#Guanidine was known since the 1870s to affect muscle function. Vertebrates have guanidine-sensing #riboswitch RNAs linked to genes relevant to muscle disorders, including some for Ca2+ signaling and others relevant to #ataxia symptoms. @NatureComms https://t.co/TdoTLvIL0t
Thrilled to share the next chapter in my career — I’ve been named the inaugural Chair of the Department of Dermatology at Mass General Brigham (MGB).
It’s an incredible honor to lead such an accomplished, innovative team—arguably the most forward-thinking in our field.
Had a great scientific time at RNA Tokyo @ IQB UTokyo with Prof. Phillip Zamore and RNA PIs from the Tokyo area. Big thanks to Prof. Yuki Tomari for organizing! Great discussions—and a fun evening at Hantei after the seminar.
Students and postdocs - apply for a Travel Grant to attend the 2025 Annual Meeting!
Travel Grants are between $1,000-$1,500 USD and funding may be available to assist with registration fees.
Apply by July 15!
Learn more at: https://t.co/PTpwEn94xx
#ots25#ots
”Paul's dying wish was simple but profound: Find a cure for the incurables," said Swanee DiMare.
@UMassChan's research building is now named for her husband, Paul J. DiMare.
”It stands as a tribute to the life he lived and a beacon of hope for the lives we still aim to save."
Stanford paid 35,000 people to quit social media.
This was the largest study on emotional health in history.
The results were so shocking, scientists called it "comparable to therapy."
Here's what happens when you break free from the algorithm:
🧵
I stand with dozens of other biopharma leaders highlighting the potential catastrophic effects of proposed research cuts on bringing innovation to patients! https://t.co/ZlDal4Euug
📣Today we announced that we intend to acquire @23andMe with plans to maintain their consumer genetics business and advance our shared goal of improving human health and wellness. https://t.co/cujfaF5rF📣Today we announced that we intend to acquire @23andMe with plans to maintain their consumer genetics business and advance our shared goal of improving human health and wellness. https://t.co/cujfaF5rF📣Today we announced that we intend to acquire @23andMe with plans to maintain their consumer genetics business and advance our shared goal of improving human health and wellness. https://t.co/cujfaF5rF2
Amazing story that highlights the transformative medicines that our research institutions and biotech companies can bring to patients and societies!
We must preserve these advances for our future! https://t.co/ojweKYlEb9
For readers interested in GLP-1-based therapies for obesity, diabetes, metabolic liver disease, hypertension, neurodegenerative disorders and more, here's a comprehensive review https://t.co/X714Dj2BNb
https://t.co/i1Tpxj7DWP
Our newest paper on enzymatic synthesis of hypermodified DNA bearing functional groups mimicking amino acid side chains in enzyme active sites just published in @ChemEurJ . https://t.co/CnQ3FCcmXf @IOCBPrague@VSCHT@science_charles@Akademie_ved_CR
Today "a milestone in the evolution of personalized therapies for rare & ultra-rare inborn errors of metabolism"
—the 1st human to undergo custom genome editing
—outgrowth of decades of NIH funded research
https://t.co/HmJxYWDCV7
https://t.co/4DsNELnBut @NEJM
https://t.co/y7NMGPpXnE
Today in @ScienceMagazine we report the development of a laboratory-evolved CRISPR-associated transposase (evoCAST) that supports therapeutically relevant levels of RNA-programmable gene insertion in human cells, a collaboration with @SternbergLab.
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https://t.co/ZLHtZm5Gmw
📢 @RNACanadaC2R2 and @Moderna’s The Discovery of the Year Award is open for nominations!
This award recognizes groundbreaking RNA research by Canadian researchers. Nominate yourself or someone else today!
🗓️ Deadline: May 30, 2025
🏆 Prize: $7,000
🔗 https://t.co/5unkxNZXFK
Else Kröner Fresenius Prize for Medical Research 2025: Anastasia Khvorova, professor of RNA therapeutics @UMassChan, is being honored with 2.5 million € for her pioneering work in the field of RNA-based therapies. Here is a preview of the award film. #EKFprize25#RNA#Huntington
Our #RNA multimer paper out now in @nature! #cryoEM of 2 distinct nanocages GOLLD and ROOL and membrane-associated OLE. Multimers at ultra-low concentrations, special covariance for cross-molecule kissing loops, and speculation on function https://t.co/ZihCKHIIcX. 1/2