Tim Luongo

Early‑stage Biotech Advisor | Founder & Principal @ BridgeLine Translational Partners | Discovery, Nonclinical & Portfolio Strategy • Investor Readiness

[Tim Luongo @timluongo]

I am excited to share our most recent work from the
@baurlab published @nature revealing SLC25A51 expression regulates mitochondrial NAD+ levels and encodes the mammalian mitochondrial NAD+ transporter. #NAD #mitochondria #metabolism

https://t.co/WIoh4ClSmF

[Kivanc Birsoy @KivancBirsoy]

Our new study describing a "potential" mitochondrial glutathione transporter (SLC25A39 and 40). Congrats to all of my amazing lab members and collaborators involved in this work for the last 4 years. @RockefellerUniv @Nature @TriIMDPhD
https://t.co/3QkE6xoG9c

[Tim Luongo @timluongo]

@dhtomar @wakeforestmed @WFCardiology Congratulations! Welcome to NC!

[Dr. Melanie McReynolds @dr_ohsopretty]

What a journey! I can finally share with the world the work I’ve been able to accomplish during the time of my postdoctoral training.

🧵
https://t.co/B6Gbc7RBV1

[Tim Luongo @timluongo]

Therapeutic Discovery at StrideBio is hiring! Apply if you are interested in developing gene therapies for cardiovascular disease.

https://t.co/CjhNxCJtNL

[Circulation @CircAHA]

In the failing heart, short chain fatty acids (SCFA) are more readily oxidized than ketones & represent an unexplored source of energy production. Read more: https://t.co/AZ0VyHyi8P #AHAJournals @DougLewandowski

[Tim Luongo @timluongo]

@PaulTitchenell @AnnaGar33 @pennsurgery @PennIDOM @MolMetab Congratulations!!

[Paul Titchenell @PaulTitchenell]

Excited to share our recent work spearheaded by @AnnaGar33 that show an important role for hepatic FOXO transcription factors in driving stress-induced hyperglycemia and insulin resistance in mouse models of trauma @pennsurgery @PennIDOM @MolMetab
https://t.co/Au7oTpxOlO

[Tim Luongo @timluongo]

@dr_ohsopretty Sorry for your loss Melanie.

[Baur Lab @BaurLab]

Congrats to Sarmistha Murkherjee for her recent study revealing that SIRT3 is required for liver regeneration and that the benefits of boosting #NAD are independent of sirtuins.

https://t.co/9GTvTyfKJ0

[Gerta Hoxhaj Lab @Gerta_Hoxhaj]

We are excited to share the first paper from our lab @NatMetabolism. We discovered that mitochondrial NADP+ is essential to enable proline synthesis and reveal the first example of mammalian proline auxotrophy https://t.co/Prw7QAzT1t. 1/12

[Tim Luongo @timluongo]

@PaulTitchenell @APSPhysiology @PennMedicine @PennIDOM @PennCVI @UPennPhysiology @PennMedEVDCSO Congratulations!

[Jonas Thue Treebak @treebak]

Ablation of Nampt in AgRP neurons leads to neurodegeneration and impairs fasting‐ and ghrelin‐mediated food intake https://t.co/TjLwAULToY

[Jen Kwong @KwongLab]

Our new paper is out online! We uncovered a surprising ability of the adult heart to withstand defects to the mtDNA maintenance machinery. The developed vs. developing heart respond very differently to mito dysfunction. #mitochondria #heart

https://t.co/IzvjVMmCfU

[Tim Luongo @timluongo]

@wallyjoe33 Congratulations! This is really impressive!

[Tim Luongo @timluongo]

@McLellan_Lab Congratulations Jason! Well deserved!

[Tim Luongo @timluongo]

@BellaverBruna @erzimmer @dtleffa @jpfsouza33 @lucasudaros Happy birthday!! And congratulations!

[Rutter Lab @RutterLab]

We had a blast writing this mini-review on the recent discovery of the mito-NAD transporter in mammalian cells, & what it could mean for the broader field of NAD biology. @alexjbott @Yeyunouyang @giuliosf @KoryLab @timluongo @e_girardi @TrendsBiochem
https://t.co/FggfXnlUgC

[Vesna Todorović @Vesna_Tod]

D-day alert: Nature Cardiovascular Research site is now live! https://t.co/83lyGinUIB
To all my followers who have cardiovascular and blood biology @❤️ and 'in their veins', please follow us @NatureCVR We're open for submissions in mid-April!

[Tim Luongo @timluongo]

@dr_ohsopretty Congratulations Melanie!!

[Tim Luongo @timluongo]

@LACambronne @CambronneLab Happy Birthday Lulu!