Chronic and acute pain neural pathways distinguished –now chronic pain-specific drugs can be developed without dulling other senses
📷 Xiaoke Chen lab - Qian Wang, Joo Han Lee & Gregory Nachtrab et al @Stanford in @Nature
➡️ https://t.co/1KWhJhDnVw with @rooph
ZEB2 protein vital for ureter development – ZEB2 mutations underlie urinary tract dysfunction in Mowat-Wilson syndrome
📷 Sudhir Kumar et al @BUMedicine in @PLOSGenetics
➡️ https://t.co/V7DNbdyxqQ with @AntDLewis
3D tissue clearing approach called DeepBone enables visualisation of human mesenchymal stromal cell bone marrow niche – differences in young & aged revealed
📹 Nelson Tsz Long Chu et al University of Gothenburg in @natBME
➡️ https://t.co/vPnXVAjB6q
Directed Blast: Axolotl limb regeneration study reveals how the process is driven by cells with different positional identities
📷 Sakiya Yamamoto et al @okayama_uni in @eLife
➡️ https://t.co/6lSfggOVG3 with @DrJohnAnkers
Leaf it Out: Nanofilm 'imprint' analysed by mass spec – a new approach for detailed 'imaging' of chemicals and biomarkers
📷 Yizhu Xu & Xinzhou Wu et al, South China Agricultural University in @ScienceAdvances
➡️ https://t.co/LwdSFXnFZP with @DrJohnAnkers
Epidermal rete ridges correlate with less hairy skin but what's the relationship? This study details how rete ridges aren't directly coupled to hair development
@LeicaMicro microscopy
📷 Sean M. Thompson et al @WSUPullman in @Nature
➡️ https://t.co/Z8ikplixlR
Why do some mammals grow dense fur while others don’t? A new study shows how epidermal rete ridges form after birth and are not linked to hair development. Image captured with a Leica Microsystems microscope. https://t.co/Tj09EbxRhA
@BPoD_s@BiochemOxford
NEK7 protein–'traffic warden' in liver cells keeping energy flowing in the right direction, warding off fibrosis-causing oxidation
📷 Zhenzhen Sun & Le Sun et al Children’s Hospital of Nanjing Medical University, in @NatureComms
➡️ https://t.co/06yaERh5G2 @AntDLewis
Mechanisms to overcome instability in early embryo cell division differ in zebrafish & fruit flies: species-specific mechanisms orchestrated by cytoskeletal microtubules in both
📹 Melissa Rinaldin et al, TU Dresden in @Nature
➡️ https://t.co/9ovNuwQAZE
Fruit fly study finds enzymes Hip14 & Patsas limit lysosome formation & fusion so protecting against Huntington's disease-like symptoms
📷 Győző Szenci et al, Eötvös Loránd University, in @PLOSGenetics
➡️ https://t.co/hbvP7PzBil with @AntDLewis
Human liver tissue with & without fibrosis reconstructed at cell level in 3D - insights for understanding liver disease & how to treat it
📹 Wesley B. Fabyan & Chelsea L. Fortin et al @kellystevenslab@UW in @ScienceAdvances
➡️ https://t.co/y5xJll9BwM
Fuel Line: Transfer of mitochondria from glia to adjacent sensory neurons in dorsal root ganglia – protects against nerve degeneration & pain
📷 Jing Xu et al @Duke_Anesthesia@DukeHealth in @Nature
➡️ https://t.co/lOgqFPpLGD
Mouse life-time brain-wide map of myelin-producing cells and myelin density in health and disease
📹 Yu Kang T. Xu, Abigail Bush & Ephraim Musheyev et al @HopkinsMedicine in @CellCellPress
➡️ https://t.co/xhI2RtgPst
Sensory neurons play a key role in type 2 immunity – the response to parasites and in allergy
📷 re paper by @wenzhang1120 & @immunologyliz et al Artis Lab @WeillCornellGS published in @Nature
➡️ https://t.co/cXV2eDqR1u with @rooph