ISCRM at UW

The Institute for Stem Cell and Regenerative Medicine at the University of Washington is changing the way human beings confront chronic disease.

[ISCRM at UW @UWISCRM]

The sixth annual Cascadia Corridor Regenerative Medicine Research Symposium is underway in Seattle with a keynote from @DrSakiyama! We’re thrilled to welcome friends and colleagues from @BCRegMed @UBC @uoregon and OHSU. #stemcells #regenerativemedicine

[Cole DeForest @coledeforest]

Our latest collaborative paper with David Baker's lab is now live in Cell Biomaterials (@CellBiomat, Cell Press)! Check out "Stimuli-triggered Formation of De Novo-designed Protein Biomaterials"!

🔓 : https://t.co/GSSJPePbgX

[ISCRM at UW @UWISCRM]

An ISCRM research team of biologists, engineers, and physicians shows that fibroblasts, often thought of as helpers, may weaken the heart by causing a harmful cycle of stiffening and scarring, and pinpoints a potential fix.

[UW Medicine Newsroom @uwmnewsroom]

Fibroblasts, cells that help repair heart damage, can also cause harm in conditions like dilated cardiomyopathy. Shutting down a fibroblast signaling pathway restores heart functioning in lab model @ScienceMagazine @UWBioE @UWISCRM https://t.co/Q8wXVNcSMf

[ISCRM at UW @UWISCRM]

A new study in @ScienceAdvances from @coledeforest introduces PhoCoil, a recombinant protein hydrogel with light-triggered disassembly, enabling precise spatiotemporal control of cell delivery, advancing tools for regenerative medicine + cell therapy.
https://t.co/WmUzWAiBlS

[Nature Chemical Biology @nchembio]

A new paper by @justindaholee, @uwberndtlab, @UWMolES, @UWBioE, @UWISCRM, @NAPECenter highlights far-red chemigenetic H2O2 reporter oROS-HT635, which enables detailed insights into the intricate intracellular and intercellular H2O2 dynamics

https://t.co/uLwPn2fCi4

[Beno Freedman @benofreedman]

We got the cover!!

[F Moussavi-Harami, MD @FMoussaviHarami]

Our paper in @BiophysJ on cardiac muscle parameter estimations! Work led by Travis Tune from @UW_CTMR in collaboration with @JD98119 and Tom Daniel! @UWBioE @UWISCRM @uwlabmedpath
Bayesian estimation of muscle mechanisms and therapeutic targets using... https://t.co/wXJV6Xq03L

[The Nobel Prize @NobelPrize]

”David Baker, Demis Hassabis and John Jumper, your ground-breaking work in computational protein design and protein structure prediction has revolutionised these fields. It has opened up completely new possibilities to design proteins that have never been seen before, and we now have access to predicted structures of all 200 million known proteins. These are truly great achievements.”

Watch the very moment the chemistry laureates received their Nobel Prize diplomas and medals during the 2024 Nobel Prize award ceremony.

#NobelPrize

[ISCRM at UW @UWISCRM]

Congratulations @kellystevenslab!

[UW Bioengineering @UWBioE]

Congratulations to #UWBioE professor Kelly Stevens on receiving the 2024 @BMESociety Mid-Career Award! Her pioneering work in synthetic biology, 3D bioprinting & organ engineering is shaping the future of biomedical tech.
Learn More: https://t.co/VbaNB562d8

[Kelly Stevens @kellystevenslab]

Calling all faculty candidates (postdocs, Asst Profs, senior grad students) - Apply to @UWBioE! Job ad at link below. If you are considering applying and have questions on the ad, please email or DM me. Come join us, UW is amazing! https://t.co/SaWp9k7nsD

[ISCRM at UW @UWISCRM]

Researchers at @UWISCRM and @ucsdbe use a multiscale modeling tool show how small infusions of myosin can have a big impact on the whole heart. @UW_CTMR @LabRegnier @UWBioE
https://t.co/gOYp1FsOAE

[ISCRM at UW @UWISCRM]

The Sniadecki Lab and the @UWDentalSchool have used a 3D modeling system, originally developed to measure the force of beating heart cells, to reveal insights about the cellular dynamics at work in the periodontal ligament. https://t.co/EsKzEcxlbJ

[ISCRM at UW @UWISCRM]

Postdocs nationwide:

Applications are now being accepted for the 2025 Inclusive Leadership Workshop (May 5-8 in Seattle).

No program costs. Hotel and lodging covered.
Space is limited!

#inclusiveleadership #diversityinSTEM

https://t.co/HAA1E5ch2o

[Gordana Vunjak-Novakovic @GVNlab]

Join us this Wednesday, Sept. 25th at 3pm EST for a #TissueTalk with @UW Prof. @coledeforest on “User-programmable hydrogel biomaterials to probe and direct 4D stem cell fate.”

See you there: https://t.co/cvdpWVcfPJ

[Cole DeForest @coledeforest]

Want to photorelease proteins from biomaterials w/o exogenous light? Use BRET!

"Bioluminescence Resonance Energy Transfer (BRET)-Mediated Protein Release from Self-Illuminating Photoresponsive Biomaterials" is live @J_A_C_S!

📜:https://t.co/ScUe0Vkn3E

Congrats @teresarappphd!

[Cole DeForest @coledeforest]

We're just ONE WEEK AWAY from the Society for Biomaterials (@SFBiomaterials)'s inaugural Northwest Symposia here in Seattle @UW on Sept. 19-20, 2024!

Exciting speakers, posters, panel, social, & networking!

Registration is still open! https://t.co/aXQasDosWT

Come join the fun!

[ISCRM at UW @UWISCRM]

Congratulations @BrizziaMunoz!

[Cole DeForest @coledeforest]

Belated congrats to DOCTOR @BrizziaMunoz on successfully defending her @UWBioE thesis work on controlling 4D cell fate using photoactivatable proteins! What an exciting set of stories that she has been involved with! Now on to bigger and better things! 🎉

[Jeff Rasmussen @jraslab]

Many thanks to the LEO Foundation (@LEOFondet) for supporting our work on the cell biology of skin immune cells!

[Nobu Hamazaki @Nobu_Hamazaki]

Excited to share our human RA-gastruloid model in @NatureCellBio! Early retinoic acid supplementation, followed by later Matrigel addition, robustly induces human embryonic morphologies and diverse cell lineages, including somitic, renal, cardiac, and neural cell types in #gastruloid. https://t.co/buaAcqxGlZ

[Cory Simpson, MD, PhD, FAAD (he/him) @CorySimpsonMD]

Grateful for an @american_skin1 grant to support our work @SimpsonLabUW @DermatologyUW to understand how #keratinocytes mature via #autophagy to form the outer skin layers and how this is disrupted in thick, scaly #psoriasis plaques (image from DermNetNZ). https://t.co/2oLD1kL9yl