Matteo Fabbri

Assistant Professor at the Center for Functional Anatomy & Evolution, School of Medicine, Johns Hopkins University

[Ali Max Erturk @erturklab]

Single-cell RNA-seq transformed biology, but we still sample <0.001% of an organism.
2D sections lose 3D context.
What if we image the whole body first?
We Introduce DISCO-seq🤩: full 3D imaging then scRNAseq👇🏻https://t.co/kYkzAWBxUB
by @HarsharanBhatia, Laurent Simons et al.

[nature @Nature]

Nature research paper: Lineage and organ signals sequentially build organ intrinsic nervous systems
https://t.co/V87bLVLjsR

[Armita R. Manafzadeh @armanafzadeh]

Our work on mammalian hallucal grasping, led by Irene Montañez-Rivera during her time in the Nyakatura group, is out now in iScience. A true team effort; thanks to the whole crew for inviting me to contribute a small piece! https://t.co/yYEmau4V6H

[Ali Max Erturk @erturklab]

I am happy to share our protocol paper for wildDISCO technology, a platform for whole-body immunolabeling, clearing and 3D imaging of intact mice at cellular resolution using standard IgG antibodies. https://t.co/f4R8DN0MqZ

This work presents technical details for wildDISCO (Mai&Luo...Ertürk, Nature Biotechnology, 2023, https://t.co/pL6VgT9nF0. The protocol enables deep antibody penetration across the entire body, including challenging regions such as bone marrow, spinal cord and deep organ tissues.

With this approach, we can now map neuronal, vascular, lymphatic and immune systems across the whole organism and study disease processes, cancer metastasis, microbiome interactions and systemic biology in unprecedented detail. The workflow also integrates light-sheet imaging, virtual reality visualization and online atlas generation.

Work led by @jieluo692, @HongchengM . We hope this protocol helps many labs worldwide explore biology at true organism-wide scale.

#DISCO #Clearing #NatureProtocols #SpatialBiology #Imaging #TissueClearing #LightSheetMicroscopy #SystemsBiology #AI #Neuroscience #CancerResearch #wildDISCO

[IPC7 @IPC7_]

✨ We are thrilled to have 6 fantastic plenary speakers at IPC7 in Cape Town!

Today we’re excited to introduce Dr. @jasmina_wiemann from PaLEO Lab in the Department of Earth & Planetary Sciences at Johns Hopkins University, USA, who will be one of our plenary speakers.

[Dr. Jasmina Wiemann @jasmina_wiemann]

Join us at AbSciCon and/or reach out for opportunities in the lab!

Here's the link to our lab homepage:
https://t.co/BXu9eJ5G5e

[Haikuo Li @HaikuoLi]

Check out our recent work on @NatureComms! Greatly appreciate my mentors and collaborators making this possible. We developed epi-Patho-DBiT, a unified platform that enables spatially resolved ATAC -seq or CUT&Tag analyses in FFPE tissues!

[Denis Wirtz @deniswirtz]

Download our updated database of postdoc fellowships from different foundations and agencies.

We identified 275 fellowships. For each entry, we provide description of the fellowship, focus, amount, deadline, eligibility, etc.

Download this database here: https://t.co/EbTahdzbkp

[Prof. Anjali Goswami FRS @anjgoswami]

Job alert! Join my team @DefraGovUK in a critical science leadership role to ensure robust evidence underpins decisions on nature, climate, pollution, food & more. Apply if you thrive on solving big, complex challenges & want to make a real difference! https://t.co/fEWQ6t9mWy

[Fernando Blanco @FernandoBlancoS]

Thrilled to start today as a Severo Ochoa Fellow at the Doñana Biological Station @ebdonana ! !
Over the next three years, I will study the macroecological evolution of vertebrate faunas across deep time 🌍🦴

[Developmental Biology @Dev_Bio_Journal]

#DBfeature

POGLUT2/3 mediated EGF O-glucosylation promotes separation of digits 2 and 3 by influencing fibrillin network reorganization, signaling, and cell dynamics

by Sanjiv Neupane, Bernadette Holdener et al.
https://t.co/fNz1Fj5fXq

[Thomas R. Holtz, Jr. 🦖💕 (he/him) @TomHoltzPaleo]

More diverse than expected: osteohistology of non‐crocodylomorph Pseudosuchia from the Triassic of South America - Ponce - 2026 - Palaeontology - Wiley Online Library https://t.co/O2LYvCZzS7

[Dr. Alexander Ruebenstahl @ARuebenstahl]

Hello Everyone! I am extremely excited to announce that I will be defending my PhD Dissertation on April 27th, 2026.

Years of hard work and the support of a fantastic community of colleague, friends and family have brought me here.

[Denis Wirtz @deniswirtz]

Mapping of vasculature and nervous systems networks in whole organisms (rhesus macaque, mouse, turtle).

They display the same self-similar fractal geometry across species and development stage.

Fractal dimension of 3 for vasculature
Fractal dimension of 2 for nerve networks

[Denis Wirtz @deniswirtz]

3D single-cell maps of embryos reveal "universal" geometry of blood vessels and nerves.

More here: https://t.co/LqZrO7Wnfp

[Dr. Jasmina Wiemann @jasmina_wiemann]

New paper out by Izidio et al., involving @marihaase:

Crocodylomorph dietary versatility has implications for metabolic capacity ... if we could just extract metabolic signals from teeth 🐊

Link: https://t.co/hlwrLUeYHI

[Thomas R. Holtz, Jr. 🦖💕 (he/him) @TomHoltzPaleo]

Decoupled phenotypic constraints framed by respiratory adaptation in the rise of land vertebrates | Science Advances https://t.co/fKYYpHqJZB

[Ali Max Erturk @erturklab]

We are hiring a Lab Technician/Scientist at @DeepPiction

At Deep Piction, we work on medically unmet challenges using high-resolution whole-body imaging with AI. To make this possible, we need strong wet-lab execution.
🔗 APPLY HERE: https://t.co/UDm260qQKz

This role will support the team across diverse experimental workflows and help ensure that our work is reliable, reproducible, and scalable.

If you enjoy hands-on lab work, structure, and making things run properly, this could be a great fit.

📍 Munich, on-site

At Deep Piction, we work on medically unmet challenges, including infectious diseases and cancer. We combine high-resolution whole-body imaging with AI to develop the most targeted and precise therapies.

To make this possible, we need strong wet-lab execution.

This role will support the team across diverse experimental workflows and help ensure that our work is reliable, reproducible, and scalable.

If you enjoy hands-on lab work, structure, and making things run properly, this could be a great fit.

📍 Munich, on-site

If someone comes to mind who would be a great fit, I’m sure they would be excited to see this opportunity, please feel free to share.

If someone comes to mind who would be a great fit, I’m sure they would be excited to see this opportunity, please feel free to share.

[PNASNews @PNASNews]

How powerful was the sense of smell in extinct mammals—even the ancestors of today’s whales? 🐋
By combining fossil skulls + genetic data, researchers uncover how scent shaped evolution.

🎧 Listen now: https://t.co/NrpqEAd6rf

[@LaBonneLaB @labonnelab]

Most people do not understand how todays science and tomorrows cures are being gutted. In the current fiscal year the National Cancer Institute has awarded only 85 grants rather than the HUNDREDS that would normally be awarded by this time.