopol]

The @Novavax vaccine induces robust T-cell immunity
Commentary https://t.co/QsvLraIIuN @jclinicalinvest by @PC_immuno @RockefellerUniv
Original research by @ljiresearch https://t.co/izdImxBi6G
@profshanecrotty and colleagues

[Journal of Experimental Medicine @JExpMed]

Memory B cell responses to Omicron subvariants after #SARSCoV2 mRNA breakthrough infection in humans. A new study from Zijun Wang @VinciZijun, @PC_immuno, @FraukeMuecksch, Alice Cho et al @RockefellerUniv: https://t.co/QZLK8PVxCw
@NussenzweigL @PaulBieniasz @theodora_nyc #COVID19

[RafiAhmedLab @rafiahmed_lab]

Check out the newest work published @Nature from our lab by Masao Hashimoto showing that the combination of IL2 and PD1 blockade modifies the CD8 T cell exhaustion program.
1/🧵
https://t.co/kXORai69KL