Thrilled to share this: hand to hand with the amazing @F_Mikus and @HiralABShah , with incredible guidance from @CentrioleLab , @Dey_Gautam , and @dudin_o , we’ve unlocked the cytoskeletal secrets of 200 protists! 🦠 #protists#PlanExM#UExM 👇https://t.co/SjXKknJJwj
Its out !!! 🥳
Very proud to announce that my PhD work is now published in Nature communication: https://t.co/UsC9lgAwXC
We developed #iUExM, an optimized iterative expansion protocol allowing 16 to 26 fold homogeneous expansion together with specific bright labelling !
Excited to announce the publication of our latest paper "CCDC15 localizes to the centriole inner scaffold and controls centriole length and integrity" in @JCellBiol! Congratulations to all contributing authors from my lab and our collaborators @CentrioleLab.
Our protocol for #Chlamy#UExM, first published looking at IFT assembly with @bengeliscious, is out. We highlight fixation options to look at different compartments, such as the chloroplast. Special props to @umutbatmann for his stunning images, including the cover!
@CytoLabKoc@dudin_o@samuelddean@AydoganLab @CentrioleLab As I recall, the homemade mNG antibody did not work in expansion either. As far as I know we don’t have any working mNG antibody for expansion
Here is the our latest on CCDC66 protein and it's function on ciliogenesis and cilium length regulation. I will mention the key findings from the paper. 👇
Centrosome tweeps, "Centrosomes in Development, Disease and Evolution" hybrid meeting will be in Istanbul on 26-29 September, 2023. We secured funding from @EMBO@Co_Biologists, registration will start soon. Join us for the largest international #centrosome meeting. Please RT!
Thrilled to present my PhD work about the development of #iUExM 🥳
Here, we introduce an optimized versatile protocol using iterative expansion to reach #SMLM resolution on conventional widefield or confocal fluorescence microscopes on cells & tissues.
https://t.co/jB4f59QWni
Our study with @CentrioleLab @GaiaPigino on the Chlamydomonas ciliary base is online @ScienceMagazine: https://t.co/sWH2YFsMER
We combined #CryoET🔬 with #UExM🔬 to:
1⃣ Reveal the structure of the transition zone (movie👇)
2⃣ Observe the assembly of IFT trains (next tweet)
1/🧵
New paper alert!! Our work on dissection of the non-ciliary CCDC66 functions is now published in @PLOSBiology. This is our second paper in PLOS Biology and second time around, we had a great editorial experience. We also thank the reviewers for their constructive comments.
The ciliopathy protein CCDC66 controls mitotic progression and cytokinesis by promoting microtubule nucleation and organization https://t.co/RdoDaJ3ODJ
The ciliopathy-linked protein CCDC66 is only known for its ciliary functions. A new study in #PLOSBiology reveals that CCDC66 also has extensive non-ciliary functions in regulating #mitosis and #cytokinesis@CytoLabKoc https://t.co/xdCMPAVKqT
It feels amazing to finally share that my first first-author paper is now online as a preprint! 🥳 https://t.co/jtTaUjofjP This work is done when I was a master student in @CytoLabKoc in collaboration with Jovana Deretic. Read below our main findings 👇
📄 ENKD1 is a centrosomal and ciliary microtubule-associated protein important for primary cilium content regulation
✏️ By Fatmanur Tiryaki, Jovana Deretic and Elif Nur Firat-Karalar @CytoLabKoc@kocuniversity
🔗 https://t.co/HMF5pTXAgM
#centrosome#ENKD1#Hedgehogsignaling
Finally out! So happy to share with you this paper highlighting the presence and role of a structural zipper maintaining photoreceptor cell integrity! https://t.co/8KDtYRgUWm
Paper accepted!! It was already published in @biorxivpreprint but still, receiving the acceptance email is special. Big congratulations to my previous master student @umutbatmann and postdoc Jovana Deretic.