Kevin Thurley

Analyzing the complex relationships among immune cells with mathematical tools, @UniklinikBonn @ImmunoSens @HCM_Bonn @IEO_Bonn

[Jae Kyoung Kim @umichkim]

A new study shows how math can reveal hidden cancer cell strategies. By using a math model, researchers found that DNA-damaged cells often skip division and undergo polyploidisation—a survival response missed by observation alone.
https://t.co/8CZdg23Bra

[Prof. Nikolai Slavov @slavov_n]

The distribution of ~ 2 trillion immune cells in the human body.

[Charité - Universitätsmedizin Berlin @ChariteBerlin]

Researchers at #CharitéBerlin, @drfz_Berlin and @MDC_Berlin have identified the immune cells that cause severe kidney inflammation in #lupus. The study, published in @nature, could pave the way for future antibody therapies.
https://t.co/1VYCdBPBPC

[Kevin Thurley @ThurleyLab]

The attached cell-based simulation framework for cytokine reaction-diffusion systems uses the finite element solver fenics, and is fully open source and ready to use.

[Kevin Thurley @ThurleyLab]

Excited to share our analysis of cytokine communication using a new 4D simulation environment. Without spatial inhomogeneities, cytokine signals are basically ineffective! The spatial distribution depends on receptor feedback and tissue architecture. https://t.co/Qro9wVVnIj

[Nature Portfolio @NaturePortfolio]

.@naturemethods has increasingly focused its attention on methods development in immunology and presents a special issue that highlights methods and technologies that have galvanized immunological research.
Editorial: https://t.co/MbyN0saugc
Issue: https://t.co/DryhWAFfpC

[Uri Alon @UriAlonWeizmann]

Just did a group meeting of a PhD student in the cloud. It takes courage to say I'm stuck, confused, discouraged. This vulnerability elicited solidarity and support from the group, and a flood of new ideas and hope. It was gratifying for everyone.

[Mohit Kumar Jolly @mkjolly15]

Glad to share work led by @Sarthak_Sahoo_ showing an increased prevalence of hybrid E/M state and higher heterogeneity in basal breast cancer, now out in @iScience_CP. Grateful to our collaborators @c_chaffer @JSomarelli & Jyothi S Prabhu @StJohnsResearch.
https://t.co/gXRwE1IxO5

[European Society for Spatial Biology @SpatialBio]

European Society for Spatial Biology (ESSB) is here, finally! ESSB is a recently founded scientific society dedicated to advancing research in the emerging interdisciplinary field of spatial biology. This is the perfect spot for spatial enthusiasts! Come join us!

[Jae Kyoung Kim @umichkim]

Collaborative work with the Yoshitane group!

Phosphorylation of DNA-binding domains of CLOCK–BMAL1 complex for PER-dependent inhibition in circadian clock of mammalian cells https://t.co/FhmXYkHszq

[Nature Methods @naturemethods]

The immune system is a uniquely dynamic environment. In a Comment, @mathematista discusses how custom-built mathematical models should complement experimental approaches to make immune kinetics more predictable.
https://t.co/LfDL4NEcVR

[Mohit Kumar Jolly @mkjolly15]

Plz RT @biopatrika @IndiaBioscience @DynamicsLiving @physics_living @SMBMathOnco @GibinPowathil @vj_rajagopal @asharmaiisc @BalashaLab @DNagrathLab @pearce_maths @molab_uclm @jishnu1729 @rrockne @lab_craig @ThurleyLab @umichkim @sidharthagoyal @MathCancer @mathoncbro @DagmarIber

[John Tsang @tsanglab.bsky.social @TsangLab]

Our paper @ImmunityCP reveals a human baseline setpoint state (ie, "temperature" under which immune responses are initiated) linked to better responses to flu vaccination resembles cell states induced early and uniquely by the AS03 adjuvant. 1/n

[Mohit Kumar Jolly @mkjolly15]

Glad to share our mini-review on role of computational models in understanding T-helper cell plasticity, led by @PradyumnaVH @TheAviatorFrame @BE_IISc
https://t.co/9fy4ya5m1X
@Systems_Immunol @hongtian162 @ThurleyLab @bhanwar_p @smb_imin @Annaerial @sidjhun @biopatrika @InSDB_79

[Dagmar Iber @DagmarIber]

#SimuCell3D is now out in @NatComputSci https://t.co/yMPicxgA9R -

Massive thx to the editor Fernando Chirigati @fchirigati for handling our manuscript so well!!

The source code is available free online:
https://t.co/Npvhr8eF3l

Can't wait to see it used!! #openscience

[John Tsang @tsanglab.bsky.social @TsangLab]

Enjoying the company of colleagues and friends @teichlab @BockLab Kevin Thurley, Jonathan Badger @BanffNP while attending the fantastic #KSSystemsImmune24

https://t.co/lTgxgYM80W

[Michael Hölzel @HolzelMichael]

Congrats to @egbawden & Thomas Gebhardt to this amazing work on #melanoma #immunity. Fantastic collaboration within @BonnMelbPhD. Thanks to @dfg_public @UniMelb @UniBonn

[GreiffLab 💻🔬💊 @victorgreiff]

Absolutely thrilled to see our immune repertoire review out this week: fantastic collaboration with @mariottienca @vanessajmh @HabibBashour @KhangLeQuy @puneet021192!

[Mol Syst Biol @MolSystBiol]

Location matters! An epithelial cell’s position within a population determines its response to interferons through cell polarization & basolateral localization of the #interferon receptor ➡️ https://t.co/YgTtY1EInJ @BoulantLab @Megan_Stanifer @UFMedicine #cellheterogeneity

[Kevin Thurley @ThurleyLab]

Great to see the work of my first PhD student finally published in @ScienceAdvances, extending our data-based modeling framework to study a network of proliferating cell populations in chronic inflammation.
@DRFZ_Berlin @IEO_Bonn @ImmunoSens @HCM_Bonn
https://t.co/xhG45UjYrt