Out today in @NatureGenet!
Important new updates to the Polygenic Score (PGS) Catalog, & a new software tool that simplifies the calculation of polygenic scores in the context of genetic ancestry
👉 https://t.co/0OR1Lw7m0Z
@iamslambert @minouye271 @sritchie73@Florent_Yvon
Over and over again, modern behavioral genetics studies have revealed how flawed the assumption of "equal parts nature and nurture" has been. But the myth remains embedded in the conventional wisdom because numbers in the middle feel intuitively "correct".
Our latest research on the combined impact of genetics and infection on the risk of cardiovascular disease https://t.co/7UVrMRtR5d @epflSV@CHUVLausanne
Pls RT! Great opportunity to attend a Summer School exclusively focused on AI & machine learning for healthcare! Offering talks, a mentorship program, student mini-projects, roundtables, networking & an online exhibition. 5-9 Sept. Learn more: https://t.co/U9YT6rznQW @minouye271
join me & @EricJCGalvez with the rest of the @Roche's pRED microbiome team in Basel to intertwine human genetics & microbiome! open postdoc position here https://t.co/V2WWV7RVDt
Very pleased to share this exciting new work, a highly collaborative effort, on the development, validation and application of genetic scores for a wide range of multi-omic traits.
Preprint: https://t.co/TTH6MV1P7p
Online Portal: https://t.co/KTTrt7r8uJ
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Pleased to announce our recent work is now live @CellGenomics, in which we show machine learning optimized polygenic scores for blood cell traits can stratify sex-specific trajectories and identify genetic correlations with disease.
https://t.co/8q2jwXHb7c
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Pleased to announce our latest work is now live at Nature Metabolism (@natmetabolism), in which we show polygenic risk scores (PRS) can be used to identify novel and causal proteins underlying disease risk.
https://t.co/Re4PnSgwUy
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We studied microbiome dynamics in 245 FMT cases across 13 studies where fecal transplants were used to treat patients who suffered from rCDI, IBD, Metabolic Syndrome, Drug-Resistant Pathogen colonization, or went through ICI anti-tumor therapy.
https://t.co/afA0KoDJF7
Super excited to release https://t.co/CsJaykgnSp, a web application for browsing association results for 3,700 phenotypes across 281,850 individuals from the UK Biobank. The site features plots, tables, and controls for exploring billions of associations.
Happy to finally share this manuscript - large-scale Crohn's exomes from IIBDGC demonstrates complementarity of GWAS and exome findings and many new CD genes. Unlike neurodev - most signal from more common low-frequency variants https://t.co/SM7VACOpql
@konradjk less than a minute spent browsing genebass is needed to understand what a tremendous resource this is for human genetics. a prime example of how science should be disseminated. huge congrats and thanks to everyone involved into making this!
We're thrilled to release a manuscript on rare variant association testing on the exomes of 300k individuals in the UK Biobank https://t.co/Kgyc9Vk7Nq and a browser of the results: https://t.co/c8PJajiHK3