Charlotte Capitanchik 🌙

Likes biology, programming & short walks to buy maltesers. Postdoc @ UK DRI Kings College London with @ule_lab.

[Charlotte Capitanchik 🌙 @tiny_captain]

Take two of srsly moving to Bluesky #sciencetwitter we gotta skeedaddle 🏃🏻‍♀️

[Simon Duerr @simonduerr]

This is great! @NIAIDNews have launched a collection of public domain illustrations (currently 550 individual icons) https://t.co/qYzIsbr0TH

[Charlotte Capitanchik 🌙 @tiny_captain]

@BonifacinoJuan @iamscicomm You can also try the parallel project https://t.co/4UTZHo1NUd

[nature @Nature]

Much of the success of breakthroughs, such as AlphaFold, is thanks to a database of protein structures dreamed up in the 1960s by Helen Berman https://t.co/j7l4MJ5OeU

[Rainer Melzer @UCDflowerpower]

GWAS for Nobel prize laureates.

[Nature Reviews Genetics @NatureRevGenet]

To launch this collection the following #Review is free to download for 1 month:
From computational models of the splicing code to regulatory mechanisms and therapeutic implications https://t.co/94P3YXVUid by @tiny_captain, @OscarWilkins16, @nils_f_wagner, @gagneurlab & @ule_lab

[Oscar Wilkins @OscarWilkins16]

Our paper on cryptic splicing-controlled protein expression, which we hope will inspire safer and more adventurous gene therapy approaches for ALS and FTD, has been published in @ScienceMagazine https://t.co/YriG3I4ILF

[Max Z. Y. J. Chien @MaxZYJChien]

We are finally here. Thanks to @OscarWilkins16 and @FrattaLab gave me this wonderful chance to participate in this fantastic research.

Creation of de novo cryptic splicing for ALS and FTD precision medicine | Science https://t.co/8fI2NKngcu

[Charlotte Capitanchik 🌙 @tiny_captain]

Hot on the heels of the review comes @OscarWilkins16 beautiful work in @ScienceMagazine describing a new therapeutic approach for ALS designed using SpliceAI to implement directed in silico evolution https://t.co/5vtgsnfE1L

[gagneurlab @gagneurlab]

Honoured to have written this review with Jernej Ule’s lab on the splicing code, spanning modeling, mechanisms and its implication for therapeutics designs. Wonderful teamwork.

[Charlotte Capitanchik 🌙 @tiny_captain]

@AArgoetti thank you!!

[Charlotte Capitanchik 🌙 @tiny_captain]

in this article we delve into the world of splicing models! i specifically focused on the latest omics technologies that will help us to interpret and train models, looking towards future opportunities. lots of biorxiv citations because the field is moving so fast!!!

[Nature Reviews Genetics @NatureRevGenet]

From computational models of the splicing code to regulatory mechanisms and therapeutic implications https://t.co/94P3YXVmsF #Review by @tiny_captain, @OscarWilkins16, @nils_f_wagner, Julien @gagneurlab & Jernej @ule_lab
@HelmholtzMunich @TU_Muenchen @TheCrick @KingsCollegeLon

[Charlotte Capitanchik 🌙 @tiny_captain]

was very fun to work with @nils_f_wagner and @gagneurlab on this and also a great opportunity to highlight @OscarWilkins16's awesome work designing therapeutics using splicing models

[Rory Maizels @rorymaizels]

🚨The Briscoe lab are hiring! Apply by Oct 9 to:

• build custom single-cell technologies to study dev bio
• collaborate on projects spanning cancer therapy, immune profiling and neurodegenerative disease
• learn valuable skills for academia or industry
https://t.co/e6AWFJqjiB

[londonomics @Londonomics_net]

School’s back and so are we with another co-working session and social!

This time we’ll be at the @SGDPCentreKCL, with the social being opened up to all ECR’s within the centre 😎

As always, free 🍕 and 🍻🥤

https://t.co/GqtND4xrjB

[Charlotte Capitanchik 🌙 @tiny_captain]

@firewomon @CityCorpHeath And how exactly are we supposed to prove we were “born female in sex”?

[Miha Modic @paraspeckle]

How can cellular signalling swiftly & selectively remodel the transcriptome to drive biological transition? How this switch is orchestrated has been a mystery... 🧵

https://t.co/3z4dcVoztD

[Sarah Marzi @sj_marzi]

I'm excited for whoever will employ @kittybmurphy - she's an incredible computational geneticist and will be the most amazing addition to any team she joins. Super proud to see this superstar student move on and develop her academic career 🥰

[Charlotte Capitanchik 🌙 @tiny_captain]

come find some summer motivation with us! or at least free pizza :D

[londonomics @Londonomics_net]

Our next co-working session is next Thursday 1st Aug at QMUL campus! Sign up to join https://t.co/8ikxciYtwR

[𝕐 @nomad421]

Today is the day, it's been over a year in the making. #Bioconda now supports OSX-arm64 runners and builders! #bioconda for Apple silicon is here!