Solal 🇫🇷

PhD candidate at @PCTGenomics.

[Simona Cristea @simocristea]

I need to raise awareness about an important point in #scRNAseq data analysis, which, in my opinion, is not acknowledged enough:

‼️In practice, most cell type assignment methods will fail on totally novel cell types. Biological/expert curation is necessary!

Here's one example👇

[Solal 🇫🇷 @solal_sc]

@Jack_Geng_Wang Bonne chance pour ta présentation :D

[Mark Milner @MarkMilner96]

Delighted to have this labour of love finally out! 😁 Thanks again to all involved ⁦@grace_pamo⁩ ⁦@CarolineLHolley⁩ ⁦@s_burgener⁩ ⁦⁦@inflammasomelab⁩ ⁦@liviugbodea⁩ ⁦@AustraliaGoetz⁩ ⁦@STARProtocols⁩ #microglia https://t.co/QyV4I95QJb

[Joseph Powell @drjosephpowell]

Our work “Single-cell eQTL mapping identifies cell type-specific genetic control of autoimmune disease” just published in @ScienceMagazine. The work started with the creation of the OneK1K cohort, consisting of scRNA-seq data on PBMCs from ~1000 donors https://t.co/Uzskay7TeM 🧵

[Beilei Bian @BeileiBian]

Happy to see our paper published in @braincomms 👉https://t.co/x3j9Dh5jf6 In this paper, we looked at the associations between genetic variants in MHC region (HLA alleles and C4 copy number) and brain imaging phenotypes. Thanks to @mcraelab @WrayNaomi @BaptisteCouvy !!

[Solal 🇫🇷 @solal_sc]

@doyouseewhy @CellCellPress Congratulations! Impressive work, as usual 😃

[NimwegenLab @NimwegenLab]

You only know what your measurements say about your system to the extent that understand the noise in your measurements. This applies especially to scRNA-seq data, which is subject to severe sampling noise. See here our attempt at solving this problem: https://t.co/9SynpyPC3W 1/n

[JAMA Psychiatry @JAMAPsych]

Lower genetically-determined angiotensin converting enzyme (ACE) mRNA and protein levels are associated with increased risk of schizophrenia, warranting investigation into the role of ACE and effects of ACE inhibitors on patients with schizophrenia https://t.co/IV0hWalrO2

[YEDA WU @yeda_wu]

Peptic ulcer disease (PUD) GWAS paper out. https://t.co/ozLRPqOhrS

[Solal 🇫🇷 @solal_sc]

For anyone who got affected by COVID19 in Australia:
We are recruiting for a study trying to capture variation between people in symptoms and link that to DNA and/or antibody differences.
https://t.co/69rYKDmDHA
#covidozgenetics #covid #naomiwray #imb

[Abdel Abdellaoui @dr_appie]

The estimated shared genetic effects between several Covid-19 outcomes and a wide range of heritable traits.

(the estimated genetic effects for the Covid-19 outcomes come from the January 2021 release of @covid19_hgi)

[Graham Murray (@gkmurray.bsky.social) @gk_murray]

"From Basic Science to Clinical Application of Polygenic Risk Scores - A Primer"
It was a pleasure to contribute to this collaborative work led by @WrayNaomi with Tian Lin @John_J_McGrath @J9_Austin @ian_hickie Peter Visscher @PCTGenomics https://t.co/Ed9iNIiJrc

[Solal 🇫🇷 @solal_sc]

Currently at the "Run the same code, hope for a different result" stage of my PhD.
#phdchat #AcademicChatter #AcademicTwitter

[Annastacia Palaszczuk @a_palaszczuk]

This time last year Queensland had already recorded 36,874 flu cases.

As of August 10 this year, we've only recorded 5,918 – a massive 84% drop.

It's the result of our social distancing, hand hygiene, and staying home when we're sick.

Keep it up, Queensland.

#COVID19Aus

[Abdel Abdellaoui @dr_appie]

Great review from @BaselmansBart, Loic Yengo, @wrheenen, and @WrayNaomi, comparing heritability estimates and genetic correlations from psychiatric disorders based on SNPs with those based on family relationships: https://t.co/HUfPuGKGEC

[Deborah Barros Leal Farias @debfrombrazil]

This is one of most AMAZING tools for academics I've seen in a long time 😮😮
#AcademicChatter
https://t.co/P62kYt8Eg9

[Stephanie L-P @s_rockstone]

If you are in academia ie. #AcademicTwitter , please spend time reading through #BlackintheIvory

And please think about what can you do to change what's happening.

Thanks

[Solal 🇫🇷 @solal_sc]

@itsmedipsikha @AcademicChatter Sorry, I wasn't clear. Australia is not available in the Location tab, I was wondering why.